男女媾精，万物化生，胎虽孕于精血，实赖先天一气结成，所谓二五之精妙合而凝也。惟精凝其血，是精
胜为男。血聚其精，是血胜为女。骈胎品胎乃精气之分岐四射而血凝之，亦非一路焉。男有不可为父者，得阳气
之亏。女有不可为母者，得阴气之塞。故种子之法，男以补肾填精为要，女以养血调经为先，使精血充足，经候
无愆，则男无不父，女无不母矣。
督脉生病，女子不孕，少阴脉微弱涩，年少得之为无子，中年得之为绝产，肥人脉细胞有寒饮，故令少子，
瘦人脉涩，冲无余血故不能孕。
男贵养精，女宜调血，经前腹痛须调气兼以活血，经后腹痛宜补血或兼益气。阴虚者，滋阴壮水以调元气，
阳虚者，补肾扶阳以生精血。
主以四物汤加砂仁、香附、杜仲、续断，血瘀加桃仁、原红花，血虚加阿胶、黄明胶，血热加山栀、丹皮，
寒加炮姜、肉桂，
气滞加木香、香附，气虚加人参、黄 ，虚寒秦艽、桂，虚热先期汤，各随脉证调治，庶克有子。
加味种子四物汤
治冲任两虚不孕，脉虚涩者。
熟地（五钱） 当归（三钱） 白术（一钱半，炒） 川芎（一钱） 白芍（一钱半，炒） 茯苓（一钱半）
阿胶（三钱，麦炒） 香附（二钱，酒炒） 续断（三钱，酒炒） 炙草（五分）
水煎去渣，冲炒黄砂仁末五分温服。
冲任两虚不能交媾水火，是胞中血少气涩，故无以孕精而娠焉。熟地补阴滋血，当归养血荣经，川芎活冲脉之
血，白芍敛任脉之阴，白术健脾生血，阿胶补血益阴，香附调气解郁，炙草缓中益胃，茯苓渗湿以清于室，续断续
筋以雄经脉也。水煎温服，稍佐砂仁，调胃醒脾，使脾胃调和则血室充足而气无滞涩之患，何有冲任不调，媾精
不孕哉。
调经种玉汤
治血虚挟滞不孕，脉涩弦者。
熟地（五钱） 吴茱（一钱，醋炮炒） 白芍（一钱半，酒炒） 川芎（一钱） 当归（三钱） 香附（二钱，
酒炒） 茯苓（一钱半） 丹皮（一钱半） 陈皮（一钱半） 延胡（一钱半，酒炒）
水煎去渣温服。
血亏挟滞冷热不调，致天癸愆期，故不能成孕焉。熟地补阴滋血，当归养血荣经，川芎活冲脉之血以调经，
白芍敛任脉之阴以和络，延胡活血滞，香附调气滞，吴茱温肝逐冷，陈皮利气和胃，丹皮凉血退热，茯苓渗湿和
中也。水煎温服，使血活滞行，则寒消热化而天癸如其常度，无不媾精而成孕矣。如过期色淡加炮姜、肉桂以温
经暖血，血先期色鲜加条芩、栀子以清热凉血，此随症加减之法，无不丝丝入扣。
增损三才丸
治血少无孕，脉软涩者。
天冬（三两，去心炒） 熟地（五两） 人参（一两半，蒸） 远志（一两半，焙） 茯苓（一两半，蒸）
鹿角（一两半，酥炙） 北味（一两，焙）
为末炼蜜丸，温酒下三钱，年老加混元衣酒洗炙末。一方加白马茎，酒洗炙末。一方加熟附子，盐水炒黑。
一方加麦冬酒浸蒸。一方加续断酒炒。一方加沉香磅因末蒸。
血少经枯，不能滋荣百脉，故子宫干涩无以媾精而孕子焉。天冬清心润肺兼能益阴壮水，熟地滋补阴血，
更能荣养经脉，人参扶元补气，远志通肾交心，茯苓渗湿以清子室，北味收敛以滋津液，鹿角壮督脉以暖胞门也。
蜜丸酒下，使血荣经润，则子宫无枯涩之患而天癸如其常度，无不媾精而孕育矣。年老加混元衣大补血气，白马茎
之扶阳，熟附子之补火，麦门冬之润燥，川续断之接续经脉，沉香末之温融下焦，因形定诊，无不头头是道。
青蒿乌鸡丸
治潮热食少，经愆无子，脉软弦数者。
青蒿（一斤） 人参（四两） 黄 （四两，蜜炙） 当归（四两） 香附（一斤，制） 茯苓（二两）
川芎（二两） 白术（四两，制） 丹皮（二两） 白芍（二两，炒） 鳖甲（六两，醋制） 地骨皮（三两）
艾叶（二两，醋炒）
制为末，取白丝毛乌骨雄鸡一只，去肠垢留腹入熟地八两，好酒煮烂去骨，同前药焙脆为末，仍用煮鸡酒糊
熟糯粉，干湿可丸余酒收入，仍用温酒下三五钱。
气虚不能鼓运其血，致热遏经中而潮热食少，天癸愆期，故不能生子焉。人参扶元补气，黄 实卫补中，白
术健脾土以鼓运乎血，当归养血脉以营运乎经，川芎行血中之气，白芍敛经脉之阴，香附调气解郁，鳖甲散结滋
阴，牡丹皮凉血以平相火，地骨皮清肌以退潮热，茯苓渗湿兼清子室，艾叶理血 暖子宫，青蒿解郁热而直清肝
胆也。熟地煮鸡得水木同气，引领诸药扶阴益血鼓运营气，即以煮鸡酒丸，仍用好酒送下，使气壮血行，则冲任
融和而营卫调适，其潮热无不退，饮食无不增，何患天癸不调，不
能生子耶。
紫河车丸
治虚寒不孕，脉软弱者。
紫河车（一具，白酒洗，银针挑净紫筋） 大熟地（八两） 当归身（四两） 白芍药（二两，酒炒）
冬白术（四两，制） 淮山药（四两，炒） 金香附（二两，酒炒） 拣人参（四两） 紫石英（二两，醋炒）
甘枸杞（四两） 蕲艾叶（二两，醋炒） 小川芎（二两）
各药同河车入陈酒煮烂，收干晒脆为细末，蜜丸温酒下三五钱。
气血两亏子宫不暖，致天癸愆期无以孕育而生子焉。熟地补阴滋血，人参补气扶元，当归养血荣经，白术健
脾生血，川芎行血海以调经，白芍敛阴血以和络，香附调气解郁，山药补脾益阴，蕲艾叶理血气以温血室，紫石
英涩血气以暖子宫，甘枸杞滋培肾脏，紫河车大补血气，入酒煮烂，收焙炼蜜以丸之，温酒以下之，俾血气内旺
则子宫温暖而冲任融和，天癸无不调，自能孕育而生子矣。
调生丸
治年久不孕，脉数紧涩者。
熟地（五两） 当归（三两） 白芍（两半，酒炒） 川芎（一两） 泽兰（二两） 白术（两半，炒）
石斛（二两） 干姜（一两，炒） 丹皮（一两，酒炒） 肉桂（一两，去皮） 延胡（二两，酒炒）
制为末，淡醋丸，温酒下三钱。
血亏挟滞冷热不调，致经愆腹痛不能孕生焉。熟地补阴滋血，当归养血荣经，川芎行血海以调经，白芍敛阴
血以和脉，丹皮凉血热，白术健脾丸元，石斛补虚退热，干姜温胃散寒，泽兰通利经脉，肉桂温暖营血，延胡索化
血滞以调和经脉也，醋丸以收之，酒下以行之，使冷热并化则经气调和而腹痛无不退，天癸无不调，何有不能生
子之患哉。
When male and female engage in intercourse, their essence and spirit combine, giving rise to all things. Although the fetus is conceived from essence and blood, it actually relies on the condensation of the primordial Qi of the congenital constitution, as described by the phrase "the exquisite combination of the two fives (Yin and Yang) condenses." If essence condenses with blood, essence prevails, resulting in a male. If blood gathers around essence, blood prevails, resulting in a female. Twins or multiple births occur due to the divergence and scattering of essence and qi accompanied by blood coagulation, not through a single pathway. Men who cannot become fathers suffer from a deficiency of Yang Qi. Women who cannot become mothers suffer from obstruction of Yin Qi. Therefore, the method for promoting conception involves men focusing on tonifying the Kidney and filling essence, while women prioritize nourishing blood and regulating menstruation. When essence and blood are sufficient and the menstrual cycle is regular without deviation, men will invariably become fathers, and women will invariably become mothers.
Diseases of the Du Mai (Governing Vessel) can cause infertility in women. A weak and choppy pulse at the Shaoyin position indicates no offspring in young women, and sterility in middle-aged women. In obese women, a fine pulse with cold-fluid retention leads to reduced fertility. In thin women, a choppy pulse indicates insufficient residual blood in the Chong Mai (Penetrating Vessel), preventing conception.
Men should value the preservation of essence, while women should focus on regulating blood. Abdominal pain before menstruation requires regulating Qi along with invigorating blood; abdominal pain after menstruation benefits from nourishing blood or supplementing Qi. For Yin deficiency, nourish Yin and strengthen Water to regulate Yuan Qi. For Yang deficiency, tonify the Kidney and support Yang to generate essence and blood.
The primary treatment uses Si Wu Tang (Four Substances Decoction) added with Amomum fruit (Sharen), Cyperus rhizome (Xiangfu), Eucommia bark (Duzhong), and Dipsacus root (Xuduan). Add Peach kernel (Taoren) and Safflower (Honghua) for blood stasis; add Donkey-hide gelatin (Ejiao) and Yellow Ming Gelatin (Huangming Jiao) for blood deficiency; add Gardenia fruit (Shanzhi) and Moutan bark (Danpi) for blood heat; add Processed Ginger (Paojiang) and Cinnamon twig (Rougui) for cold; add Aucklandia root (Muxiang) and Cyperus rhizome (Xiangfu) for Qi stagnation; add Ginseng (Renshen) and Astragalus root (Huangqi) for Qi deficiency. For deficiency-cold, use Kochia herb (Qinjiao) and Cassia twig (Guizhi); for deficiency-heat, use Xianqi Tang (Premature Period Decoction). Treatment should be adjusted according to the pulse and symptoms to facilitate conception.
Modified Seed-Generating Si Wu Decoction
Indicated for infertility due to deficiency of both Chong and Ren vessels, with a deficient and choppy pulse.
Prepared Rehmannia root (Shudi, 5 qian)
Angelica sinensis root (Danggui, 3 qian)
Atractylodes macrocephala rhizome (Baizhu, 1.5 qian, stir-fried)
Ligusticum chuanxiong rhizome (Chuanxiong, 1 qian)
White Peony root (Baishao, 1.5 qian, stir-fried)
Poria cocos sclerotium (Fuling, 1.5 qian)
Donkey-hide gelatin (Ejiao, 3 qian, stir-fried with wheat bran)
Cyperus rotundus rhizome (Xiangfu, 2 qian, stir-fried with wine)
Dipsacus asperoides root (Xuduan, 3 qian, stir-fried with wine)
Prepared Licorice root (Zhigancao, 0.5 qian)
Decoct in water, remove dregs, mix with 0.5 qian of finely ground stir-fried Amomum fruit powder, and take warm.
Deficiency of Chong and Ren vessels prevents the interaction of Water and Fire. The uterus has insufficient blood and stagnant Qi, thus unable to conceive. Prepared Rehmannia nourishes Yin and generates blood; Angelica nourishes blood and enriches meridians; Ligusticum activates blood in the Chong Mai; White Peony astringes Yin of the Ren Mai; Atractylodes strengthens the Spleen to generate blood; Donkey-hide gelatin tonifies blood and benefits Yin; Cyperus regulates Qi and relieves depression; Prepped Licorice moderates the Middle and benefits the Stomach; Poria leaches out dampness to clear the uterus; Dipsacus strengthens tendons and bones to fortify meridians. Decoct in water and take warm. Adding a small amount of Amomum regulates the Stomach and awakens the Spleen. When the Spleen and Stomach are harmonious, the Blood Chamber is sufficient, and Qi flows without stagnation. How could there be disharmony of Chong and Ren leading to infertility?
Regulating Menstruation and Jade-Seed Decoction
Indicated for infertility due to blood deficiency with stagnation, presenting with a choppy and wiry pulse.
Prepared Rehmannia root (Shudi, 5 qian)
Evodia fruit (Wuzhuyu, 1 qian, processed with vinegar and stir-fried)
White Peony root (Baishao, 1.5 qian, stir-fried with wine)
Ligusticum chuanxiong rhizome (Chuanxiong, 1 qian)
Angelica sinensis root (Danggui, 3 qian)
Cyperus rotundus rhizome (Xiangfu, 2 qian, stir-fried with wine)
Poria cocos sclerotium (Fuling, 1.5 qian)
Moutan bark (Danpi, 1.5 qian)
Tangerine peel (Chenpi, 1.5 qian)
Cyathula officinalis root (Yanhusuo, 1.5 qian, stir-fried with wine)
Decoct in water, remove dregs, and take warm.
Blood deficiency with stagnation causes imbalance of cold and heat, leading to irregular Tian Gui (menstruation), thus preventing conception. Prepared Rehmannia nourishes Yin and generates blood; Angelica nourishes blood and enriches meridians; Ligusticum activates blood in the Chong Mai to regulate menstruation; White Peony astringes Yin of the Ren Mai to harmonize collaterals; Cyathula invigorates blood and removes stagnation; Cyperus regulates Qi and resolves stagnation; Evodia warms the Liver and dispels cold; Tangerine peel promotes Qi movement and harmonizes the Stomach; Moutan clears blood heat; Poria leaches dampness and harmonizes the Middle. Decoct in water and take warm. This ensures blood circulation and stagnation resolution, eliminating cold and transforming heat, restoring normal Tian Gui rhythm, and facilitating conception. If menstruation is delayed with pale color, add Processed Ginger and Cinnamon Twig to warm meridians and blood. If menstruation occurs early with bright red color, add Scutellaria baicalensis root (Huangqin) and Gardenia fruit to clear heat and cool blood. These modifications fit the symptoms precisely.
Modified Sancai Pill
Indicated for infertility due to low blood volume, with a soft and choppy pulse.
Asparagus tuber (Tiandong, 3 liang, heart removed and stir-fried)
Prepared Rehmannia root (Shudi, 5 liang)
Ginseng root (Renshen, 1.5 liang, steamed)
Polygala root (Yuanzhi, 1.5 liang, baked)
Poria cocos sclerotium (Fuling, 1.5 liang, steamed)
Deer antler (Lujiao, 1.5 liang, roasted with butter)
Schisandra berry (Beiwuweizi, 1 liang, baked)
Grind into powder, make pills with refined honey, and take 3 qian with warm wine. For elderly patients, add Huiyuan Yi (ash from clothing worn by a wet nurse), washed in wine, roasted, and powdered. Alternatively, add Horse penis (Baima Jing), washed in wine, roasted, and powdered. Alternatively, add Prepared Aconite root (Shufu Zi), stir-fried black with salt water. Alternatively, add Ophiopogon tuber (Maidong), soaked in wine and steamed. Alternatively, add Dipsacus root (Xuduan), stir-fried with wine. Alternatively, add Agarwood powder (Chenxiang), steamed.
Low blood and amenorrhea fail to nourish the hundred vessels, causing uterine dryness and inability to conceive. Asparagus clears the Heart and moistens the Lungs while benefiting Yin and strengthening Water; Prepared Rehmannia tonifies Yin and blood, nourishing meridians; Ginseng supports Yuan Qi and supplements Qi; Polygala connects the Kidney and Heart; Poria leaches dampness to clear the uterus; Schisandra astringes to generate fluids; Deer antler strengthens the Du Mai and warms the uterus. Pills taken with wine nourish blood and moisten meridians, preventing uterine dryness and restoring normal Tian Gui, facilitating conception. For the elderly, Huiyuan Yi greatly tonifies Qi and blood; Horse penis supports Yang; Prepared Aconite tonifies Fire; Ophiopogon moistens dryness; Dipsacus reconnects meridians; Agarwood warms the Lower Jiao. Diagnosis based on condition yields precise results.
Qinghao Black-Bone Chicken Pill
Indicated for tidal fever, poor appetite, irregular menstruation, and infertility, with a soft, wiry, and rapid pulse.
Artemisia annua herb (Qinghao, 1 jin)
Ginseng root (Renshen, 4 liang)
Astragalus root (Huangqi, 4 liang, honey-roasted)
Angelica sinensis root (Danggui, 4 liang)
Cyperus rotundus rhizome (Xiangfu, 1 jin, processed)
Poria cocos sclerotium (Fuling, 2 liang)
Ligusticum chuanxiong rhizome (Chuanxiong, 2 liang)
Atractylodes macrocephala rhizome (Baizhu, 4 liang, processed)
Moutan bark (Danpi, 2 liang)
White Peony root (Baishao, 2 liang, stir-fried)
Softshell turtle shell (Biejia, 6 liang, vinegar-processed)
Groundcherry root (Digupi, 3 liang)
Mugwort leaf (Aiye, 2 liang, vinegar-stir-fried)
Grind into powder. Take one white silk-feathered black-bone rooster, clean intestines, leave abdomen intact, insert 8 liang of Prepared Rehmannia, and boil well in good wine until tender. Remove bones, dry and roast with the powder. Use the chicken broth to bind glutinous rice flour into pills of appropriate consistency. Store remaining wine with the pills. Take 3-5 qian with warm wine.
Qi deficiency fails to propel blood, causing heat trapped in the menses, leading to tidal fever, poor appetite, and irregular Tian Gui, preventing conception. Ginseng supports Yuan Qi and supplements Qi; Astragalus secures the Exterior and tonifies the Middle; Atractylodes strengthens Spleen Earth to propel blood; Angelica nourishes blood vessels to circulate in meridians; Ligusticum moves Qi within blood; White Peony astringes Yin of meridians; Cyperus regulates Qi and relieves depression; Softshell turtle shell dissipates nodules and nourishes Yin; Moutan cools blood to calm Minister Fire; Groundcherry clears muscle layer to reduce tidal fever; Poria leaches dampness and clears the uterus; Mugwort regulates blood and warms the uterus; Artemisia resolves depressed heat and directly clears Liver and Gallbladder. Prepared Rehmannia boiled with chicken shares the same Qi as Water and Wood, guiding herbs to nourish Yin, benefit blood, and promote Qi circulation. Pills made with chicken broth and taken with wine strengthen Qi and move blood, harmonizing Chong and Ren, adjusting Ying and Wei. Tidal fever subsides, appetite increases, and Tian Gui regulates, enabling conception.
Ziheche Pill
Indicated for infertility due to deficiency-cold, with a weak and soft pulse.
Placenta human (Ziheche, 1 unit, washed in white wine, purple veins removed with silver needle)
Large Prepared Rehmannia root (Shudi, 8 liang)
Angelica sinensis root body (Danggui shen, 4 liang)
White Peony root (Baishaoyao, 2 liang, wine-stir-fried)
Winter Atractylodes rhizome (Baizhu, 4 liang, processed)
Chinese yam (Huai shanyao, 4 liang, stir-fried)
Golden Cyperus rhizome (Jin xiangfu, 2 liang, wine-stir-fried)
Selected Ginseng root (Renshen, 4 liang)
Purple quartz (Zishiying, 2 liang, vinegar-processed)
Sweet Goji berry (Gan gouqi, 4 liang)
Qicheng Mugwort leaf (Qi aiye, 2 liang, vinegar-stir-fried)
Small Ligusticum chuanxiong rhizome (Xiao chuanxiong, 2 liang)
Cook all herbs together with Placenta in aged wine until tender. Dry, roast until crisp, grind into fine powder, make pills with honey, and take 3-5 qian with warm wine.
Dual deficiency of Qi and Blood leads to a cold uterus, causing irregular Tian Gui and inability to conceive. Prepared Rehmannia nourishes Yin and generates blood; Ginseng tonifies Qi and supports Yuan Qi; Angelica nourishes blood and enriches meridians; Atractylodes strengthens Spleen to generate blood; Ligusticum moves blood sea to regulate menstruation; White Peony astringes Yin blood to harmonize collaterals; Cyperus regulates Qi and relieves depression; Chinese yam tonifies Spleen and benefits Yin; Qicheng Mugwort regulates Qi and blood to warm the blood chamber; Purple quartz astringes Qi and blood to warm the uterus; Sweet Goji nourishes the Kidney; Placenta greatly tonifies Qi and blood. Cooked in wine and formed into pills, taken with warm wine, this makes internal Qi and blood vigorous, warming the uterus and harmonizing Chong and Ren. Tian Gui regulates naturally, enabling conception.
Tiaosheng Pill
Indicated for long-term infertility, with a rapid, tight, and choppy pulse.
Prepared Rehmannia root (Shudi, 5 liang)
Angelica sinensis root (Danggui, 3 liang)
White Peony root (Baishao, 1.5 liang, wine-stir-fried)
Ligusticum chuanxiong rhizome (Chuanxiong, 1 liang)
Lycopus lucidus herb (Zelan, 2 liang)
Atractylodes macrocephala rhizome (Baizhu, 1.5 liang, stir-fried)
Dendrobium stem (Shihu, 2 liang)
Dried ginger (Ganjiang, 1 liang, stir-fried)
Moutan bark (Danpi, 1 liang, wine-stir-fried)
Cinnamon bark (Rougui, 1 liang, peeled)
Cyathula officinalis root (Yanhusuo, 2 liang, wine-stir-fried)
Grind into powder, form pills with light vinegar, and take 3 qian with warm wine.
Blood deficiency with stagnation and cold-heat imbalance causes irregular menstruation, abdominal pain, and infertility. Prepared Rehmannia nourishes Yin and generates blood; Angelica nourishes blood and enriches meridians; Ligusticum moves blood sea to regulate menstruation; White Peony astringes Yin blood to harmonize pulses; Moutan cools blood heat; Atractylodes strengthens Spleen and consolidates origin; Dendrobium tonifies deficiency and reduces heat; Dried ginger warms Stomach and dispels cold; Lycopus unblocks meridians; Cinnamon warms Ying blood; Cyathula transforms blood stasis to harmonize meridians. Vinegar pills astringe, wine administration promotes movement. Cold and heat transform simultaneously, harmonizing meridian Qi, relieving abdominal pain, and regulating Tian Gui, eliminating infertility.