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The syndrome of Huoluan (cholera-like disease with vomiting and diarrhea) is more common in summer and autumn. It arises from the invasion of wind, cold, summerheat, and heat pathogens, mixed with dietary raw and cold pathogens, which confuse and attack the interior. The healthy qi cannot withstand this, allowing the pathogens to cause chaotic disturbance, leading to the confusion of Sanjiao (Triple Burner), the interference between clear and turbid yin-yang, and disorder within the intestines and stomach. Its manifestations include vomiting, diarrhea, severe abdominal pain, and a pulse that is often fine and choppy, or deep and hidden, or large and empty. If wind pathogen is predominant, headache and aversion to cold with fever occur. If cold pathogen is predominant, muscle spasms and cold extremities occur. If summerheat pathogen is predominant, extreme thirst with excessive drinking occurs. Pathogens in the Upper Jiao result in predominant vomiting; those in the Lower Jiao result in predominant diarrhea; those in the Middle Jiao result in both severe vomiting and diarrhea. Generally, it should be treated by modifying the Zhiluan Bao'an Formula (Stabilizing and Securing Method). Add Perilla Leaf (Ziye) and Tangerine Peel (Juhong) for severe wind; add Cardamom Seed (Caodoukou) and Papaya (Mugua) for severe cold; add Reed Rhizome (Lugen) and Bamboo Shavings (Zhuru) for severe summerheat; add Coptis Rhizome (Huanglian) and Dried Ginger (Ganjiang) for severe vomiting; add Kudzu Root (Gegen) and Lotus Leaf (Heye) for severe diarrhea. If vomiting and diarrhea persist, damaging the Qi of the Middle Jiao, leading to separation of Yin and Yang, cold extremities, a faint pulse nearly imperceptible, and little desire to drink water, regardless of whether the pathogen is wind, cold, summerheat, or heat, urgently rescue with the Wanzheng Huiyang Method (Restoring Healthy Qi and Returning Yang). If there is a desire to vomit but inability to do so, and a desire to defecate but inability to do so, it is called Gan Huoluan (Dry Cholera), also known as Jiaochang Sha (Intestine-Twisting Sha). Urgently use the ancient prescription of fried salt mixed with child's urine, administered to induce vomiting, which will lead to recovery. If the tongue rolls up, sinews contract, and testicles retract into the abdomen, it is difficult to treat.

Generally, a Hongda Erhua (surging, large, and slippery) pulse in Huoluan indicates survival, while a Weise Jianchi (fine, choppy, and gradually slow) pulse indicates death.

People in the South have weak constitution. Upon occasional exposure to foul air from feces, soil, sand, and filth, they experience abdominal pain and mental restlessness, termed "Sha" (a corruption of the character "Sha" meaning sand/dust). If Sha resides in the skin and Qi level, scraping therapy is appropriate; if it resides in the muscles and Blood level, pricking therapy is appropriate; this refers to mild and superficial cases. If the condition is severe, causing bloating and obstruction in the intestines and stomach, blocking meridians, and directly attacking the heart, it may become untreatable within moments, rendering scraping and pricking ineffective; only herbal medicine can save the patient. One must know that Sha has no fixed pulse; any pulse that does not correspond to the symptoms is considered a Sha pulse. The manifestations must be distinguished: Feng Sha (Wind Sha) presents with headache, spontaneous sweating, abdominal pain, and limb numbness; Shu Sha (Summerheat Sha) presents with dizziness, excessive sweating, vomiting, diarrhea, and abdominal pain; Yin Sha (Yin Sha) presents with abdominal pain and cold limbs, also called Liang Sha (Cool Sha); Yang Sha (Yang Sha) presents with abdominal pain and warm limbs, also called Re Sha (Heat Sha). There is also Hong Sha (Red Sha), characterized by hidden red spots on the skin resembling rash, indicating Sha in the muscular exterior; Wu Sha (Black Sha), characterized by whole-body distending pain and black spots, indicating Sha toxin in the Zang-Fu organs; and Jiaochang Sha (Intestine-Twisting Sha), characterized by inability to vomit or defecate despite the urge, and severe heart and abdominal pain. Sha disease is not solely caused by the Six Qi (Six Exogenous Pathogens); it can also result from irregular diet, overwork, or invasion by foul turbidity. Generally, it should be treated with the Fangxiang Huazhuo Method (Aromatic Transformation of Turbidity). This method contains Pinellia Tuber (Banxia) and Agastache Herb (Huoxiang); do not believe quacks who claim these are contraindicated in Sha diseases. For Feng Sha, add Schizonepeta Spike (Jingjie) and Saposhnikovia Root (Fangfeng); for Shu Sha, add Talcum (Huashi) and Papaya (Mugua); for Yin Sha, add Cardamom (Doukou) and Amomum Fruit (Sharen); for Yang Sha, add Forsythia Fruit (Lianqiao) and Gardenia Fruit (Zhizi); for Hong Sha, add Burdock Fruit (Niubangzi) and Mint Herb (Bohe); for Wu Sha, add Areca Seed (Binglang) and Aurantium Fruit (Zhike); for Men Sha (Stagnant Sha), add Asarum Root (Xixin) and Platycodon Root (Jiegeng); for Jiaochang Sha, add Sandalwood Wood (Tanxiang) and Lindera Root (Wuyao). If the condition is urgent and there is no time to prepare decoctions, first administer Shayi Huichun Dan (Sha Epidemic Revival Pill).