夫寒疟之状。内经所谓先寒后热。病以时作。是也。盖伤暑汗出。腠理开发。因遇夏气。
凄
栗
方
五积散（出直指方）治感寒发疟。初作。以此解散。
苍术（炒三两） 北梗（一两） 麻黄（去根） 枳壳（制） 陈皮（各六钱） 干姜 浓
朴（制
各四
散。
每服
恒山丸（出圣惠方）治寒疟。阳虚阴盛。内外俱寒。四肢颤掉。
恒山（半两） 野狸头骨（一分） 虎头骨（一分） 猢狲头骨（一分） 天灵盖（一
分） 绿豆
末（
香（一分）
阿
二百杵。
丸如梧桐子大。修合时。勿令孝子女人见。须五月五日午时合为妙。如缓急。即不择日辰合
。未发时。以绛囊盛。于中指上系一丸。男左女右。三日不住。以热水服一丸。娠妇小儿不
可服。忌食热物。
朱砂丸（出圣惠方）治寒疟。但寒不热。四肢鼓颤不止。
朱砂（一分细研） 麝香（半分细研） 砒霜（一分细研） 恒山（一分锉） 虎头骨
（一分涂
酥炙
阿魏（一分
煮面糊和
捣一二
丸可治
吴茱萸汤（出续易简方）治寒疟先寒后热。头疼不可忍。热极即汗出。烦渴相
次。便醒。宜
吴茱萸（汤浸焙炒一两） 羌活（去芦头半两） 甘草（炙锉） 干姜（炮） 半夏（汤
洗七次
焙）
一分）
上
须
巳亥之年。当疟未发。常服暖脾胃。一方有牵牛炒半两。
养胃汤加桂（出直指方）治感发寒多热少。或但寒不热。头痛腰酸。胸满呃逆
。身体疼痛。
浓朴（制） 苍术（炒二两） 半夏（制二两） 人参 茯苓 草果 藿香（各半两） 橘
红（三分）
滓。
温服。不
雄黄丸（出圣惠方）治寒疟不止。
雄黄（一分） 硫黄（一分） 朱砂（一分） 麝香（半分） 阿魏（半分） 桂（一
分末） 干姜（一
醋煮面糊和丸。
如
草豆蔻饮（出圣济总录）治寒疟。
草豆蔻（去皮） 高良姜（半分） 恒山 青皮（汤浸去白焙） 陈皮（汤浸去白焙各
一分）
生姜
半。去
滓
正气散（出医方大成）退寒疟。止胃寒。进饮食。
藿香（四两） 草果（四两） 半夏 陈皮 浓朴 缩砂 甘草（各一两） 上锉散。
生姜枣
子煎
安息香丸（出圣惠方）治寒疟。手足鼓颤。心寒面青。
朱砂（细研） 虎头骨 猢狲头骨 砒霜 天灵盖 阿魏 安息香（各半两） 上为末。
入
朱砂
系于
槟榔汤（出圣济总录）治寒疟。
槟榔（锉） 桂（去粗皮） 恒山 陈皮（汤浸去白炒） 甘草（炙锉各半分） 上粗
末。每服
三钱
神效方（出圣惠方）治寒疟。
砒霜（一两酸浆一碗于日未出时慢火熬如稀糊便入药） 朱砂（细研） 白芥子 阿魏
（各
一钱）
至
十丸。
分利元散（出医方集成）治体虚之人患疟。寒多。不可服截药者。
川乌 附子（各一两） 南星（二两） 木香（五钱别锉临时入） 上除木香不见火外。
余味
各将
当
白芥子丸（出圣惠方）治寒疟。手足鼓颤。心寒面青。
白芥子 朱砂（细研） 阿魏 恒山（各等分） 上为末。入朱砂研匀。醋煮面糊和丸。
如
桐子
阿魏丸（出圣惠方）治寒疟。
砒霜 朱砂 阿魏 麝香（各一分） 上同研如粉。面糊和丸。如小豆大。每于未发前。
冷醋
猪胆膏（一名二姜散出朱氏集验方）治脾胃虚弱。遂成疟疾。寒多热少。大概
寒发于胆。猪
仍治秋深寒疟。
干姜（炮一两） 良姜（切小块麻油炒干一两一方各二两半炒半生不用麻油炒） 上为
末。
分作
十
致仕
果附汤（出医方集成）治气虚脾寒。疟疾不愈。振寒少热。面青。或单寒者。
或大便涩。小
草果仁 附子（炮去皮脐） 上等分。 咀。每服半两。水二钟。姜七片、枣二枚。煎
七
分
七枣汤（一名乌头七枣汤）治疟及久疟但寒。并脾寒发疟。
用川乌一只热多寒少者汤泡七次。寒多热少者火炮七次。切去皮焙干。分二服。水一碗
半。
枚炮
附
散其热性。服之必效。经验方陈氏云。林侍郎谦之。常以此药授人。余家服屡有效。
生熟附子汤 分利阴阳。止发热寒。治疟疾欲作。胸痞痰呕。头眩颤掉。
用附子二枚。一生去皮。一盐汤浸去皮炮。各取二钱。加沉香木香少许。水一盏。姜七
片、
鳖甲散 治寒疟、痨疟。
取鳖甲不拘多少。醋炙黄为末。每服二钱。温酒调下。空心食前临卧时各一服。治痨疟。
涂
鳖甲汤 治疟寒多。
鳖甲（汤浸刮令净醋炙） 常山 柴胡 桂（去皮各一两） 白术（一两） 牡蛎（半
两火煨
赤）
温脾饮 治寒疟。兼脾久湿。上焦噎塞不通。止渴进饮食。
真陈橘皮（五个去瓤） 乌梅（十个） 人参（一分） 大枣子（二十个） 甘草（五
寸） 草果
子（
煎
一
蒜丹 寒疟手足鼓颤。心寒面青。宜用此方。
独蒜（一枚） 黄丹（半两） 上件药相和。五月五日午时同捣一千杵。丸如黑豆大。
未发
时。
乌头丸 先寒后热者。名之为寒疟。故寒而不热。面色黑者。名为厥疟。先寒后热
。热少寒
瘥。莫服汤。
草乌头（削去皮） 用沸汤炮一十四度。以盏盖之。薄切焙干。为末。稀糊和丸。如桐
子
大。
疟只
蒜丸子 治寒多热少。
良姜 浓朴 附子（各三钱） 上为末。大蒜丸。于发日绝早。煎乌梅汤。匀作三服。
早
食前
[Chills Malaria (with Discussion)]
The symptoms of Chills Malaria are as described in the *Neijing* (*Inner Canon*): chills precede fever, and the illness occurs at regular intervals. This is likely caused by contracting summerheat with sweating, leading to the opening of the Couli (skin pores), followed by an invasion of summer cold.
Wuji San (Five Accumulations Powder) [from *Zhizhi Fang*]: Treats malaria induced by cold contraction. Use this formula to dissipate the pathogen at the initial stage.
Ingredients: Cangzhu (Atractylodis Rhizoma, stir-fried, 3 liang), Beigeng (Platycodonis Radix, 1 liang), Mahuang (Ephedrae Herba, roots removed), Zhike (Aurantii Fructus, processed), Chenpi (Citri Reticulatae Pericarpium, each 6 qian), Ganjiang (Zingiberis Rhizoma, dried), Houpo (Magnoliae Officinalis Cortex, processed, each 4 liang). The above ingredients are crushed into a coarse powder. Take 3 qian per dose, add 1 zhan of water and 5 slices of fresh ginger, decoct until 0.7 zhan remains, remove the dregs, and take warm.
Hengshan Wan (Dichroa Pill) [from *Shenghui Fang*]: Treats Chills Malaria characterized by Yang deficiency and Yin excess, internal and external coldness, and trembling of the four limbs.
Ingredients: Hengshan (Dichroae Radix, 0.5 liang), Yeli Tougu (Bone of Wild Cat Head, 1 fen), Hutougu (Tiger Bone, 1 fen), Husun Tougu (Monkey Head Bone, 1 fen), Tianlinggai (Skull Cap of Human, 1 fen), Ludoumo (Mung Bean Powder, 1 fen), Shexiang (Moschus, 1 fen). Grind the above ingredients finely, add Awei (Ferulae Resina, 1 fen), and pound together for 200 strokes. Form pills the size of Sophora seeds. During preparation, avoid letting filial children and women see it. It is best to prepare on the 5th day of the 5th lunar month at Wu hour (noon). In emergencies, do not select specific dates. Before the onset of the attack, place one pill in a crimson pouch and tie it to the middle finger; males on the left hand, females on the right hand. Wear continuously for three days without removal. Take one pill with hot water when the attack begins. Contraindicated in pregnant women and children. Avoid hot foods.
Zhusha Wan (Cinnabar Pill) [from *Shenghui Fang*]: Treats Chills Malaria characterized by chills only without fever, and continuous trembling of the four limbs.
Ingredients: Zhusha (Cinnabaris, 1 fen, finely ground), Shexiang (Moschus, 0.5 fen, finely ground), Pishuang (Arsenic Trioxide, 1 fen, finely ground), Hengshan (Dichroae Radix, 1 fen, chopped), Hutougu (Tiger Bone, 1 fen, coated with butter and roasted), Awei (Ferulae Resina, 1 fen, boiled with wheat paste). Pound 100-200 times to form pills.
Wuzhuyu Tang (Evodia Decoction) [from *Xu Yi Jian Fang*]: Treats Chills Malaria with chills preceding fever, unbearable headache, sweating at peak heat, followed by irritability and thirst, waking up after sweating.
Ingredients: Wuzhuyu (Evodiae Fructus, soaked in water, baked, and stir-fried, 1 liang), Qianghuo (Notopterygii Rhizoma et Radix, de-rhizome, 0.5 liang), Gancao (Glycyrrhizae Radix et Rhizoma, honey-fried and chopped), Ganjiang (Zingiberis Rhizoma, processed), Banxia (Pinelliae Rhizoma, washed seven times in water, baked). Crush the ingredients, add 2 zhong of water and 7 slices of fresh ginger, decoct until 0.7 zhan remains, remove dregs, and take warm. For preventive use in Si or Hai years before malaria onset to warm the Spleen and Stomach. One variation includes fried Niutou (Pharbitidis Semen, 0.5 liang).
Yangwei Tang Plus Guizhi [from *Zhizhi Fang*]: Treats malaria induced by exogenous pathogens with more chills than fever, or chills only without fever, accompanied by headache, sore waist, chest fullness, hiccups, and body pain.
Ingredients: Houpo (Magnoliae Officinalis Cortex, processed), Cangzhu (Atractylodis Rhizoma, stir-fried, 2 liang), Banxia (Pinelliae Rhizoma, processed, 2 liang), Renshen (Ginseng Radix et Rhizoma), Fuling (Poria), Caoguo (Tsaoko Fructus), Huoxiang (Agastaches Herba, each 0.5 liang), Juhong (Citri Reticulatae Pericarpium Rubrum, 3 qian). Crush the ingredients, add 3 zhan of water and 5 slices of fresh ginger, decoct until 1 zhan remains, remove dregs, and take warm. Take as needed.
Xionghuang Wan (Realgar Pill) [from *Shenghui Fang*]: Treats persistent Chills Malaria.
Ingredients: Xionghuang (Realgar, 1 fen), Liuhuang (Sulfur, 1 fen), Zhusha (Cinnabaris, 1 fen), Shexiang (Moschus, 0.5 fen), Awei (Ferulae Resina, 0.5 fen), Guizhi (Cinnamomi Ramulus, 1 fen, powdered), Ganjiang (Zingiberis Rhizoma, 1 fen). Mix with vinegar-boiled wheat paste to form pills. Size of Sophora seeds. Take 3 pills per dose with warm water.
Caodoukou Yin (Cardamom Drink) [from *Shengji Zonglu*]: Treats Chills Malaria.
Ingredients: Caodoukou (Alpiniae Katsumadai Fructus, peeled), Gaoliangjiang (Galangal Root, 0.5 fen), Hengshan (Dichroae Radix), Qingpi (Citri Reticulatae Pericarpium Viride, soaked in water, de-white, baked), Chenpi (Citri Reticulatae Pericarpium, soaked in water, de-white, baked, each 1 fen), Shengjiang (Fresh Ginger, half piece). Crush the ingredients, add 1 zhan of water, decoct until 0.7 zhan remains, remove dregs, and take warm.
Zhengqi San (Righteous Qi Powder) [from *Yifang Dacheng*]: Disperses Chills Malaria, stops Stomach cold, promotes appetite.
Ingredients: Huoxiang (Agastaches Herba, 4 liang), Caoguo (Tsaoko Fructus, 4 liang), Banxia (Pinelliae Rhizoma), Chenpi (Citri Reticulatae Pericarpium), Houpo (Magnoliae Officinalis Cortex), Suosha (Amomi Fructus Rotundus), Gancao (Glycyrrhizae Radix et Rhizoma, each 1 liang). Crush into a coarse powder. Take 3 qian per dose, decoct with fresh ginger and jujubes, and take the liquid.
Anshixiang Wan (Styrax Pill) [from *Shenghui Fang*]: Treats Chills Malaria with trembling of hands and feet, cold heart, and blue complexion.
Ingredients: Zhusha (Cinnabaris, finely ground), Hutougu (Tiger Bone), Husun Tougu (Monkey Head Bone), Pishuang (Arsenic Trioxide), Tianlinggai (Skull Cap of Human), Awei (Ferulae Resina), Anshixiang (Styrax, each 0.5 liang). Grind all ingredients into fine powder, mix with finely ground Cinnabar. Mix with vinegar-boiled wheat paste to form pills the size of Sophora seeds. Take 5 pills per dose with warm water. Tie the pill to the middle finger, male left, female right, wear for three days continuously.
Bolang Tang (Areca Decoction) [from *Shengji Zonglu*]: Treats Chills Malaria.
Ingredients: Banglang (Arecae Semen, chopped), Guizhi (Cinnamomi Ramulus, de-bark), Hengshan (Dichroae Radix), Chenpi (Citri Reticulatae Pericarpium, soaked in water, de-white, stir-fried), Gancao (Glycyrrhizae Radix et Rhizoma, honey-fried and chopped, each 0.5 fen). Crush into coarse powder. Take 3 qian per dose, add 1 zhan of water and 3 slices of fresh ginger, decoct until 0.7 zhan remains, remove dregs, and take warm.
Shenxiao Fang (Miraculous Formula) [from *Shenghui Fang*]: Treats Chills Malaria.
Ingredients: Pishuang (Arsenic Trioxide, 1 liang, boiled slowly in 1 bowl of sour bean juice before sunrise until thick paste, then mixed with herbs), Zhusha (Cinnabaris, finely ground), Baijiezi (Brassicae Semen Album), Awei (Ferulae Resina, each 1 qian). Mix and form pills. Take 10 pills per dose with warm water.
Fenli Yuan San (Separating and Benefiting Primordial Powder) [from *Yifang Jicheng*]: Treats malaria in deficient individuals with predominant chills, where antiperiodic drugs cannot be used.
Ingredients: Chuanwu (Aconiti Radix Lateralis Preparata), Fuzi (Aconiti Radix Preparata, each 1 liang), Nanxing (Arisaematis Rhizoma, 2 liang), Muxiang (Aucklandiae Radix, 5 qian, separately chopped for immediate addition). Except for Muxiang, process other ingredients avoiding direct fire. Take before the malaria attack.
Baijiezi Wan (White Mustard Seed Pill) [from *Shenghui Fang*]: Treats Chills Malaria with trembling of hands and feet, cold heart, and blue complexion.
Ingredients: Baijiezi (Brassicae Semen Album), Zhusha (Cinnabaris, finely ground), Awei (Ferulae Resina), Hengshan (Dichroae Radix, equal parts). Grind into fine powder, mix thoroughly with Cinnabar. Mix with vinegar-boiled wheat paste to form pills the size of Sophora seeds. Take 5 pills per dose with warm water.
Awei Wan (Ferula Pill) [from *Shenghui Fang*]: Treats Chills Malaria.
Ingredients: Pishuang (Arsenic Trioxide), Zhusha (Cinnabaris), Awei (Ferulae Resina), Shexiang (Moschus, each 1 fen). Grind together into powder. Mix with wheat paste to form pills the size of small beans. Take before the onset of the attack with cold vinegar.
Zhudan Gao (Pig Gallbladder Paste, also known as Erjiang San) [from *Zhushi Jiyan Fang*]: Treats malaria resulting from Spleen and Stomach weakness, with more chills than fever. Cold typically originates from the Gallbladder. Pig gallbladder guides the medicine to the Gallbladder. Also treats late autumn Chills Malaria.
Ingredients: Ganjiang (Zingiberis Rhizoma, processed, 1 liang), Liangjiang (Galangal Root, cut into small pieces, stir-fried in sesame oil until dry, 1 liang; another version uses 2.5 liang each, half stir-fried half raw, no sesame oil). Grind into powder. Divide into ten doses. Take one dose mixed with pig gallbladder juice.
Zhishi Guofu Tang [from *Yifang Jicheng*]: Treats Qi deficiency and Spleen cold, persistent malaria, shivering with slight fever, blue complexion, or chills only, constipation, and clear urine.
Ingredients: Caoguoren (Tsaokocarpium Semen), Fuzi (Aconiti Radix Preparata, peeled and de-navel). Equal parts. Crush. Take 0.5 liang per dose, add 2 zhong of water, 7 slices of fresh ginger, and 2 jujubes, decoct until 0.7 zhan remains, remove dregs, and take warm.
Qizao Tang (Seven Jujube Decoction, also known as Wutou Qizao Tang) [from *Yifang Jicheng*]: Treats malaria and chronic malaria with chills only, and Spleen cold-induced malaria.
Usage: Use one Chuanwu (Aconiti Radix Lateralis Preparata). If heat predominates over chills, soak in water seven times; if chills predominate over heat, roast over fire seven times. Peel, bake dry, and divide into two doses. Add 1.5 zhan of water and 7 jujubes, decoct together. Prepared Aconite disperses its heat nature; efficacy is assured. Empirical formula by Chen Shi: Vice Minister Lin Qianzhi often gave this prescription to others. My family has used it with frequent success.
Shengshu Fuzi Tang (Raw and Processed Aconite Decoction): Balances Yin and Yang, stops fever and chills, treats impending malaria with chest oppression, phlegm, vomiting, dizziness, and tremors.
Usage: Use two Fuzi (Aconiti Radix Preparata). One raw, peeled; one soaked in salt water, peeled, and processed. Take 2 qian of each. Add a little Chenxiang (Aquilariae Lignum Resinatum) and Muxiang (Aucklandiae Radix). Add 1 zhan of water, 7 slices of fresh ginger, and 2 jujubes, decoct until 0.7 zhan remains, remove dregs, and take warm.
Biejia San (Softshell Turtle Shell Powder) [from *Yifang Jicheng*]: Treats Chills Malaria and Lao Malaria (consumptive malaria).
Usage: Take Biejia (Trionycis Carapax et Plastrum) in any amount. Roast with vinegar until yellow, grind into powder. Take 2 qian per dose, mixed with warm wine. Take once when empty-stomached, once before meals, and once before bed. Treats Lao Malaria.
Biejia Tang (Softshell Turtle Shell Decoction) [from *Yifang Jicheng*]: Treats malaria with predominant chills.
Ingredients: Biejia (Trionycis Carapax et Plastrum, soaked in water, scraped clean, vinegar-roasted), Changshan ( Dichroae Radix), Chaihu (Bupleuri Radix), Guizhi (Cinnamomi Ramulus, de-bark, each 1 liang), Baizhu (Atractylodis Macrocephalae Rhizoma, 1 liang), Muli (Ostreae Concha, 0.5 liang, fire-roasted red). Crush ingredients, add 3 zhan of water, decoct until 1 zhan remains, remove dregs, and take warm.
Wenpi Yin (Warm Spleen Drink) [from *Yifang Jicheng*]: Treats Chills Malaria. Also treats long-standing Spleen dampness, upper Jiao obstruction, thirst, and poor appetite.
Ingredients: Zhen Chenpi (True Citri Reticulatae Pericarpium, 5 pieces, de-pith), Wumei (Mume Fructus, 10 pieces), Renshen (Ginseng Radix et Rhizoma, 1 fen), Dazao (Jujubae Fructus, 20 pieces), Gancao (Glycyrrhizae Radix et Rhizoma, 5 cun), Caoguo (Tsaoko Fructus, 3 pieces). Crush ingredients, add 3 zhan of water, decoct until 1 zhan remains, remove dregs, and take warm.
Suan Dan (Garlic and Minium Pill) [from *Yifang Jicheng*]: Treats Chills Malaria with trembling of hands and feet, cold heart, and blue complexion.
Ingredients: Dusuan (Single Clove Garlic, 1 bulb), Huangdan (Minium, 0.5 liang). Mix ingredients, pound together for 1000 strokes on the 5th day of the 5th lunar month at Wu hour (noon). Form pills the size of black beans. Take before the onset of the attack.
Wutou Wan (Aconite Pill) [from *Yifang Jicheng*]: Chills preceding fever is named Chills Malaria, characterized by chills only without fever. Black complexion with chills preceding fever and less fever is named Jue Malaria. After recovery, do not take decoctions.
Ingredients: Caowutou (Aconiti Kusnezoffii Radix, peeled). Process 14 times in boiling water, cover with a cup, slice thinly, bake dry, and grind into powder. Mix with thin paste to form pills the size of Sophora seeds. Take 3 pills per dose with warm water. Do not take excessively immediately after malaria subsides.
Suanwan Zi (Garlic Pill) [from *Yifang Jicheng*]: Treats predominant chills and slight fever.
Ingredients: Liangjiang (Galangal Root), Houpo (Magnoliae Officinalis Cortex), Fuzi (Aconiti Radix Preparata, each 3 qian). Grind into powder, shape into garlic-shaped pills. On the morning of the attack day, decoct Wumei (Mume Fructus) soup, divide evenly into three doses. Take before breakfast.