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Li Zhai stated: In patients with sores and ulcers, if there is dribbling, frequent urination, or a涩 (astringent/obstructive) sensation in the urethra, this is an ominous sign of kidney meridian deficiency. It is appropriate to use Jiajian Bawei Wan (Modified Eight-Ingredient Pill) to tonify yin. If the lower legs and shins are cold in reverse, it is appropriate to use Bawei Wan (Eight-Ingredient Pill) to tonify yang. If urination is frequent and yellow, it is appropriate to use Siwu Tang (Four Substances Decoction) added with Renshen (Ginseng), Baizhu (Atractylodes Macrocephala Rhizome), Maidong (Ophiopogon Tuber), and Wuweizi (Schisandra Fruit) to nourish the lung and kidney. If urine volume is short and scanty, it is appropriate to use Buzhong Yiqi Tang (Tonify the Middle and Augment the Qi Decoction) added with Shanyao (Dioscorea Rhizome), Maidong, and Wuweizi to tonify the spleen and lung. If heat accumulation in the bladder causes difficulty in urination, it is appropriate to use Wulin San (Five Strangury Powder) to clear heat. If dryness and heat in the spleen qi prevent proper transformation, it is appropriate to use Huangqin Qingfei Yin (Scutellaria Lung-Clearing Infusion) to nourish yin. If bladder yin is deficient such that yang cannot be generated, it is appropriate to use Zishen Wan (Kidney-Nourishing Pill). If bladder yang is deficient such that yin cannot be transformed, it is appropriate to use Liuwei Dihuang Wan (Six-Ingredient Rehmannia Pill). Diseases caused by kidney deficiency often transmit to this syndrome; without nourishing the source of transformation, rescue is impossible. Using Huangbai (Phellodendron Bark) and Zhimu (Anemarrhena Rhizome) would instead drain yang, thereby hastening the danger. In elderly men with impotence who indulge in sexual desire, causing internal depletion of essence and qi, resulting in penile pain and difficult urination, Jiajian Bawei Wan added with Cheqianzi (Plantago Seed) and Niuxi (Achyranthes Root) should be used. If ineffective, add Fuzi (Prepared Aconite Root); many cases recover. If essence is already exhausted but further depleted, causing pulling pain during defecation and urination—where greater pain leads to more urge to defecate/urinate, which in turn increases pain—using the previous formula with added Fuzi has also led to recovery. Wang Taipu said: Without yin, yang cannot be transformed; without yang, yin cannot be generated. One must nourish the source of transformation. If one uses only bland and diuretic agents, it will further damage true yin, thereby hastening the danger.

Li Zhai stated: Spasm (Jing Syndrome) occurring in patients with sores and ulcers is due to deficiency of qi and blood, invasion by external pathogens, or internal deficiency with stagnant fire. The manifestations include tightness of the jaw, stiffness and rigidity of the four limbs, opisthotonos (backward arching of the back), and limb convulsions. Cases with sweating but no aversion to cold are called Rou Jing (Soft Spasm). Wind disperses qi, hence sweating occurs. Cases with no sweating and aversion to cold are called Gang Jing (Hard Spasm). Cold congeals blood, hence no sweating occurs. All these arise from excessive loss of blood, leaving tendons without nourishment. Thus, they are commonly seen after excessive sweating or purgation in Taiyang disease, or in patients with chronic ulcers and postpartum women; these are signs of collapse. If qi and blood are greatly tonified, many cases can be treated; if treated as wind disorders, it will hasten the danger. The theories and methods regarding spasm are detailed in "Miscellaneous Disorders Treatise," Volume 12, Chapter on Spasm Syndrome, and should be consulted.