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It is produced by refining Mercury (Shuiyin, 水银). Nowadays, people often adulterate it with Minium (Huandan, 黄丹) and Alum Red (Fan Hong, 矾红); this must be known.

Pungent, warm, toxic. Breaks up stagnation, attacks phlegm-saliva, dissipates chest nodules, kills insects and lice. Treats tinea and malignant sores.

Hupo Gao (Amber Ointment): Guan Fen (Lead Subacetate Powder, 官粉) 1 qian, Xue Yu (Burnt Human Hair, 血余) 1 qian, Qing Fen (Calomel, 轻粉) 5 fen, Yin Zhu (Cinnabar Substitute/Red Lead, 银朱) 7 fen, Hua Jiao (Sichuan Pepper, 花椒) 7 grains, Huang La (Yellow Beeswax, 黄蜡) 4 qian, Hu Po (Amber, 琥珀) 1 fen, Xiang You (Sesame Oil, 香油) 1 liang. Fry the Xue Yu and Hua Jiao until charred, remove the dregs, then add the various powders, and finally add the Huang La. Used to treat ulcerated carbuncles on fingers. Additionally, Bai Ji powder mixed with Yin Zhu, applied externally with cold water.

Those that are red like a rooster's comb, bright and clear without odor, and heavy in weight are of good quality. Inferior ones are called "Xun Huang" (Smoked Realgar), which smell when burned and can only be used to kill insects/lice or fumigate tinea.

Pungent, warm, toxic. Kills hundred poisons and wards off evil, treats convulsions and epilepsy while killing parasites. Disperses severe wind affecting all joints, resolves diarrhea and dysentery caused by latent summerheat. Opens phlegm obstruction and searches out wind, stops abdominal pain and breaks up accumulation. Eliminates vertigo caused by head wind, relieves chills and fever of malaria, transforms blood stasis in the abdomen, simultaneously kills tuberculosis worms and childhood malnutrition worms, removes nasal polyps, and cures malignant sores. Mouse-dropping shaped Realgar is best; for tinea, it is most effective.

Grows in the valleys of Wudu. Those transparent like a rooster's comb are excellent; those with no odor and solid texture are good. Nowadays, people often use this to fake Cinnabar (Dansha, 丹砂); this must be known. For She Tou Ding (Snake-head Carbuncle), She Yan Ding (Snake-eye Carbuncle), She Jie Ding (Snake-joint Carbuncle), She Bei Ding (Snake-back Carbuncle), She Fu Ding (Snake-belly Carbuncle), and Ni Qiu Ding (Loach Carbuncle), use Xiong Huang (Realgar) 2 qian, Qing Fen (Calomel) 5 fen, Chan Su (Toad Venom, 蟾酥) 2 qian, Bing Pian (Borneol, 冰片) 1 fen, mix with water and apply externally.

For sudden possession by evil spirits, grind into powder and insufflate into the nose. (Verified Formula No. 1.)

To ward off nightmares, carry a date-sized piece under the left armpit for life to prevent nightmares. (No. 2.)

For lower body pain and itching, parasitic erosion, and Huhuo disease, burn to smoke and fumigate inside a bottle. (No. 3.)

For Wu Shi Zhu Disease (Five Corpse Transmission Disease), which presents with unpredictable pain shooting up to the heart and hypochondrium, combine with Garlic Pills the size of a bullet, take one pill with wine each time. (No. 4.)

For epigastric and hypochondriac masses, use 1 liang of Xiong Huang and 1 liang of Bai Fan (Alum), make a paste with flour dough and apply as a patch; recovery occurs when stool becomes heavy. (No. 5.)

For genital swelling like a beanbag with severe pain, combine with Bai Fan 2 liang per 2 liang, Gan Cao (Licorice Root, 甘草) 1 liang, decoct in water and soak the affected area. (No. 6.)

For chronic non-healing sores, use 2 qian of Xiong Huang and 5 qian of Chen Pi (Tangerine Peel, 陈皮), roll in green cloth, burn to produce smoke for fumigation; when hot fluid flows out, repeated applications will cure it. (No. 7.)

For foul-smelling, rotting gums, known as Zou Ma Ya Gang (Running Horse Gum Disease), take 7 dates pitted, wrap each with Xiong Huang the size of a soybean, pierce with iron wire, burn over a lamp to ash, and sprinkle on the lesion. (No. 8.)

For parasitic erosion of the nose, combine with Ting Li powder (Descurainia Seed, 葶苈) and Pig Bile, apply using a Sophora branch. (No. 9.)

For reddish nose tip, combine with Liu Huang (Sulfur, 硫黄) 5 qian each, Guan Fen (Lead Subacetate Powder) 2 qian, mix with milk and apply externally. (No. 10.)

For toothache caused by worms, combine with date flesh to form pills, insert into the cavity. (No. 11.)

For Dou Ding (Smallpox Carbuncle), use 1 qian of Xiong Huang and 3 qian of Zi Cao (Arnebia Root, 紫草), grind to powder, mix with Carthamus juice (Zhi Zi Juice, 胭脂汁), puncture the carbuncle with a needle and apply. (No. 12.)

For insects crying within the skin, moving like crabs, transformed from muscle and flesh, combine with Lei Wan (Wormwood Fruit, 雷丸) powder, sprinkle on pork, roast thoroughly and eat. (No. 13.)

For swelling and pain from beating wounds, combine with Mi Tuo Seng powder (Litharge, 密陀僧) and water, apply externally. (No. 14.)

For wind-induced itching feeling like crawling insects, combine with Song Xiang (Rosin, 松香) powder, honey-form pills the size of beans, take 10 pills three times daily, curable in 100 days. (No. 15.)

For traditional Chinese medicine arrow poison, apply powder externally; recovery follows sweating. (No. 16.)

For critical hiccups, decoct 2 qian of Xiong Huang in yellow wine, inhale the vapor to stop immediately. (No. 17.)

For Tian She Du (Herpes Zoster/Shingles), Mu Li Fen (Oyster Shell Powder, 牡蛎粉) 2 qian, Xiong Huang 4 qian, mix with honey and apply externally. (No. 18.)

For food poisoning, combine with Qing Dai powder (Indigo Naturalis, 青黛), swallow with fresh well water. (No. 19.)

Jie Nue Wan (Malaria-Cutting Pill): Xin Shi (Arsenolite, 信石) 1 qian, Ming Xiong Huang (Clear Realgar, 明雄黄) 3 qian, Chen Sha (Cinnabar, 辰砂) 3 qian, Gan Cao (Licorice Root) 2 qian, Lv Dou Fen (Mung Bean Powder, 绿豆粉) 1 liang. Form pills the size of beans. On the morning of malaria onset (at wu geng/early dawn), swallow two pills with well water. Children take one pill. Malaria with deep pulse can be cut off. (First among Various Formulas.)