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It is not considered "late" until a long time has passed; rather, the period after the current day belongs to the Yin phase. The application of purgation (Purgative method) refers to its use in the preceding Yang phase. Therefore, it is said that purgation is never too late, and one should not disdain using it late. This constitutes skillful adherence to pathological principles. Perspiration inherently causes the loss of Yin fluids, as excessive sweating leads to Yang Qi following the Yin fluids outwards. Purgation inherently drains Yang Qi, as excessive purgation leads to Yin fluids following the Yang Qi outwards. Thus, it is said that excessive sweating causes the collapse of Yang, while excessive purgation causes the collapse of Yin.

If one errs by inducing excessive perspiration, blood stasis accumulates in the Upper Jiao, resulting in epistaxis (nosebleed).
If one errs by inducing excessive diuresis, blood stasis accumulates in the Lower Jiao, resulting in mania (the patient exhibits behavior resembling madness).

In Shanghan disease, if the pulse at both Cun and Chi positions is elongated, accompanied by profuse spontaneous sweating and a body surface cold as ice or stone, yet the pulse entering the interior becomes fine and small while the patient's movements remain normal, this indicates the transmission of Yangming pathogen into Shaoyin. This corresponds to the combination of Wu and Gui, analogous to the husband transmitting to the wife. (The primary formula is: Baihu Jia Guizhi Tang [White Tiger plus Cinnamon Twig Decoction]). However, although the pulse is fine and small, it must be distinguished by its rate (rapid vs. slow). In this syndrome, the pulse is rapid rather than slow; therefore, this method is employed.

For the treatment of the elderly, children, and those with deficiency constitutions suffering from Shanghan for five to six days, presenting with mental confusion, delirious speech, or dysuria (scanty or painful urination), restlessness without proper rhythm, or irritability with insomnia, all these conditions are suitable for this prescription.

When injured by heat due to exertion, Heart Fire flares excessively and Lung Qi is entirely deficient, resulting in a洪大 (surging-large) pulse. When exertion causes Fire to prevail, it signifies that Heat has damaged Qi. (The primary formula is: Baihu Jia Renshen Tang [White Tiger plus Ginseng Decoction]. Laborers often suffer from this; this must be known.)

When injured by heat due to stillness, Fire attacks the position of Metal (Lung), causing Lung Qi to escape outward, resulting in aversion to cold and a deep, rapid pulse. When stillness causes Dampness to prevail, the body feels heavy. (The primary formula is: Baihu Jia Cangzhu Tang [White Tiger plus Atractylodes Macrocephala Decoction]. People living in leisure often suffer from this; this must be known.]
Taking Baihu Tang in spring would drain Metal (Lung); taking Chaihu Tang in autumn would drain Wood (Liver).
This discusses the constant state of the body constitution.

Fan (Vexation) pertains to Qi, while Zao (Restlessness) pertains to Blood. Qi is governed by the Lung, and Blood by the Kidney. Therefore, Zhizi (Gardeniae Fructus) is used to treat Lung-related Fan, and Xiangchi (Fermented Soybean) is used to treat Kidney-related Zao. Vexation and restlessness involve inner chagrin and inability to sleep.
For cases with shortness of breath and empty fullness, add Gancao (Licorice Root). For cases with vomiting or hiccups, add Shengjiang (Fresh Ginger) and Ju Pi (Citrus Reticulata Pericarpium). For abdominal fullness and vexation after purgation, use Zhizi Houpo Zhishi Tang [Gardenia, Magnolia Bark, and Immature Bitter Orange Decoction].
For slight fever and vexation after purgation, use Zhizi Gancao Ganjiang Tang [Gardenia, Licorice, and Dried Ginger Decoction].