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Huangdi asked: Do a person's living environment, activity level, and courage or timidity also cause changes in the pulse? Qibo replied: All instances of fright, anger, fatigue, movement, and stillness among people result in such changes. Therefore, walking at night causes panting originating from the Kidney channel, with pathogenic qi overflowing to damage the Lung; falling from a height or experiencing fright causes panting originating from the Liver channel, with pathogenic qi overflowing to harm the Spleen; sudden fright or terror causes panting originating from the Lung channel, with pathogenic qi overflowing to injure the Heart; wading through water or suffering falls causes panting originating from the Kidney and bones. At such times, those who are courageous have smooth Qi circulation and recover quickly, while those who are timid suffer from lingering pathogens that cause disease. Thus it is said: The way to diagnose disease lies in observing a patient's courage or timidity, the strength of their sinews and bones, and the condition of their skin, thereby understanding their condition as a diagnostic method.

This passage states that the Seven Emotions (Joy, Anger, Worry, Thought, Sadness, Fear, Fright) and physical overexertion all disturb the mind and body. Those with strong constitution have smooth Qi and Blood circulation and soon return to harmony without illness; those with weak constitution suffer from stagnant Qi and Blood, leading to disease. Therefore, in clinical practice, one must observe the strength of the patient's form and Yuan Qi (Original Qi), investigate the origin of the disease, which is a crucial method for seeking medical treatment.

Thus, excessive fullness from eating causes sweat to emerge from the Stomach; fright causing depletion of Jing (Essence) causes sweat to emerge from the Heart; carrying heavy loads and traveling far causes sweat to emerge from the Kidney; running fast and feeling fear causes sweat to emerge from the Liver; bodily shaking and arduous labor causes sweat to emerge from the Spleen. Therefore, diseases arising from Yin-Yang imbalance across the four seasons of Spring, Summer, Autumn, and Winter all stem from overuse, which is the normal pattern.

The Classics state: "Those who have lost blood should not be sweated; those who have suffered excessive sweating should not have blood let." This indicates that Sweat and Blood are both transformed from the essence of water and grain, originating from the same source. When labor or injury disturbs the essence of the Five Zang Organs, it combines with the essence of water and grain in the Stomach, ascends with Qi to the Lung, transforms into sweat, and leaks out through the skin and interstices. Hence, diseases of Yin-Yang and Qi-Blood arising in the four seasons all result from mental and physical overexertion, which is the normal pattern.

In *Ling Shu: Da Huo Lun*, Huangdi asked: What causes a person to be prone to forgetfulness? Qibo answered: Insufficiency of Upper Qi, excess of Lower Qi, fullness of the Intestines and Stomach, and deficiency of the Heart and Lungs. Due to this deficiency, Ying Qi (Nutritive Qi) and Wei Qi (Defensive Qi) remain stagnant in the lower part, and after a long time fail to ascend when they should, thus causing forgetfulness.

Forgetfulness, known in later generations as Jian Wang (Impaired Memory), occurs because the Clear Yang Qi of the Heart and Lung is deficient, causing the Shen (Spirit) to lack clarity and resulting in forgetfulness. When Clear Yang is deficient in the upper part, Turbid Yin fails to descend, leading to fullness in the Intestines and Stomach. The Fu organs fail to transform and move, causing Ying and Wei Qi to stagnate in the lower part and fail to ascend. Since the Heart governs Ying Qi and the Lung governs Wei Qi, their Qi fails to ascend on time, resulting in deficiency of the Heart and Lung and consequently forgetfulness.