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Tianpao Chuang (Heavenly Blister), resembling water blisters, has thin and lustrous skin. It may appear on the head and face or spread over the entire body. This condition is caused by epidemic pathogens leading to hyperactivity of Shaoyang Ministerial Fire (Shaoyang Xianghuo, fire associated with the Shaoyang channel often linked to metabolic heat), hence the name Tianpao. It results from Wind-Heat pathogenic factors lodging between the skin layers; unable to vent outward, they cause the blood to boil and heat up, condensing into blisters. Treatment should focus on Clearing Heat and Cooling Blood (Qingre Liangxue); once the Heat is resolved, the condition heals. If accompanied by exterior pathogens manifesting as fever and a rapid pulse, Jingfang Baidu San (Jingfang Decoction for Resisting Toxins) is indicated. If Fire is excessive, herbs such as Huangqin (Scutellariae Radix), Lianqiao (Forsythiae Fructus), Jinyinhua (Lonicerae Japonicae Flos), and Yuanshen (Scrophulariae Radix) may be added. If swelling and pain are present with a rapid pulse and constipation, this indicates excess in both the interior and exterior; Fangfeng Tongsheng San (Fangfeng Decoction for Unblocking and Assisting Health) is suitable for resolving both exterior and interior excesses. If there is abundant discharge of toxic fluid externally, Jinhuang San (Golden Yellow Powder) can be applied topically, or Shizhen San (Stone Treasure Powder) sprinkled; all cases will heal.

Fanhuai Chuang (Flower-Reversing Sore) arises after ulceration, caused by Liver Fire and dry Blood generating Wind. Exophytic tissue may protrude from the wound like a mushroom, varying in size, or resemble a snake's head, varying in length. Rubbing or damaging it causes fresh blood to flow, and prolonged duration leads to deficiency in the person. The treatment method should nourish the Liver and nourish Blood, such as using Zhizi Qinggan Tang (Gardenia Decoction for Clearing the Liver). Topically applying Lizhi Gao (Veratrum Ointment, a formula by Zhang Jingyue) will cause the exophytic tissue to retract, but this must be done only when Yuanqi (Primal Qi) has gradually recovered and pus/toxins are nearly exhausted; otherwise, retraction followed by recurrent ulceration occurs. Misuse of knives, needles, caustic medicines, or moxibustion will exacerbate the condition, potentially causing uncontrollable bleeding and symptoms such as chills, high fever, and vomiting. In such cases, greatly tonifying the Spleen and Stomach is advisable.

Nongke Chuang (Pus-Nest Sore) is sized like a soybean, forming yellow purulent blisters with severe pain. Initially, itching occurs at the water blister stage, which then transforms into purulent blisters. This is formed by the interaction of Heat in the Lung Channel and Dampness in the Spleen Channel. Treatment should Clear Heat, disperse Wind, cool Blood, and remove Dampness, such as using Simiao Tang (Four Marvels Decoction) added with Fangfeng (Saposhnikoviae Radix) and Jingjie (Schizonepetae Spica), or Liangxiao Xiaofeng San (Cool Blood and Eliminate Wind Powder). Topically apply Pujidan (Universal Benefit Elixir), Shechuangzi San (Cnidus Seed Powder), or Yisaoguang (One Sweep Light). If painful rather than itchy, mix Erliang of raw Dahuang (Rhei Radix et Rhizoma) and one liang of raw Shigao (Gypsum Fibrosum), grind into powder, and apply mixed with sesame oil, while observing dietary restrictions; it will heal spontaneously.

Huangshui Chuang (Yellow Water Sore) suddenly presents as yellow blisters on the head, face, ears, and neck. Upon rupture, serous fluid flows out, spreading rapidly within moments, accompanied by pain and itching. This is due to sun exposure and wind blowing, causing Heat-Toxin to stagnate in the skin and hair, combined with sudden contraction of Damp-Heat. Alternatively, consuming Damp-Heat generating foods internally causes Wind to move and Fire to arise, triggering the eruption. Internal administration of herbs that dispel Wind, cool Blood, and Clear Heat is required. Externally, wash with decoction and apply Ge Fen San (Clam Shell Powder). Another method involves soaking one male pig gallbladder with one liang of Huangbai (Phellodendri Cortex), drying it by roasting, grinding into powder, and sprinkling it. Alternatively, mixing well-water (Jinghua Shui) for topical application yields excellent results.