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The pathogenic toxic qi diffuses and gathers in the Three Yang meridians, causing swelling; thus, Jiedu Tang (Decoction for Resolving Toxicity) is indicated, composed of Qianghuo (Notopterygii Rhizoma et Radix), Fangfeng (Saposhnikoviae Radix), Jingjie (Schizonepetae Herba), Niu Bang Zi (Arctii Fructus), Huang Qin (Scutellariae Radix), Lian Qiao (Forsythiae Fructus), Chai Hu (Bupleuri Radix), Jie Geng (Platycodonis Radix), and Shigao (Gypsum Fibrosum), each two qian. If the eruption has not yet fully emerged, remove Shigao.

Swelling of the nose indicates exhaustion of Lung Qi. Mouth gaping indicates exhaustion of Spleen Qi. Panting with chest oppression indicates extreme excess of Lung Fire that is difficult to descend, a condition that is incurable. Administer Qingfei Yin (Decoction for Clearing the Lungs) with heavy doses of Shigao and Huang Qin exceeding one liang; this may offer a slim chance of recovery, but medication should only be used if there is no severe reaction in the chest or at the tip of the nose.

Elevated breathing with audible panting, heaving chest and abdomen, indicates residual toxicity lodged in the Lung organ. Thick and sticky phlegm-saliva, grinding teeth, incessant diarrhea, and foul breath indicate residual toxicity lodged in the Stomach and Spleen. Night sweats, persistent fever, and intense thirst indicate residual toxicity lodged in the Heart meridian. Frequent fright in dreams, hand twitching and trembling, and red eyes indicate residual toxicity lodged in the Liver and Gallbladder. Heat in the ears and the tips of the hands and feet indicates residual toxicity lodged in the Kidney organ. Generalized edema that does not subside, high fever that does not recede, and depression/unrelieved discomfort indicate that residual toxicity remains unexhausted in all meridians.

When Heart Fire is extremely hyperactive, it scorches Lung Metal from above, causing obstruction of orifices, leading to incessant chills. Sweating methods are appropriate to release exterior heat. If constipation occurs, purgation is indicated; if urinary retention occurs, diuresis is indicated. The nature of Fire is fierce; it prefers dispersion over stagnation. Violating its nature, when it desires to disperse but cannot, Qi and Blood clash violently with Fire-Toxin within the interior, inevitably causing bodily shivering. Fire stagnation indeed causes shivering; sometimes excessive stagnation mimics cold symptoms, which is "extreme heat manifesting as water transformation," similar to how a person addicted to strong liquor might feel overwhelmed by cold. Only by using Mahuang (Ephedrae Herba) first can the toxic fire be loosened and penetrated, allowing the fiery nature to flow smoothly, thereby stopping the chills naturally.

When Fire Qi is scorching and oppressive, Lung Metal is constrained, and the source of Kidney Water generation is cut off. Thus, shortness of breath, fatigue, and sweating are symptoms of this meridian. Maidong Qingfei Yin (Ophiopogon Decoction for Clearing the Lungs) is indicated to moisten the dryness of Lung Metal.

Purple-red blisters arising during the suppuration stage transmitting to the Liver, with unresolved exterior and interior pathogens, causing boiling blood, are treated with Huanglian Jiedu Tang (Coptis Decoction for Resolving Toxicity) plus Xijiao (Rhinocerotis Cornu), Zicao (Lithospermi Radix), Sheng Di Huang (Rehmanniae Radix), Mu Dan Pi (Moutan Cortex), Shan Zhi (Gardeniae Fructus), and Mutong (Akebiae Caulis). White blisters indicate excess Qi and deficient Blood. Suppuration transmitting to the Lung, with heat-toxin lodging in the skin, causes body fluids to form blisters along with Qi. White and empty blisters indicate Qi deficiency; white blisters containing clear fluid indicate Qi excess. Treatment involves Chuan Lian (Coptidis Rhizoma), Shigao, Mu Dan Pi, Huang Qin, Sheng Di Huang, Jiang Can (Bombyx Batryticatus), Lian Qiao, and Xuan Shen (Scrophulariae Radix). Another view states: White blisters are also due to heat. The Classics say: "Blood heat causes macules; Qi heat causes blisters." It is also said: This is due to damp skin and abundant Kidney Water; ultimately, heat-toxin has not exited, and heat-pathogen harms the body first. Discussion holds: Excess Qi causes blisters; excess Qi means abundant toxic qi. At sites of conflict, the toxic edge shoots toward the chest; the "edge" refers to the blister sac developing with the toxic qi, hence the origin of blisters. When Qi and Blood are extremely locked, the color is white and the sac is empty. When Qi floats restlessly, it contains clear fluid; when Blood floats restlessly, the fluid resembles pickled fish. All are caused by toxic qi. Another saying goes: "Blood heat causes dryness; Blood cooling promotes growth," which is indeed true.