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A pregnant woman presented with generalized edema. Some considered it to be Baihuo Dan (White Fire Jaundice, a type of jaundice characterized by pale skin and edema), while others diagnosed it as Guzhang (Drum Distension, abdominal distension resembling a drum). All treatments were ineffective. The obstetrician Gu Dasheng stated: This is named Liuli Tai (Glue-like Fetus). One month before delivery, the patient will inevitably experience a significant increase in appetite, and the edema will resolve after childbirth. This indeed proved to be the case; he likely possessed extensive clinical experience. However, the etiology of this disease remained unknown.

Another woman at seven months of pregnancy first developed edema in the lower limbs, which gradually spread to her face and eyes. After several days, a blister suddenly protruded from the vagina, thin-skinned and shiny, causing the body's edema to completely subside. However, she experienced great difficulty and suffering in lying down or getting up. Later, the blister ruptured and discharged fluid, leaving the area constantly damp. An occasional relative claimed to have suffered from this condition previously; a physician had instructed her to wash with a decoction of *Viola yedoensis* Herba (Wangbuliuxing) and Alum (Mingfan), resulting in recovery. She tried this method as instructed but suffered from stinging pain. After more than a month, she improved slightly compared to before, but the condition was not completely cured. Obstetricians rarely knew of this condition, stating only that it seemed harmless and must be the so-called Liuli Tai, which would naturally disappear during delivery. This indeed proved to be the case. (Note: This condition may likely be Qi deficiency complicated by water retention.)

Another pregnant woman presented with generalized edema, which did not subside after delivery. She lay facing inward on the bed all day, in a state of coma and unconsciousness. Occasionally regaining slight consciousness, she became manic and restless. For over twenty days, she refused all food, and physicians were at a loss. A village old woman heard of this and told her: Do not worry. My daughter-in-law once had this condition too; she did not starve to death. Simply take aged dried salted fish (Chennian Baixiang), heat it near the patient, and pour rice vinegar over it. The aroma will naturally stimulate her appetite to eat. Following this advice, she recovered, and the edema subsided.

Xue Lizhai treated a pregnant woman who, at five months of each pregnancy, suffered from limb fatigue and loss of taste in food. Edema began in both legs, gradually spreading to the whole body, and then to the head and face. This was diagnosed as Spleen and Lung Qi Deficiency. He prescribed Buzhong Yiqi Tang (Tonify the Middle and Augment the Qi Decoction) in the morning and Liu Jun Zi Tang (Six Gentlemen Decoction) with Perillae Caulis (Sugeng) in the evening, resulting in recovery.

During the Yuanfeng era, Chen Jingchu from Huainan, a renowned physician, specifically wrote treatises and formulas for treating Zizhong (Submersion Swelling/Edema in Pregnancy) in pregnant women. His formula was initially called Xiangfu San (Cyperi Rhizoma Powder), later renamed Tianxianteng San (Tianxianteng Vinegar Powder) by Li Boshi. When Wang Jinggong (Wang Anshi) resided in Jinling and his entire family fell ill, he sent a poem to Jingchu: "The whole clan is poor and sick, troubling you with your medicinal efficacy. What do I have upon returning home? I ask the migrating geese for everything." Thus, the formula was obtained from Li Boshi's residence and transcribed at the residence of Vice Minister Zhang in Linchuan.

Xue Lizhai treated another woman with Zizhong using Zisu Yin (Perilla Infusion), resulting in recovery after three doses.