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Patients with gallbladder disease often sigh deeply, experience bitter taste in the mouth, vomit old bile fluid, feel palpitations and fear as if being pursued by someone, have a sensation of obstruction in the throat (Yan), and frequently spit saliva. The diagnostic signs are located at the root and extremity (Benmo) of the Foot-Shaoyang channel; if the pulse is sunken or depressed, moxibustion should be applied. For symptoms of chills and fever, needle the Yanglingquan (GB34) acupoint. If there is frequent vomiting of bitter fluid, long sighing, palpitations in the heart, excessive sadness and fear, feeling as if being hunted, this indicates pathogenic factors in the Gallbladder and rebellious Qi in the Stomach. The leakage of gall juice causes bitter taste, while rebellious Stomach Qi causes vomiting of bitter fluid; hence it is called "vomiting from the Gallbladder" (Ou Dan). Needle the Zusanli (ST36) acupoint to descend rebellious Stomach Qi; needle the blood collaterals of the Foot-Shaoyang channel to close off the Gallbladder pathogen; then regulate deficiency and excess to eliminate the pathogen.

Gallbladder distension presents with pain and fullness under the hypochondrium, bitter taste in the mouth, and frequent sighing.

When Jue Qi (rebellious cold/yin qi) lodges in the Gallbladder, one dreams of fighting and litigation.

The Foot-Shaoyang Gallbladder Meridian originates at the outer canthus of the eye, ascends to the head corner, descends behind the ear, follows the neck, runs anterior to the Hand-Shaoyang Sanjiao Meridian, reaches the shoulder, crosses posterior to the Hand-Shaoyang, and enters the supraclavicular fossa (Quepen). A branch enters the ear from behind the ear, emerges anterior to the ear, and reaches the post-auricular region. Another branch diverges from the outer canthus, descends to Daying (LI17), and joins the Hand-Shaoyang at the infraorbital region (alternative text: diverges from the outer canthus, ascends to the vertex to join the Hand-Shaoyang), descends to Jiache (ST6), goes down the neck, joins the Quepen, descends into the chest, penetrates the diaphragm, connects with the Liver, and belongs to the Gallbladder. It follows the interior of the hypochondrium, emerges at the Qichong (ST30) area, surrounds the pubic hair margin, and transversely enters the hip joint (Biyan). The straight course descends from the Quepen to the axilla, follows the chest, passes through the costal margin, joins the hip joint below, descends along the lateral aspect of the thigh, emerges at the lateral knee, runs anterior to the fibula, reaches the end of the Juegu (lower fibula), emerges anterior to the lateral malleolus, follows the dorsum of the foot, and exits at the tip of the fourth toe. A branch on the dorsum of the foot enters between the big toe, follows the medial side of the big toe's bifurcation, exits the tip, returns to penetrate the nail bed, and emerges at the trichiasis area (Sanmao). When this meridian is disturbed, diseases include bitter taste, frequent sighing, pain in the heart and hypochondrium, inability to turn the body, severe cases showing a dusty complexion, lack of luster in the body, and heat on the lateral aspect of the foot; this is termed Yang Jue (Yang Rebellion). This meridian governs diseases arising from the bones, including headache, pain at the temple and jaw, pain at the outer canthus, swelling and pain in the Quepen, axillary swelling, scrofula (Madao and Xiaying), sweating, chills, malaria, pain in the chest, hypochondrium, thigh, lateral knee to the popliteal fossa, Juegu, and anterior to the lateral malleolus, and pain in all joints, with dysfunction of the fourth toe. In cases of excess, the Renying pulse is twice as large as the Cun Kou pulse; in cases of deficiency, the Renying pulse is smaller than the Cun Kou pulse.