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Yin and Yang qi, specifically the clear and turbid aspects, interfere with each other, termed "Qi Disarray" (Qì Luàn). When Qi Disarray occurs in the intestines and stomach, it manifests as Cholera-like disorder (Huò Luàn). This is often caused by excessive eating or drinking, and exposure to wind-cold pathogens. Cold qi enters the abdomen; when spleen qi is affected by cold, it fails to transform water and grain; when stomach qi is affected by cold, vomiting and regurgitation occur; when intestinal qi is affected by cold, diarrhea ensues. If heart pain appears first, vomiting occurs first; if abdominal pain appears first, diarrhea occurs first; if both heart and abdomen hurt, vomiting and diarrhea occur simultaneously. Cases presenting with headache, high fever, vomiting, and diarrhea arise because a robust constitution combined with pathogenic wind qi struggles on the exterior against blood and qi, causing headache and fever; internally, this pathogen invades the intestines and stomach, causing the vomiting and diarrhea of Cholera-like disorder.

Rebellious Stomach Qi (Wèi Qì Nì) leads to vomiting. The Stomach (Wèi) is the Sea of Water and Grain; if its qi is disordered and wind-cold pathogens invade, the cold combats the Stomach Qi, causing it to rebel upward, resulting in vomiting.

Regardless of gender, feeling mental oppression, confusion, headache, and vomiting while riding in carriages or boats is termed "Zhuche" (Note Carriage) or "Zhuchuan" (Note Boat). This is specifically due to one's natural constitution, not related to past-life karma. Humans are born from the refined qi of the Five Elements and nourished by the spiritual qi of the Five Zang Organs. If Yin and Yang are harmonious, the Zang-Fu organs become strong, and wind pathogens or ghosts cannot harm them. However, if self-care and protection are neglected, leading to deficiency and decline of blood and qi, wind pathogens will take advantage of the deficiency, and ghostly influences will attack the upright qi. In women who suffer from intercourse with ghosts, it is because the Zang-Fu organs are deficient and the Spirit (Shen) lacks retention power, allowing ghost qi to cause disease. The symptoms include: aversion to seeing people, as if facing an adversary, talking and laughing alone, or occasionally weeping bitterly.

A pulse that is slow and deep (Chi Fu), or intermittent like a bird pecking, indicates disease caused by evil entities. Also, a pulse that is continuous and fine without discernible rate, yet the complexion remains unchanged, is also a sign of disease.

Deficiency of the Zang organs predisposes one to dreams. Women dreaming of intercourse with ghosts also result from weak organ qi and deficient Shen retention, allowing ghost interaction through dreams due to deficiency.

Hongxiangjiao (Foot Qi Disease) arises from human deficiency, where warm-dampness and wind-toxic qi first lodge in the feet, ascending from below and disturbing the Qi mechanism, hence the name Hongxiangjiao. In the Jiangdong and Lingnan regions, the land is low and damp, making people susceptible to wind-dampness. Initially, this disease is often unnoticed; one may have no prior illness and suddenly contract it, or acquire it after other illnesses. The disease starts subtly; diet, play, and strength remain normal, so careful observation is required. Symptoms include: numbness from knees to feet, sensation similar to Bi syndrome, itching like insects crawling, slight swelling, extreme cold, pain, flaccidity and inability to move, or tendon cramping; some are lethargic but can eat, some cannot eat, some vomit at the sight of food or detest food odors; some have lipid-like substances originating in the intestines, rushing upward to strike the heart with rebellious Qi; some experience generalized tendon spasms; some have high fever and headache; some have chest palpitations and dislike light during rest; some have severe abdominal pain accompanied by diarrhea; some speak confusedly and are forgetful; some have cloudy eyes and dull spirit. These are all its manifestations. If treatment is delayed, the pathogen ascends into the abdomen, potentially causing abdominal swelling, chest and hypochondriac fullness, and death from rebellious Qi. Acute cases may lead to death within a day; slower cases within two or three days.

Once the pathogen enters the Zang organs, the clinical presentations are similar, but there are three types of pulses: If the pulse is floating, large, and slow, Xuming Tang (Cure-all Decoction) should be administered for two doses; if Wind is predominant, Yebip Tang (Yi Ma Decoction) with four liang of Atractylodis Macrocephalae Rhizoma (Baizhu) should be prepared. If the pulse becomes rapid and tight, Zhuli Tang (Bamboo Juice Decoction) is suitable; if the pulse is faint, Fengyin Tang (Wind-Quelling Decoction) should be taken for two to three doses. The tight and rapid pulse is the most ominous among these three. A floating-large pulse indicates the disease is external; a deep-fine pulse indicates the disease is internal. Both require urgent treatment. Delayed treatment leads to rebellious Qi and death.