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Shi Qi Bing (Seasonal Febrile Disease) is characterized by a deficiency of Yin Qi (Yin Energy) and an excess of Yang Qi (Yang Energy), resulting in feverish body sensation and mental restlessness. If the toxic heat resides in the Heart causing restlessness, it leads to chest oppression and nausea; if the restlessness is caused by dry feces retained in the Stomach, it results in delirious speech, periumbilical pain, and abdominal fullness. All these conditions require careful observation of their clinical manifestations.

When the disease is severe, patients may discard their clothes and run, climb high places and sing, or go without food for several days, jumping over walls and climbing onto roofs. These actions exceed their normal capabilities. The ability to perform such feats arises from the contention between Yin and Yang, where pathogenic factors merge outwardly with Yang. The four limbs are the root of all Yang meridians. When pathogenic factors are excessive, the four limbs become robust, enabling one to climb and sing; when heat is excessive in the body, one discards clothes and runs; when Yang is excessive, one speaks wildly and curses without regard for kinship. Generalized high fever leads to delirious speech and hallucinations (visual and auditory).

Heat in the Stomach combines with the Qi of food entering the stomach, causing rebellious Qi and vomiting. Alternatively, after sweating or purging, excessive water intake may lead to a cold and deficient Stomach, also resulting in vomiting.

Heat accumulating in the Spleen and Stomach, or remaining after sweating or severe purging, causes disharmony in the Stomach with residual heat. This rising heat steams upward, causing mental restlessness.

Latent heat in the Stomach causes chest fullness. Chest fullness leads to rebellious Qi, which in turn causes hiccups (Yue). After severe purging, a cold and deficient Stomach Qi can also cause hiccups.

When pathogenic heat invades the Lung, upper Jiao (Triple Burner) heat occurs. The patient desires water, but if water stagnates below the heart (epigastrium), it ascends to the Lung, causing rebellious Qi and coughing.

When heat enters the Kidney, since the Kidney dislikes dryness, excessive heat causes Kidney dryness, leading to thirst and the desire to drink.

Epistaxis (Nosebleed) in Shi Qi Bing is caused by heat accumulation in the five Zang organs. The Heart governs blood. Pathogenic heat invades the Hand Shaoyin (Heart) meridian and lodges in the collaterals of the Foot Yangming (Stomach) meridian, causing epistaxis. "Nu" refers to bleeding from the nose.

If diseases affecting all Yang meridians are not treated with sweating to release the exterior, deep-seated heat toxins bind within the five Zang organs, forming blood stasis, leading to hematemesis (vomiting blood).

After sweating and purging, both the exterior and interior are deficient. If toxic vapors remain unexhausted and steam the upper Jiao, sores may form in the throat and mouth.

When Yin and Yang are severed, pathogens lodge in the collaterals of the Foot Shaoyin (Kidney) meridian. Toxic vapors steam upward and attack the throat region, causing sore throat or ulceration.