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Treats Taiyang disease (disease of the Taiyang channel) where excessive sweating has led to continuous leakage of sweat, with the patient experiencing aversion to wind, difficulty in urination, stiffness and spasms of the four limbs making flexion and extension difficult; it also treats abdominal pain caused by Cold Cramp (Han Shan), accompanied by cold hands and feet, body pain, and numbness.
The original Guizhi Tang (Cinnamon Twig Decoction) plus one fried Fuzi (Prepared Aconite Lateral Root).

Guizhi Jia Fuzi Tang (Cinnamon Twig Decoction with Added Prepared Aconite) urgently warms the meridians, stops sweating, restores Yang Qi, and thereby rescues Body Fluids. (This treats the condition where Yang Qi is lost externally while Yin Fluids are depleted internally. Although Shu Fuzi (Prepared Aconite) can tonify Yang, its nature is ultimately drying and damaging to fluids. Zhang Zhongjing considered that Guizhi Tang has a light and mild action, so it must rely on the potent nature of Fuzi to penetrate both interior and exterior, urgently warming the meridians and restoring Yang Qi, preventing further sweat loss, which is precisely how it preserves fluids.) If sweat continues to leak and aversion to wind persists (indicating residual pathogenic factors at the exterior), difficulty in urination (due to fluid depletion), and limb stiffness (due to Yang deficiency and fluid loss leading to poor joint mobility) occur, recovery is possible. ("Continuous leaking sweat" is similar to "profuse sweating"; if there are no other complicated symptoms, Guizhi Tang should still be used. If symptoms resemble malaria [alternating chills and fever], it indicates that the Xuanfu [pores] are closed, hence Mahuang (Ephedra) is added. Here, since the Xuanfu are not closed, Fuzi is added. If after profuse sweating there is severe restlessness and thirst, it indicates Yang Qi sinking into the interior, requiring urgent nourishment of Yin, thus Baihu Jia Renshen Tang (White Tiger Decoction with Added Ginseng) is used. Here, with continuous leaking sweat, difficulty in urination, and limb stiffness, it indicates Yang Qi perishing at the exterior, requiring urgent support of Yang, thus Guizhi Jia Fuzi Tang is used. Such is the accuracy of diagnosis and precision of medication by Zhang Zhongjing.)

Treats Huanghan (Yellow Sweat) with fever, spontaneous coldness in both calves, heaviness and pain in the body, sweating accompanied by thirst, sweat only above the waist with none below, sweat staining clothes bright yellow like cypress juice, flaccid pain in the waist as if something were trapped under the skin, severe cases unable to eat, heavy body with irritability, and difficulty in urination; this formula is indicated. It also treats various cases of Jaundice (Huang Bing) where the pulse is floating.
The original Guizhi Tang plus three taels of Huangqin (Scutellaria Root).

Guizhi Jia Huangqin Tang (Cinnamon Twig Decoction with Added Scutellaria) treats Huanghan (because the sweat is yellow, the disease is named accordingly). The body feels hot while the calves are cold, accompanied by mental restlessness. (Dampness injuring the lower part causes cold calves. Dampness rising and becoming heat causes body heat and mental restlessness.) Flaccid pain in the waist (due to lack of sweat below the waist) and difficulty in urination (due to chaotic mixing of damp-heat and failure of Qi mechanism transformation). Sweating occurs only from the upper half of the waist. Harmonizing Ying and Wei (Nutritive and Defensive levels) to dispel pathogens, allowing dampness stagnating in the skin to dissipate through sweat. (This formula treats dampness stagnating in the skin with internal stagnation of Yang Qi and insecure exterior defense. Thus, Huangqin is used to secure the exterior, and Guizhi Tang promotes Yang Qi and harmonizes Ying and Wei, allowing the yellow sweat to resolve through sweating.) In cases of various jaundices with a floating pulse, this formula may also be consulted for assistance. (A floating pulse indicates the pathogen is at the exterior, requiring resolution through sweating. If the pulse is deep, promoting diuresis is required instead.) Yellow sweat staining clothes bright yellow indicates the cause is determined to be damp-heat. Li Jie Feng Shi (Bi Syndrome resembling joint pain due to wind-damp) and Feng Shui (Wind Water edema) are quite similar to this; upon clinical investigation, the principles can be distinguished. (Huanghan resembles Li Jie, but Li Jie involves heat throughout the whole body, whereas Huanghan presents with body heat and cold calves. It also resembles Feng Shui, but Feng Shui involves aversion to wind, while Huanghan does not. Furthermore, the sweat in Li Jie and Feng Shui is not yellow, which serves as a distinguishing feature.)