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Zhongbi (a type of Bi syndrome characterized by fixed pain sites that alternate in onset) each remains at its respective location. It alternates in onset and cessation; it alternates in resting and rising. Symptoms on the right correspond to those on the left, and symptoms on the left correspond to those on the right. It is not capable of circulating throughout the body. It alternates in onset and rest.
(Note: "Each remains at its respective location" means that pain arises where pathogenic factors gather. It cannot circulate extensively up and down the body, but rather occurs alternatively on the left or right, alternating in onset and rest, with no fixed site of affliction. Hence, it is called Zhongbi.)
To treat this, even if the pain has ceased, one must still needle the original site of pain to prevent recurrence. (This states that one must needle the site where the initial pain occurred.)

Zhoubi (a type of Bi syndrome that moves along the blood vessels and circulates throughout the body) resides within the blood vessels. It follows the meridians upward and downward but does not correspond separately to locations on the left and right like Zhongbi. (It can move up and down, circulating throughout the body via the blood vessels, hence it is called Zhoubi.)
When pain develops from above downward, first needle the lower part to obstruct the pathogenic progression, then needle the upper part to eradicate the root cause. When pain develops from below upward, first needle the upper part to obstruct the pathogenic progression, then needle the lower part to eradicate the root cause. ("Guo" refers to removing the pathogen, specifically addressing the branch/symptom first; "Tuo" refers to severing the root, specifically addressing the root cause later.)

This occurs because Wind, Cold, and Dampness pathogens invade the exterior and lodge between the fenrou (muscle intervals), pressing upon fluids to form foam. The foam aggregates when exposed to Cold; aggregation causes pressure on the fenrou, leading to separation. Separation results in pain. (Pathogens lodging in the muscle surface gradually enter the fenrou, pressing fluids into juice and foam. When the foam encounters Cold, it aggregates and does not dissipate, thereby pressing and splitting the muscle texture to cause pain.)
When there is pain, the Shen (Spirit/Mind) focuses on the affected area. When the Shen focuses on the area, heat is generated. When there is heat, the pain resolves temporarily. When the pain resolves, Jue (Qi reversal/stagnation) occurs. Jue leads to the manifestation of other Bi syndromes, which present in this manner. (When in pain, the heart-mind focuses on the site, so the Shen returns there. Shen returning implies Qi returning; thus, heat is generated. Heat disperses Cold, temporarily relieving pain. However, the Qi remains rebellious, causing Jue. Jue allows the three pathogens to follow the blood vessels up and down; pain may transmit from top to bottom or bottom to top. This Bi manifests within the blood vessels, unlike Zhongbi which shifts between left and right.)

This condition is internally not located in the Zang-Fu organs and externally has not yet manifested in the skin; it resides solely between the fenrou, preventing the True Qi from circulating freely throughout the body. (Referring to systemic pain syndromes.) Therefore, it is named Zhoubi. (Blockage of Qi circulation throughout the body.)
Therefore, when treating Bi syndrome, one must first palpate and guide the Six Meridians of the Foot. (Referring to the six foot meridians.) As well as the large collaterals where blood is knotted and obstructed. (Should be treated with draining methods.) And those that are deficient, with sunken and empty pulses. (Should be treated with tonifying methods.)
Use moxibustion/heat therapy (Wen) to unblock the meridians. (Suitable for cases where Cold coagulation prevents Qi circulation.) For cases of muscle twitching and tendon contraction/spasm. (Meaning acute twitching and tendon turning.) Guide the Qi through needling manipulation. (Using needles to guide the Qi to promote its circulation.)