六十五难曰∶经言所出为井，所入为合，其法奈何？然∶所出为井，井者，东方春也，万物之始
生，故言所出为井也。所入为合，合者、北方冬也，阳气入藏，故言所
入为合也。
六十六难曰∶“经言、肺之原，出于太渊；心之原，出于大陵；肝之原，出于太冲；脾之原，出于
太白；肾之原，出于太溪；少阴之原，出于兑骨；胆之原，出于丘墟；胃之原，出于冲阳；三焦之原，
出于阳池；膀胱之原，出于京骨；大肠之原，出于合谷；小肠之原，出于腕骨。十二经皆以俞为原者，何也？
然∶五脏俞者，三焦之所行，气之所留止也。三焦所行之俞为原者，何也？然∶脐下肾间动气
者，人之生命也，十二经之根本也，故名曰原。三焦者，原气之别使也，主通行三气，经历于五脏六
腑。原者、三焦之尊号也，故所止辄为原。五脏六腑之有病者，皆取其原也。
六十七难曰∶五脏募皆在阴，而俞在阳者，何谓也？然∶阴病行阳，阳病行阴，故令募在阴，俞在阳。
六十八难曰∶五脏六腑，皆有井荥俞经合，皆何所主？然∶经言所出为井，所流为荥，所
注为俞，所行为经，所入为合。井、主心下满，荥、主身热，俞、主体重节痛，经、主喘咳寒热，
合、主逆气而泄，此五脏六腑井荥俞经合所主病也。
第六十五难说：经书中说“所出为井，所入为合”，其原理是怎样的呢？回答说：所谓“所出为井”，井者，对应东方春季，是万物开始生长的时节，所以说“所出为井”。所谓“所入为合”，合者，对应北方冬季，阳气潜藏入于体内，所以说“所入为合”。
第六十六难说：“经书指出，肺的原穴出于太渊；心的原穴出于大陵；肝的原穴出于太冲；脾的原穴出于太白；肾的原穴出于太溪；心包络（手厥阴心包经）的原穴出于兑骨（即大陵）；胆的原穴出于丘墟；胃的原穴出于冲阳；三焦的原穴出于阳池；膀胱的原穴出于京骨；大肠的原穴出于合谷；小肠的原穴出于腕骨。为什么十二经脉都以俞穴作为原穴呢？”回答说：五脏的俞穴，是三焦之气运行的通道，也是元气停留和汇聚的地方。为什么三焦运行的俞穴就是原穴呢？回答说：脐下肾间动气，是人的生命根本，也是十二经脉的根本，所以称为“原”。三焦是原气的别使（分支使者），主要通行上、中、下三焦之气，流经五脏六腑。原穴是三焦尊贵的称号，所以元气停留之处就称为原穴。五脏六腑如果有疾病，都可以取用原穴进行治疗。
第六十七难说：五脏的募穴都在阴面（胸腹部），而俞穴都在阳面（背部），这是什么意思呢？回答说：阴病会反映到阳面，阳病会反映到阴面，所以令募穴在阴面，俞穴在阳面。
第六十八难说：五脏六腑都有井、荥、俞、经、合五输穴，它们各自主治什么病症呢？回答说：经书说“所出为井，所流为荥，所注为俞，所行为经，所入为合”。井穴主治心下满闷，荥穴主治身体发热，俞穴主治身体沉重和关节疼痛，经穴主治气喘咳嗽和寒热往来，合穴主治气逆和泄泻。这就是五脏六腑井、荥、俞、经、合五输穴各自主治的病症。
Difficulty 65 states: The Classics say, "The point where Qi emerges is the Jing-Well (Jing), and the point where Qi enters is the He-Sea (He)." What is the rationale behind this? The answer is: "The point where Qi emerges is the Jing-Well. 'Jing' corresponds to the East and Spring, which is the time when all things begin to grow; therefore, it is said that 'the point where Qi emerges is the Jing-Well.' The point where Qi enters is the He-Sea. 'He' corresponds to the North and Winter, when Yang Qi enters and stores within the interior; therefore, it is said that 'the point where Qi enters is the He-Sea.'"
Difficulty 66 states: "The Classics state: The Yuan-Source (Yuan) of the Lung meridian emerges from Taiyuan (LU-9); the Yuan-Source of the Heart meridian emerges from Daling (PC-7); the Yuan-Source of the Liver meridian emerges from Taichong (LR-3); the Yuan-Source of the Spleen meridian emerges from Taibai (SP-3); the Yuan-Source of the Kidney meridian emerges from Taixi (KI-3); the Yuan-Source of the Pericardium meridian (Shao Yin of Hand) emerges from Duigu (which is Daling, PC-7); the Yuan-Source of the Gallbladder meridian emerges from Qiuxu (GB-40); the Yuan-Source of the Stomach meridian emerges from Chongyang (ST-42); the Yuan-Source of the Sanjiao (Triple Burner) meridian emerges from Yangchi (TE-4); the Yuan-Source of the Bladder meridian emerges from Jinggu (BL-64); the Yuan-Source of the Large Intestine meridian emerges from Hegu (LI-4); the Yuan-Source of the Small Intestine meridian emerges from Wangu (SI-4). Why do all twelve meridians use the Shu-Stream (Shu) points as their Yuan-Source points?" The answer is: The Shu-Stream points of the five Zang organs are the pathways through which Qi of the Sanjiao travels, and they are places where Qi stays and stops. Why are the Shu-Stream points traveled by the Sanjiao considered the Yuan-Source points? The answer is: The moving Qi between the kidneys below the navel is the root of human life and the foundation of the twelve meridians; hence it is named "Yuan" (Original). The Sanjiao is the special envoy of the Original Qi, primarily responsible for circulating the Qi of the Upper, Middle, and Lower Jiao, passing through the five Zang and six Fu organs. "Yuan" is the honorific title of the Sanjiao; therefore, wherever the Qi stops, it is called a Yuan-Source point. When any of the five Zang or six Fu organs have disease, one should select their Yuan-Source points."
Difficulty 67 states: "The Mu-Alarm (Mu) points of the five Zang organs are all located on the Yin aspect (anterior trunk), while the Shu-Back (Shu) points are on the Yang aspect (posterior trunk). What does this mean?" The answer is: Yin diseases manifest on the Yang aspect, and Yang diseases manifest on the Yin aspect; thus, the Mu points are located on the Yin aspect, and the Shu points are located on the Yang aspect."
Difficulty 68 states: "The five Zang and six Fu organs each have the Five Shu points: Jing-Well, Ying-Spring, Shu-Stream, Jing-River, and He-Sea. What symptoms does each category primarily treat?" The answer is: The Classics state, 'What emerges is the Jing-Well, what flows is the Ying-Spring, what pours into is the Shu-Stream, what moves along is the Jing-River, and what enters is the He-Sea.' The Jing-Well points primarily treat fullness in the epigastrium/heart region; the Ying-Spring points primarily treat feverish sensations in the body; the Shu-Stream points primarily treat heaviness of the body and pain in the joints; the Jing-River points primarily treat wheezing, coughing, and alternating chills and fever; the He-Sea points primarily treat rebellious Qi and diarrhea. These are the primary indications for the Jing-Well, Ying-Spring, Shu-Stream, Jing-River, and He-Sea points of the five Zang and six Fu organs."