治疟症二、三发后，以此止之，应手取效。
常山（火酒炒） 草果仁（去壳） 半夏曲（姜汁炒） 香附米（酒炒） 青皮（去穣醋炒，各四
两） 真六神曲（十二两
为末，用米饮煮糊为丸，如弹子大，朱砂为衣。轻者一丸，重者二丸，红枣五、六枚，
煎汤化下，清晨面东空腹服。
六君子汤、补中益气汤 （俱见类中。
疟久变虚，宜用前二方主之，但真虚者多挟寒，须用肉桂、附子、炮姜、砂仁之类，温
问曰∶水肿、鼓胀，何以别之？答曰∶目窠与足先肿，后腹大者，水也；先腹大，后四
肢肿者，胀也。然水肿亦有兼胀者，胀亦有兼水者，须按其先后多寡而治之，今分为两门，
水肿症，有表里、寒热、肾胃之分，大抵四肢肿，腹不肿者，表也。四肢肿，腹亦肿
者，里也。烦渴口燥，溺赤便闭，饮食喜凉，此属阳明，热也。不烦渴，大便自调，饮食喜
热，此属阴水，寒也。先喘而后肿者，肾经聚水也。先肿而后喘，或但肿而不喘者，胃经蓄
水也。经云∶肾者，胃之关也。关闭则水积，然胃病而关亦自闭矣。治胃者，五加皮饮加减主
之。治肾者，肾气丸加减主之。或问∶书云∶先喘后肿，其病在肺，何也？答曰∶喘虽肺病
其本在肾，经云∶诸痿喘呕，皆属于下是也。若外感致喘，或专属肺经受邪，内伤致喘，
未有不由于肾者，治者详之。
治疗疟疾发作两三次后，用此方来制止，往往能立即见效。
常山（用黄酒炒制） 草果仁（去掉外壳） 半夏曲（用姜汁炒制） 香附米（用酒炒制） 青皮（去掉白色内瓤，用醋炒制，以上五味药各四两） 真六神曲（十二两）
将上述药物研成细末，用米汤煮成糊状制成丸药，大小如弹子，外用朱砂粉末包裹衣层。病情轻者服用一丸，病情重者服用两丸，配合红枣五到六枚，煎汤送服丸药，清晨面向东方空腹服用。
六君子汤、补中益气汤 （均见于中风类章节）。
疟疾日久导致身体虚弱，适宜使用前两个方剂主治，但真正的虚证多夹杂寒邪，必须使用肉桂、附子、炮姜、砂仁这类药物，进行温补。
问：水肿和鼓胀，如何区分？答：眼睑和足部先出现肿胀，随后腹部胀大的，是水肿；先腹部胀大，随后四肢肿胀的，是鼓胀。然而水肿也有兼夹胀满的情况，鼓胀也有兼夹水湿的情况，必须根据发病的先后顺序和病情的轻重主次来治疗，现在将其分为两个门类。
水肿症，有表里、寒热、肾胃之分。大致来说，四肢肿胀而腹部不肿的，属于表证。四肢肿胀，腹部也肿胀的，属于里证。心烦口渴，口舌干燥，小便赤红，大便闭塞，饮食喜凉，这属于阳明经，是热证。不心烦口渴，大便正常，饮食喜热，这属于阴水，是寒证。先气喘而后出现肿胀的，是肾经积聚水湿。先肿胀而后气喘，或者只肿胀而不气喘的，是胃经蓄积水湿。经典记载说：“肾，是胃的关口。”如果关口关闭，则水液积聚，然而胃病也会导致关口自行关闭。治疗胃病引起的，以五加皮饮加减为主方。治疗肾病引起的，以肾气丸加减为主方。有人问：书上说“先喘后肿，病在肺”，这是为什么呢？回答是：气喘虽然与肺有关，但其根本在于肾，经典记载说：“各种痿证、气喘、呕吐，都归属于下焦（肾）。”如果是外感导致的气喘，或许专门属于肺经受邪；如果是内伤导致的气喘，没有不是由于肾引起的，治疗者需仔细辨别。
After the malaria syndrome has manifested two or three times, this formula can be used to arrest it, often yielding immediate results.
*Changshan* (Fire-wine fried) [Dichroae Radix] *Caoguoren* (Shelled) [Tsaoko Fructus] *Banxiaqu* (Ginger-juice fried) [Pinelliae Rhizoma Praeparatum] *Xiangfum* (Wine-fried) [Cyperi Rhizoma] *Qingpi* (Albedo removed, Vinegar-fried), each four taels; *Zhen Liushenqu* (True Six-God Qu) twelve taels.
Grind into powder, use rice drink to boil and make paste for pills, size of a bullet, coated with *Zhusha* (Cinnabar). For mild cases, one pill; for severe cases, two pills. Take with decoction of five or six red dates, swallowed in the morning on an empty stomach, facing east.
*Liu Junzi Tang* (Six Gentlemen Decoction), *Buzhong Yiqi Tang* (Tonify the Middle and Augment the Qi Decoction) (Both seen under the category of Stroke).
When malaria persists and transforms into deficiency, the aforementioned two formulas should be primarily used. However, true deficiency cases often involve cold pathogens, requiring the addition of herbs such as *Rougui* (Cinnamon Bark), *Fuzi* (Prepared Aconite Root), *Paojiang* (Baked Ginger), and *Sharen* (Amomum Fruit) to warm and tonify.
Question: How to differentiate between edema (*Shuizhong*) and distension/tympanites (*Guzhang*)? Answer: If swelling starts in the eye sockets and feet, followed by abdominal enlargement, it is water retention (edema); if abdominal enlargement occurs first, followed by swelling of the four limbs, it is distension (tympanites). However, edema may also present with accompanying distension, and distension may also present with accompanying water retention. Treatment must be determined based on the sequence of onset and the predominance of symptoms. Now, they are divided into two separate categories.
Edema syndromes are differentiated by exterior/interior, cold/heat, and Kidney/Stomach involvement. Generally, swelling of the four limbs without abdominal swelling indicates an exterior syndrome. Swelling of both the four limbs and the abdomen indicates an interior syndrome. Restlessness, thirst, dry mouth, dark urine, constipation, and preference for cool foods indicate involvement of the Yangming channel, representing a heat syndrome. Absence of restlessness and thirst, normal bowel movements, and preference for hot foods indicate Yin-water, representing a cold syndrome. Wheezing preceding swelling indicates water accumulation in the Kidney channel. Swelling preceding wheezing, or swelling without wheezing, indicates water retention in the Stomach channel. The Classics state: "The Kidney is the gate of the Stomach." When the gate closes, water accumulates; however, Stomach disease can also cause the gate to close autonomously. For treating Stomach-related issues, modify *Wujiapi Yin* (Acanthopanacis Cortex Drink). For treating Kidney-related issues, modify *Shenqi Wan* (Kidney Qi Pill). One might ask: Books state that "wheezing preceding swelling indicates lung pathology," why is this so? The answer is: Although wheezing involves the Lung, its root lies in the Kidney. The Classics state: "All flaccidity disorders, wheezing, and vomiting belong to the lower jiao." If wheezing is caused by external contraction, it may specifically relate to pathogenic invasion of the Lung channel; if caused by internal injury, it invariably stems from the Kidney. Practitioners should examine this carefully.