关尹子曰∶人之一身，内包蛲蛔，外蒸虮虱，万物有根据人身以为生者，是吾身一小天地
也
又能变生诸虫，不可名状，如发症、鳖瘕、劳瘵、传尸之类，至于杀身灭门。虫之为患，若
斯其酷也。是以先贤以法杀之，苟人不能杀虫，则虫必且杀人矣。
（仲景）
治伤寒厥阴证，寒厥吐蛔（伤寒脏厥者死。脏厥者，脉微而厥，至七八日肤冷发躁，无
暂安时也。蛔厥者，蛔上入膈则烦，须臾复止，得食则呕而又烦，蛔闻食臭复出也。此为脏
寒，当
乌梅（三百个） 细辛 桂枝 人参 附子（炮） 黄柏（六两） 黄连（一斤） 干
姜（十两） 川椒（去汗） 当归（四两。）苦酒（醋也）浸乌梅一宿，去核，蒸熟，和药
蜜丸。
此足阳明、厥阴药也。蛔得酸则伏，故以乌梅之酸伏之；蛔得苦则安，故以连柏之苦安
之；
兼以敛肺（吐蛔为胃寒之故，则成蛔厥，宜理中汤加炒川椒五粒、槟榔五分，吞乌梅丸。程
郊倩曰∶乌梅丸于辛酸入肝药中微加苦寒，纳上逆之阳邪而顺之使下也，名曰安蛔，实是安
胃，故并主久痢，见阴阳不相顺接而下利之证，皆可以此方括之也。经曰∶凡阴阳不相顺接，
便为厥。方中行曰∶经曰、手之三阴从腹走手，手之三阳从手走头，足之三阳从头走足，足
之三阴从足走腹，是三阴三阳俱相接于手足者也。阳气内陷，不与阴气相顺接，故手足逆冷
也）。
关尹子说：人的身体内部包含蛲虫和蛔虫，外部滋生虱子和虮子，万物都有依靠人身来生存的，这说明我们的身体就是一个小天地。
又能变化生出各种虫子，形状不可名状，如发症、鳖瘕、劳瘵、传尸之类的疾病，甚至导致杀身灭门。虫子带来的祸患，竟然如此残酷。因此先贤用方法来杀灭它们，如果人不能杀虫，那么虫子必定会杀人。
（张仲景）治疗伤寒厥阴证，寒厥吐蛔（伤寒脏厥者死。脏厥，是指脉象微弱且四肢厥冷，到了七八天皮肤发冷、烦躁不安，没有片刻安宁的时候。蛔厥，是蛔虫上入膈部则心烦，一会儿又停止，进食后呕吐并且心烦，因为蛔虫闻到食物的气味就出来活动。这是因为内脏寒冷，应当使用乌梅丸）。
乌梅（三百个）、细辛、桂枝、人参、附子（炮制）、黄柏（六两）、黄连（一斤）、干姜（十两）、川椒（去汗）、当归（四两）。用苦酒（即醋）浸泡乌梅一夜，去核，蒸熟，与药物混合制成蜜丸。
这是足阳明经、足厥阴经的药物。蛔虫遇到酸味就会伏藏，所以用乌梅的酸味来伏住它；蛔虫遇到苦味就会安定，所以用黄连、黄柏的苦味来安抚它；兼有收敛肺气的作用（吐蛔是因为胃寒的缘故，从而形成蛔厥，适宜用理中汤加炒川椒五粒、槟榔五分，吞服乌梅丸。程郊倩说：乌梅丸在辛酸入肝的药物中微微加入苦寒之品，接纳上逆的阳邪并引导其下行，名义上是安蛔，实际上是安胃，所以也主治久痢，见到阴阳不相顺接而导致的下利症状，都可以用这个方剂概括。经文说：凡是阴阳不相顺接，就会发生厥证。方中行说：经文说，手三阴经从腹部走向手部，手三阳经从手部走向头部，足三阳经从头部走向足部，足三阴经从足部走向腹部，这样三阴三阳都在手足处相接。阳气内陷，不与阴气相顺接，所以手足逆冷）。
Guan Yinzi said: Within the human body, there are pinworms and roundworms; on the exterior, lice and nits thrive. All things have their basis in the human body for survival, indicating that our body is a small universe.
It can also transform into various insects, indescribable in form, such as fa zheng (hair-like growth disease), bie jia (turtle-shaped mass), lao zhai (consumptive disease), chuan shen (transmissible corpse disease), etc., leading to death or destruction of the family. The harm caused by insects is so cruel. Therefore, the sages used methods to kill them; if humans cannot kill the insects, the insects will surely kill humans.
(Zhang Zhongjing) Treats Shaoyin Jueyin syndrome of Shanghan (Cold Damage), cold jue with vomiting of roundworms. (In Shanghan, Zang jue leads to death. Zang jue is characterized by a faint pulse and cold extremities. After seven or eight days, the skin becomes cold, irritability occurs, and there is no moment of rest. Hui jue [roundworm jue] occurs when roundworms ascend into the epigastrium causing vexation, which stops after a while. Eating causes vomiting and further vexation because the roundworms emerge upon smelling food. This is due to cold in the viscera, and Wumei Wan should be used.)
Wumei (300 pieces), Xixin (Asari Radix), Guizhi (Cinnamomi Ramulus), Renshen (Ginseng Radix), Fuzi (Aconiti Lateralis Radix Praeparata), Huangbai (Phellodendri Cortex, 6 liang), Huanglian (Coptidis Rhizoma, 1 jin), Ganjiang (Zingiberis Rhizoma, 10 liang), Chuanjiao (Sichuan Pepper, sweat removed), Danggui (Angelicae Sinensis Radix, 4 liang). Soak Wumei in Kujiu (vinegar) overnight, remove pits, steam until cooked, mix with other herbs, and form honey pills.
This formula acts on the Foot Yangming and Foot Jueyin meridians. Roundworms subside when encountering sourness, hence Wumei's sourness is used to subdue them; roundworms settle when encountering bitterness, hence the bitterness of Huanglian and Huangbai is used to calm them; it also has the effect of astringing Lung Qi. (Vomiting of roundworms is due to Stomach cold, forming Hui jue. It is appropriate to use Lizhong Tang plus fried Chuanjiao (5 grains) and Binglang (Arecae Semen, 0.5 fen), taken with Wumei Wan. Cheng Jiaoqian stated: Wumei Wan adds slight bitter-cold herbs to the sour-pungent Liver-entering formulas, accepting the rebellious Yang pathogen and guiding it downward. Named "Calming Roundworms," it actually "Calms the Stomach," thus also treating chronic dysentery. Any condition of lower diarrhea due to failure of Yin and Yang to connect smoothly can be covered by this formula. The Classic states: Whenever Yin and Yang fail to connect smoothly, Jue occurs. Fang Xingzhong stated: The Classic says, the three Hand-Yin meridians run from abdomen to hand, the three Hand-Yang meridians from hand to head, the three Foot-Yang meridians from head to foot, and the three Foot-Yin meridians from foot to abdomen. Thus, all six meridians connect at the hands and feet. When Yang qi sinks inward and fails to connect smoothly with Yin qi, cold extremities result.)