穿踝疽，乃足三阴湿热下流停滞而成。初起内踝肿痛，疼彻骨底，举动艰辛，甚则串及外踝通肿。有头者
属阳，易破，无头者属阴，难溃。此二者，初起必寒热交作，宜荆防败毒散加牛膝散之，日久脓成胀痛者针之。
腐而不敛孔大者，玉红膏培之；形体虚弱者补之。此症若不早治，因循致成废疾也有矣。
荆防败毒散（见时毒门）
玉红膏（见肿疡门）
大麻风症，乃天地间异症也。但感受不同，有体虚之人因骤被阴阳暴晒、露雾风雨之气所侵，感之不觉，
未经发泄，凝滞肌肤，积久必作。又有房欲后体虚为风邪所袭，或露卧当风，睡眠湿地；或洗浴乘凉，希图快
意；……此等相感俱能致之。其患先从麻木不仁，次发红斑，久则破烂，浮肿无脓。又谓皮死麻木不仁，肉死
刀割不痛，血死破烂流水，筋死指节脱落，骨死鼻梁崩塌。有此五症，俱为不治。又曰心受之先损于目，肝
受之面发紫泡，脾受之遍身如癣，肺受之眉毛先脱，肾受之足底先穿，又为五败症也。总皆风湿相乘，气血凝
滞，表里不和，脏腑痞塞，阳火所变，此其根蒂也。初起麻木不仁，肌肉未死者，宜万灵丹洗浴发汗，以散凝
滞之风；后服神应养真丹加白花蛇等分，久服自愈。年久肌破肉死者，先用必胜散疏通脏腑；次服万灵丹，每
日酒化一丸，通适血脉，服至一月，换服苦
参丸，轻者半年，重者一载渐愈。或兼服酒药，忌戒房事、浓味、动风等件，可保终年不发矣。
万灵丹（见痈疽肿疡门）
治大麻风初起麻木不仁，或既久皮肤破裂、手足拳挛，肢体不便，但未指脱足穿者，并宜服之。
必胜散
必胜散中用大黄 白丑槟榔共粉霜
姜汁砂糖同末服 管教患者渐安康
治大麻风血热秘结，脏腑不通，宜用此药利之。
大黄 槟榔 白牵牛（各一钱） 粉霜（一钱五分）
上各为细末，年壮者作五服，中年久虚者作七服。用生姜四两捣汁，赤砂糖三钱，加水一大杯，三味和匀，
临睡时腹中稍空、顿温通口服之即睡；至三更，遍身麻木如针刺，头、目、齿缝俱痛，此药寻病之功已达，行
出大、小二便，或青白黑黄，又或红虫之类，此乃病根也，一月内服药三次渐痊，眉发俱生，肌肤如旧。齿缝
有血，宜漱后药。
漱药方
漱药方中有二般 贯众黄连一处攒
水煎加入些些片 止血何愁甚不安
贯众、黄连各三钱，水二钟，煎一半，入冰片少许，每日陆续漱之，其血自止，兼忌动风、油腻之物。
苦参丸
苦参丸内药多般 品味难将一一刊
新久麻风诸坏症 将来久服自能安
治大麻风毋分新久，穿破溃烂，老幼俱可服之。
苦参（一斤） 大风子（肉六两） 荆芥（十六两） 防风 白芷（各六两） 全蝎 何首乌 白附子
枸杞子 威灵仙 当归 大胡麻
川芎 蒺藜 大皂角 川牛膝 牛蒡子 独活（各五两） 蔓荆子 风藤 羌活 连翘 苍术 天麻 杜仲
草乌（泡去皮尖） 甘草（各三两） 人参（一两） 砂仁（二两） 白花蛇（二两，切片炙黄）
上药共为细末，醋打老米糊为丸，梧桐子大，每服三、四十丸，温酒食前后任下。避风、忌口为妙。
麻风药酒方
麻风酒膝术防归 苦杞姜秦虎节随
羌活萆麻并鳖甲 茅根加上效堪推
防风 当归 虎骨 秦艽 羌活 苦参 牛膝 姜蚕 松节 鳖甲 苍术 枸杞子 白茅根（各二两）
萆麻子仁（一两）
用好雪酒二十五斤，用药袋盛浸酒内，封坛口，煮香二枝取起，水内浸一伏时，取服数杯自效。
雄硫散
雄硫散内凤凰皮 山甲相兼滑石随
桃肉共和猪胆汁 眉毛脱落擦之宜
治大麻风眉毛、须、发脱落作痒者，宜此药擦之。
雄黄 硫黄 凤凰皮（即雏鸡壳，烧黄存性，各五钱） 穿山甲（十片，炒黄） 滑石（一两）
上各为细末，用半油核桃肉一两捣烂，同公猪胆汁一个同前药和匀，用青纱包药擦之。日用三次，其发渐
生如旧。
又擦麻风病面生紫块疙瘩。方用∶穿山甲灰炒，川椒为末各二钱，生姜汁、土大黄根二汁调稠绢包擦患上，
如久药干，加水调擦亦效。忌动风、发物等件。
穿踝疽，是由于足三阴经（肝、脾、肾经）的湿热之邪下注并停滞在体内而形成的。初期表现为内踝部位肿胀疼痛，疼痛剧烈直达骨底，活动困难，严重时肿胀会蔓延至外踝，导致整个脚踝都肿起来。有脓头者属于阳证，容易破溃；没有脓头者属于阴证，难以化脓溃破。这两种情况在初期必然会出现寒战与发热交替的症状，适宜服用荆防败毒散并加入牛膝来疏散邪气；如果日久脓液形成且出现胀痛，则应当用针刀刺破排脓。对于腐烂后伤口久不愈合、孔洞较大的情况，使用玉红膏进行养护促进生肌；对于身体形体虚弱者，则采用补益疗法。此症如果不尽早治疗，因拖延延误而导致成为残疾的情况也是有的。
荆防败毒散（详见“时毒门”章节）
玉红膏（详见“肿疡门”章节）
大麻风病，是天地间一种特殊的疾病。但致病原因各不相同：有的是体质虚弱之人，突然遭受阴阳暴晒、露雾风雨等邪气的侵袭，当时感觉不到不适，未能及时发泄排出，导致邪气凝滞于肌肤之间，积聚久了必然发病。又有的是在房事之后身体虚弱，被风邪所袭击，或者露天睡觉迎着风，睡在潮湿的地方；或者是洗澡后乘凉，贪图一时的舒适快感；……这些感受邪气的方式都能导致该病发生。其症状起初先从皮肤麻木不知痛痒开始，接着出现红斑，时间久了则皮肤破烂，浮肿但没有脓液。又说：皮死表现为麻木不知痛痒，肉死表现为用刀割也不觉得痛，血死表现为皮肤破烂流水，筋死表现为指节脱落，骨死表现为鼻梁崩塌。出现这五种症状，都属于无法治愈的绝症。又说：心脏受邪首先损害眼睛，肝脏受邪面部出现紫色水泡，脾脏受邪全身像癣一样，肺脏受邪眉毛首先脱落，肾脏受邪脚底首先穿孔，这又被称为五败症。总的来说，都是风湿相互侵犯，气血凝滞，表里不和，脏腑痞塞不通，由阳火变化所致，这是疾病的根本原因。初期出现麻木不知痛痒，肌肉尚未坏死的，适宜用万灵丹洗浴以发汗，从而消散凝滞的风邪；随后服用神应养真丹，并加入白花蛇等量药材，长期服用可自行痊愈。如果是患病多年肌肉破裂坏死的，先用必胜散疏通脏腑；接着服用万灵丹，每天用酒化开一丸服用，以通畅血脉，服用一个月后，换服苦参丸，轻症半年，重症一年可逐渐痊愈。或者兼服药酒，忌戒房事、浓味食物、动风食物等，可以保证终身不再发作。
万灵丹（详见“痈疽肿疡门”章节）
主治大麻风初起出现的麻木不知痛痒，或者病程已久导致皮肤破裂、手足蜷曲挛缩、肢体不便，但尚未出现手指脱落或脚底穿孔的情况，都适宜服用此药。
必胜散
必胜散中使用了大黄、白牵牛、槟榔共同研磨成粉霜。
用姜汁和砂糖同药末一起服用，能保证患者逐渐恢复健康。
主治大麻风引起的血热秘结，脏腑不通畅，适宜用此药来通利大便。
组成：大黄、槟榔、白牵牛（各一钱），粉霜（一钱五分）。
以上药物分别研为细末，年轻力壮的人分五次服用，中年体虚久病的人分七次服用。用生姜四两捣取汁液，赤砂糖三钱，加水一大杯，将这三味东西混合均匀，在临睡前腹部稍空的时候，温热顿服，服后即睡；到了三更天，全身麻木如针刺般，头、眼、牙齿缝隙都疼痛，这说明药效已经到达病灶，通过大小便排出青色、白色、黑色、黄色等大粪，或者红色的虫类之类，这就是病根所在。一个月内服药三次即可逐渐痊愈，眉毛头发重新生长，肌肤恢复如初。如果牙齿缝隙出血，适宜漱口使用下面的药物。
漱药方
漱药方中有两种主要药材：贯众和黄连放在一起。
用水煎煮，加入少许冰片。止血不用担心病情不安稳。
组成：贯众、黄连各三钱，水两钟，煎至一半水量，加入少许冰片，每日陆续漱口，出血自然停止，同时忌食动风和油腻的食物。
苦参丸
苦参丸内的药材种类繁多，品味难以一一刊印出来。
无论是新近还是久患的大麻风各种严重病症，将来长期服用自然能安宁康复。
主治大麻风不分新久，凡是穿破溃烂的，老人小孩都可以服用。
组成：苦参（一斤），大风子仁（六两），荆芥（十六两），防风、白芷（各六两），全蝎、何首乌、白附子、枸杞子、威灵仙、当归、大胡麻、川芎、蒺藜、大皂角、川牛膝、牛蒡子、独活（各五两），蔓荆子、风藤、羌活、连翘、苍术、天麻、杜仲、草乌（炮制去皮尖）、甘草（各三两），人参（一两），砂仁（二两），白花蛇（二两，切片炙黄）。
以上药物共同研为细末，用醋打老米糊作为粘合剂制成梧桐子大小的药丸，每次服用三四十丸，温酒送服，饭前饭后均可。注意避风、忌口为好。
麻风药酒方
麻风药酒包含牛膝、苍术、防风、当归、苦参、枸杞、干姜、秦艽、虎骨、桑节（松节）、羌活、萆薢、麻黄、鳖甲、白茅根等。
组成：防风、当归、虎骨、秦艽、羌活、苦参、牛膝、姜蚕（僵蚕）、松节、鳖甲、苍术、枸杞子、白茅根（各二两），蓖麻子仁（一两）。
用好雪酒二十五斤，将药物装在袋子里浸泡在酒中，封好坛口，煮香两根树枝后取出，放入水中浸泡一个时辰（约两小时），取出饮用几杯自见功效。
雄硫散
雄硫散内含有凤凰皮（鸡壳）、穿山甲、滑石相随。
桃肉与猪胆汁混合，眉毛脱落者适宜擦拭此药。
主治大麻风导致的眉毛、胡须、头发脱落且瘙痒的情况，适宜用此药擦拭。
组成：雄黄、硫黄、凤凰皮（即雏鸡壳，烧至焦黄保留药性，各五钱）、穿山甲（十片，炒黄）、滑石（一两）。
以上药物分别研为细末，用半个油核桃肉一两捣烂，同公猪胆汁一个与前药混合均匀，用青纱包裹药物擦拭患处。每天使用三次，头发会逐渐再生如旧。
另外擦拭麻风病面部产生的紫色块状疙瘩。方子用：穿山甲灰炒制，川椒研末，各二钱，用生姜汁、土大黄根汁调成稠状，用绢布包裹擦拭患处，如果时间久了药干了，加水调匀擦拭也有效。忌食动风和发物等。
Chuanhuai Ju (Penetrating Ankle Abscess) is caused by damp-heat from the Three Yin Meridians of the Foot (Liver, Spleen, Kidney) flowing downward and stagnating in the body. Initially, there is swelling and pain at the medial malleolus, with pain penetrating to the bone base, making movement difficult; severely, it spreads to the lateral malleolus causing total ankle swelling. Cases with a head are Yang syndromes, easy to ulcerate; those without a head are Yin syndromes, difficult to suppurate. Both types initially present with alternating chills and fever, suitable for treating with Jingfang Baidu San (Astragalus and Saposhnikovia Decoction) added with Achyranthes Root (Niuxi) to disperse pathogens. If pus forms after a long time causing distending pain, it should be punctured with a needle. For rotting wounds that fail to heal with large holes, Yuhong Gao (Jade Red Ointment) is used to nourish tissue; for patients with weak physical constitutions, tonification methods are applied. If this condition is not treated early, neglect can lead to disability.
Jingfang Baidu San (See "Shidu Men" chapter)
Yuhong Gao (See "Zhongyang Men" chapter)
Dama Feng (Leprosy/Mal de Choeur) is a special disease in heaven and earth. Etiologies vary: some individuals with weak constitutions are suddenly invaded by extreme sun exposure, dew, fog, wind, or rain, feeling no immediate discomfort, failing to vent the pathogen, leading to stagnation in skin and muscles, which eventually manifests as disease. Others suffer invasion by wind pathogens after sexual intercourse due to weakness, or sleep exposed to wind outdoors, or on damp ground; or bathe and cool off seeking temporary pleasure... All these modes of pathogen acquisition can cause the disease. Symptoms begin with numbness and insensitivity, followed by red spots; over time, the skin breaks down, swells without pus. It is said: "Skin death" presents as numbness; "Flesh death" as insensitivity to knife cuts; "Blood death" as broken skin oozing fluid; "Tendon death" as finger joint detachment; "Bone death" as collapse of the nasal bridge. These five conditions are all incurable. Furthermore: Heart involvement first damages the eyes; Liver involvement causes purple blisters on the face; Spleen involvement causes body-wide lesions resembling tinea; Lung involvement causes eyebrow loss first; Kidney involvement causes perforation of the soles first. These are called the Five Failures. Generally, this is caused by Wind-Dampness attacking each other, Qi and Blood stagnation, disharmony between exterior and interior, obstruction of Zang-Fu organs, and transformation by Yang Fire, which constitutes the root of the disease. In the initial stage of numbness where flesh is not yet dead, Wanling Dan (Ten Thousand Spirit Pill) bath and sweat induction are suitable to dissipate stagnant wind; subsequently, Shenying Yangzhen Dan (Divine Response Nourishing True Pill) added with equal parts of Agkistrodon (Baihua She) should be taken long-term for self-healing. For chronic cases with broken skin and dead flesh, Biseng San (Invincible Powder) is used first to unblock Zang-Fu; then Wanling Dan is taken, one pill dissolved in wine daily to unblock blood vessels. After one month, switch to Kushen Wan (Sophora Pill). Mild cases improve in half a year, severe cases in one year. Alternatively, medicated wine can be taken concurrently. Abstinence from sexual activity, rich flavors, and wind-aggravating foods ensures lifelong remission.
Wanling Dan (See "Yongju Zhongyang Men" chapter)
Indicated for initial Dama Feng with numbness, or long-standing cases with skin rupture, clenched hands and feet, limb inconvenience, but without finger detachment or sole perforation.
Biseng San (Invincible Powder)
Biseng San uses Rhubarb (Dahuang), White Morning Glory Seed (Bai Qian Niu), and Areca Nut (Bing Lang) ground into powder.
Taken with Ginger Juice and Rock Sugar, it ensures gradual patient recovery.
Indicated for Dama Feng with blood heat and constipation, unblocking Zang-Fu organs.
Composition: Rhubarb, Areca Nut, White Morning Glory Seed (each 1 qian), Mercury Subchloride (Fenshuang, 1.5 qian).
Grind each into fine powder. Young and strong persons take five doses; middle-aged and weak persons take seven doses. Use four liang of fresh ginger juice, three qian of brown sugar, add one large cup of water, mix well. Take warm on an empty stomach before sleep; by the third watch (midnight), the whole body feels numb like needle pricks, head, eyes, and teeth hurt. This indicates the medicine has reached the disease site. Large and small bowel movements will expel green, white, black, yellow stools, or red worms, which are the disease roots. Three doses within a month lead to gradual cure, eyebrows and hair regrow, skin returns to normal. If gums bleed, use the following mouthwash.
Mouthwash Formula
The Mouthwash Formula contains Cyperus (Guanzhong) and Coptis (Huanglian).
Boil in water, add a little Borneol (Bingpian). Stop bleeding and alleviate distress.
Composition: Cyperus, Coptis (each 3 qian), two zhong of water, decoct to half volume, add a little Borneol. Rinse mouth continuously daily; bleeding stops naturally. Avoid wind-aggravating and greasy foods.
Kushen Wan (Sophora Pill)
Kushen Wan contains many ingredients, too numerous to list fully.
For new or old Dama Feng with various severe symptoms, long-term use brings peace.
Indicated for Dama Feng regardless of duration, with ulcers and rotting, suitable for all ages.
Composition: Sophora Root (Kushen, 1 jin), Jatropha Seed (Dafengzi, 6 liang), Schizonepeta (Jingjie, 16 liang), Saposhnikovia (Fangfeng), Angelica Dahurica (Baizhi, each 6 liang), Scorpion (Quanxie), Polygonum Multiflorum (Heshouwu), Aconitum Kusnezoffii (Baifuzi), Goji Berry (Gouqizi), Clematis (Weilingxian), Chinese Angelica (Danggui), Sesame (Dahuma), Ligusticum (Chuanxiong), Tribulus (Jili), Soap Pod (Da Zaojiao), Achyranthes Bidentata (Chuanniuxi), Arisaema (Niubangzi), Angelica Pubescens (Duhuo, each 5 liang), Vitex (Manjingzi), Uncaria (Fengteng), Notopterygium (Qianghuo), Forsythia (Lianqiao), Atractylodes (Cangzhu), Gastrodia (Tianma), Eucommia (Duzhong), Aconitum (Caowu, processed peeled), Licorice (Gancao, each 3 liang), Ginseng (Renshen, 1 liang), Amomum (Sharen, 2 liang), Agkistrodon (Baihua She, 2 liang, sliced and roasted).
Grind all into fine powder, make pills using vinegar and old rice paste, size of paulownia seeds. Take 30-40 pills with warm wine before or after meals. Avoid wind and dietary restrictions are advisable.
Leprosy Medicated Wine Formula
Leprosy Wine includes Achyranthes, Atractylodes, Saposhnikovia, Angelica, Sophora, Goji, Ginger, Gentian, Tiger Bone, Pine Joint, Notopterygium, Dioscorea Hypoglauca, Turtle Shell, Imperata, etc.
Composition: Saposhnikovia, Angelica, Tiger Bone, Gentian Macrophylla (Qinjiao), Notopterygium, Sophora, Achyranthes, Bombyx Batryticatus (Jiangcan), Pine Joint, Turtle Shell, Atractylodes, Goji, Imperata Cylindrica (Baimaogen, each 2 liang), Ricinus Communis (Bimazi, 1 liang).
Soak herbs in 25 jin of good Xue Wine in a bag, seal jar, boil with two incense sticks until fragrant, remove sticks, soak in water for one fushi (approx. 2 hours), then drink several cups for effect.
Xiong Liu San (Realgar and Sulfur Powder)
Xiong Liu San contains Phoenix Skin (Chicken Shell), Pangolin Scales, and Talcum.
Mixed with Peach Kernel and Pig Gallbladder bile, suitable for rubbing on fallen eyebrows.
Indicated for Dama Feng with itching and loss of eyebrows, beard, and hair.
Composition: Realgar (Xionghuang), Sulfur (Liuhuang), Phoenix Skin (burnt to preserve nature, each 5 qian), Pangolin Scales (fried yellow, 10 slices), Talcum (1 liang).
Grind into fine powder, mix with 1 liang of oil walnut meat pounded into paste and one male pig gallbladder bile. Wrap in green gauze and rub on affected areas. Apply three times daily; hair gradually regrows.
Another formula for purple lumps on the face in Leprosy: Charred Pangolin Scale ash and Sichuan Pepper powder (each 2 qian), mixed with Ginger Juice and Rhubarb Vine (Tudahuang) root juice to a thick consistency. Rub on affected area with silk cloth. If dry, add water and rub again. Avoid wind-aggravating and stimulating foods.