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To treat variola (smallpox) presenting with black depression, or red-purple-black macules, accompanied by teeth grinding, aversion to cold, and chills.
Renya (Human Tooth) (From naturally shed teeth, calcined until the original nature is preserved, quenched in juice of Chive Rhizome [Jiucai Zi], large teeth quenched three times, small teeth twice, ground into powder). Shexiang (Musk [Moschus]) (1 fen, or add Hongqu [Red Yeast Rice] 2 fen). Mix with blood from Rooster Comb [Jiguanxue] to form a paste. Take half a cup of milk and half a cup of wine, decoct with white part of Scallion Stem [Congbai], mix well, and administer orally. The dosage should only be 2-3 fen; do not overdose, as excessive intake will cause all Yang Qi to dissipate to the exterior. It treats variola lesions that are ulcerated and lack color, due to internal excess of Yin Qi leading to interior cold and loose stools; urgently administer Sijunzi Tang (Four Gentlemen Decoction) added with Chuanxiong Rhizome [Chuanxiong] and Angelicae Sinensis Radix [Danggui].

To treat variola black depression approaching death.
Another prescription adds a small amount of Shexiang (Musk [Moschus]) and Pian Nao (Borneol [Bingpian]).
Take feces from a healthy child, dry it in the shade before dusk on the last day of the twelfth lunar month. Use two silver jars, fit them together top and bottom, seal firmly with salt mud, heat until red-hot, take out, grind into powder, and take 1 qian mixed with honey water.

To treat variola that fails to erupt due to wind-cold, or presents with red-purple color, or convulsions and tremors.
Jiangcan (Silkworm [Bombyx Batryticatus]) (washed with wine). Quanxie (Scorpion [Scorpio]) (washed with wine, remove legs and tail). Gancao (Licorice Root [Gancao]). Zicao (Arnebia Root / Bugloss Root [Zicao]). Baifuzi (Aconitum Bulb [Baifuzi]) (bitter taste, inner white part is authentic). Mahuang (Ephedra Herb [Mahuang]) (each 5 qian). Chuanshanjia (Pangolin Scale [Chuanshanjia]) (stir-fried and powdered, 2.5 qian). Chantui (Cicada Slough [Chantui]) (remove head and legs, 2 qian). Grind into powder. Separately, take Honghua (Safflower [Honghua]) and Zicao (Arnebia Root / Bugloss Root [Zicao]), each 1 liang, and one bell of good wine, decoct until less than half remains, strain, add 5 liang of honey, simmer slowly over low fire until it forms beads when dropped in water. Form pills the size of a longan fruit. Take one pill per dose, administered with Decoction of Centipede Grass [Dengxincao].

To treat variola apex presenting with red-purple-black depression.
Jiangcan (Silkworm [Bombyx Batryticatus]) (5 qian, washed with wine). Quanxie (Scorpion [Scorpio]) (washed with wine, remove head and tail). Mahuang (Ephedra Herb [Mahuang]) (do not remove nodes, each 1 liang). Baifuzi (Aconitum Bulb [Baifuzi]) (processed, upper white part is best, 5 qian). Zicao (Arnebia Root / Bugloss Root [Zicao]) (1 liang). Chuanshanjia (Pangolin Scale [Chuanshanjia]) (3 qian). Chantui (Cicada Slough [Chantui]) (3 qian, washed with wine, remove head and tail). Chansu (Toad Venom [Chansu]) (1 qian). Grind into powder. Separately, take 1 liang of Zicao (Arnebia Root / Bugloss Root [Zicao]), decoct, strain, and boil into a paste. Add 2 liang of honey and half a bell of good wine, mix with the Zicao paste and the aforementioned powder, form pills the size of mung beans. For children aged 3-4 years, take one pill per dose. If the variola is red-purple and black-depressed, administer with Zicao Tang (Bugloss Decoction); if the color is pale, thin, and gray-depressed, dissolve and administer with fine wine.