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After the resolution of smallpox, if residual toxins remain unresolved and manifest as urticaria (a skin condition characterized by itchy wheals), known as "yin," the rash appears faintly as raised bumps, with itching intensifying upon scratching. The treatment should involve internal administration of Jiedu Fangfeng Tang (Detoxifying Saposhnikovia Decoction) and external washing with fresh clam water. If the rash is red and intensely itchy, bleeding upon scratching yet still itching, this is termed Zidian Feng (Purple Spot Wind). It is appropriate to use herbs such as Jingjie (Schizonepetae Herba), Fangfeng (Saposhnikoviae Radix), Caohuma (Sesami Fructus), Shengdihuang (Rehmanniae Radix), Niubangzi (Arctii Fructus), Chishao (Paeoniae Radix Rubra), Danpi (Moutan Cortex), and Lianqiao (Forsythiae Fructus). Sesame treats thirty-six types of wind disorders, but for itching, it is indispensable. The so-called "zhen" (rash) refers to dot-like marks on the skin resembling mosquito or flea bites, or similar to small scabies lesions. Internal administration of Shengma Gegen Tang (Cimicifugae et Puerariae Decoction) is suitable, adjusting the degree of dispersing and resolving according to the severity of the condition.

In cases where fever persists from the onset of smallpox until after recovery without subsiding, the toxin resides in the Heart. However, there are two patterns: excess and deficiency. If there is difficulty in defecation, dark urine, normal appetite but with irritability and thirst, this indicates Excess Heat; one should first resolve the interior heat, and the exterior heat will naturally resolve. If defecation is not completely blocked, urine is not dark, the patient sits and stands restlessly with trembling, and food intake is poor, this indicates Deficiency Heat. Baoyuan Tang (Preserve the Origin Decoction) is used, supplemented with Maidong (Ophiopogonis Radix) and Zhimu (Anemarrhenae Rhizoma). In severe deficiency, charred Ganjiang (Zingiberis Rhizoma) or a small amount of Shufuzi (Aconiti Lateralis Radix Praeparata) is added to guide fire back to its source. Furthermore, when smallpox has just healed, Ying and Wei (Nutritive and Defensive Qi) are deficient. If precautions are neglected and seasonal climatic changes occur, pathogenic qi from all directions may invade due to deficiency, leading to Stroke (Zhongfeng). Symptoms include generalized cyanosis, drooling, convulsions of hands and feet, and opisthotonos. Treatment involves administering Xiaofeng San (Wind-Dispersing Powder) two to three doses, which may also resolve concurrent urticaria. Additionally, post-scabbing neglect may lead to imbalance of Yin and Yang, susceptibility to Wind-Cold, stagnation of Cold transforming into Heat, excessive Heat generating Phlegm, and Wind-Phlegm attacking. With hyperactive Heart Fire and Liver Fire, Phlegm rises and obstructs the Heart orifices, causing sudden collapse and loss of consciousness, resembling Epilepsy or Mania. Treatment focuses on resolving Phlegm, clearing Heat, and calming the Heart. However, following significant Qi and Blood depletion, Wind and Fire are often false manifestations; thus, treatment should primarily address the root. For congenital Kidney deficiency, Dihuang Wan (Rehmannia Pill) is indicated; for acquired Heart and Spleen deficiency, Shiquan Tang (Complete Ten Tonics Decoction) is indicated.

Residual heat is essentially Deficiency Heat. Once smallpox toxins are resolved, both Yin and Yang are depleted; the post-smallpox state is akin to the postpartum period. This aligns with the concept of "fire arising from emptiness." Fever typically occurs in the afternoon, evidenced by flushed cheeks. Severe deficiency causes fever; intense heat leads to delirium and irritability, which is inevitable. One must not mistakenly treat this as Excess Heat. This floating of Deficient Yang is termed "Strong Yang." Throughout the course, Baoyuan Tang combined with Siwu Tang (Four Substances Decoction) should be modified appropriately. Preemptive conditioning is crucial; otherwise, prolonged illness may lead to Infantile Malnutrition (Gan Syndrome), sore throat, hoarseness, ocular Gan erosion, wind-induced convulsions and tendon pulling, and gangrenous stomatitis (Zouma Yagan). If oral Gan is severe enough to prevent eating and topical medication is ineffective, it indicates rotting of the Stomach, which is incurable.