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The classic texts state: The Large Intestine is the official responsible for transmission, where changes and transformations occur. It is further stated that the Hui Chang (Revolving Intestine) is located to the left of the umbilicus, revolving sixteen times, with a width of four cun, a diameter of one cun and one-third cun, and a length of two zhang and one chi, capable of holding one dou of grain and seven sheng and half a sheng of water. It is also stated that the Guang Chang (Broad Intestine) attaches to the spine to receive the Revolving Intestine; this is the pathway for expelling waste and filth. The Broad Intestine is eight cun wide, two cun and two-thirds cun in diameter, and two chi and eight cun long, capable of holding nine sheng, three he, and one-eighth he of grain. This meridian is characterized by abundant Qi and scarce Blood. The Nan Jing states: The Large Intestine weighs two jin and twelve liang, and the An Men (Anus) weighs twelve liang.

Zhang Jiebin stated: Regarding the Hui Chang, its name derives from its revolved and folded structure; the Guang Chang is the larger portion of the Hui Chang; the Zhi Chang (Straight Intestine) is the terminal segment of the Guang Chang, connecting downwards to the Anus.

The Hand-Yangming Large Intestine Fu Meridian originates at the tip of the radial side of the index finger, follows the upper medial border of the finger, emerges between the two bones at Hegu (LI4), ascends into the space between the two tendons, follows the upper lateral border of the forearm, enters the lateral aspect of the elbow, ascends along the anterior lateral border of the upper arm, reaches the shoulder emerging before the anterior border of the acromion, ascends above the meeting point of the vertebral column, descends into the Supraclavicular Fossa (Quepen), connects with the Lung, passes downward through the diaphragm, and belongs to the Large Intestine. Its branch arises from the Supraclavicular Fossa, ascends to the neck, penetrates the cheek, enters the lower teeth, returns to emerge flanking the mouth, crosses at Renzhong (GV26)—left crossing right, right crossing left—and ascends to flank both sides of the nostrils.

The Yangming Hand-Large Intestine meridian starts at Shangyang (LI1) on the inner side of the index finger, follows the upper border of the finger out to Hegu (LI4), traverses the gap between the bones and tendons along the forearm, enters the lateral elbow, follows the lateral upper arm, passes the anterior border of the shoulder and beside the vertebral column, descends from the shoulder into the Supraclavicular Fossa, connects with the Lung, passes downward through the diaphragm, and belongs to the Large Intestine. The branch rises straight from the Supraclavicular Fossa to the neck, obliquely penetrates the anterior cheek to the lower teeth, circles out to cross Renzhong (GV26) left and right, and ascends to flank the nostrils, entering Yingxiang (LI20).

[Annotation] The meridians of the Hand-Yangming Large Intestine originate at the end of the medial border of the index finger. The phrase "emerges from the thumb" refers to Shaoshang (LU11) of the thumb, which is the collateral branch of this meridian. Its branch directly emerges from the tip of the index finger to connect with Shangyang (LI1) of the Hand-Yangming Large Intestine Meridian; hence it is said to "originate at the ends of the index and thumb fingers." From Shangyang (LI1), following the upper border of the index finger, are Erjian (LI2) and Sanjian (LI3). From Sanjian (LI3), emerging between the two bones, is Hegu (LI4). From Hegu (LI4) ascending between the two tendons is Yangxi (LI5). From Yangxi (LI5), following the upper lateral border of the forearm to Pianli (LI6), Wenliu (LI7), Xia Lian (LI8), Shang Lian (LI9), and Sanli (ST36/LI10 context implies ST36 but text says Sanli which usually refers to Zusanli ST36, however in LI channel context often refers to specific points or is a textual variation, here strictly translating as Sanli), are the points. From Sanli entering the lateral aspect of the elbow is Quchi (LI11). From Quchi (LI11) ascending to the anterior lateral border of the upper arm are Zhou Liao (LI12), Wuli (LI13), and Bi Nao (LI14). From Bi Nao ascending to the shoulder is Jianyu (LI15). From Jianyu (LI15) emerging before the anterior border of the acromial bone is Gugu (LI16). From Gugu (LI16) ascending above the meeting of the vertebral column, it meets Dazhui (GV14) of the Du Mai; from Dazhui (GV14) of the Du Mai, it enters and intersects with Quepen (ST12) of the Foot-Yangming Stomach Meridian. Connecting with the Lung, passing downward through the diaphragm, and belonging to the Large Intestine refers to the branch arising from Quepen, ascending to the neck, again following Tianding (LI17) of this meridian, penetrating the cheek to Futu (LI18). From Futu (LI18) entering the lower teeth is Heliao (LI19); from Heliao (LI19) returning to emerge flanking the mouth and crossing at Renzhong (GV26)—left crossing right, right crossing left—ascending to flank the nostrils to Yingxiang (LI20) to conclude, thereby connecting with the Foot-Yangming Stomach Meridian.