主寒冷虚损，五十年心腹积聚百病，邪气往来，厥逆抢心。痹顽羸瘦骨立，不能食，破
积聚方∶
乌头（十五分，炮，去皮） 人参（五分） 生姜（二两） 前胡 蜀椒（去目闭口者
汗） 黄
芩白术 半夏（洗） 黄连 吴茱萸 龙骨 白头翁 干姜 细辛 桔梗 紫菀 芎 浓
朴（
上二十二味，捣筛为末，炼蜜和丸如梧子大，酒服十丸，日三夜一，以知为度。
破积聚，治积结冷聚，阳道弱，大便有血，妇人产后出血不止方∶
乌头（十五分，炮，去皮） 大黄 干姜 浓朴（炙） 吴茱萸 芍药 前胡 芎 当
归
参紫
菀甘草（炙，各一两）
上一十八味，捣筛为末，炼蜜和丸如梧子大，酒服十丸，日三服，渐渐加之。
主风劳四十年癖绝冷，并主咳逆上气方∶
人参 桂心 吴茱萸 乌头（炮，去皮） 矾石（烧，等分）
上五味，捣筛为末，炼蜜和丸如梧子大，酒服三丸，日再，以知为度。
主毒冷方∶
矾石（烧） 桔梗 皂荚（炙，去皮子） 干姜 附子（炮，去皮） 吴茱萸（等分）
上六味，捣筛为末，炼蜜和丸如梧子大，饮服三丸，日再。稍加，以知为度。
论一首 方三十五首与第二十二卷通
论曰∶既得药力，诸 并遣。石忽发动，须知解方。故次立解散方焉。一一依其诊候而
用之，万不失一。夫脉或洪或实，或断绝不足，欲似死脉，或细数，或弦快，其所犯非一故
也。脉无常，投医不能识也。热多则弦快，有癖则洪实，急痛则断绝。凡寒食药热率常如是，
自无所苦，非死候也。动从节度，则不死矣。不从节度，则死矣。欲服散者，宜诊脉审正其
候，尔乃毕愈。脉沉数者难发，难发当数下之。脉浮大者易发也。人有服散两三剂不发者，
此人脉沉难发。发不令人觉，药势已行。不出形于外，但以药治于内。欲候知其力，人进食
多，一候也。颜色和悦，二候也。头面身体瘙痒，三候也。涩涩恶风，四候也。厌厌欲寐，
五候也。诸有此证候者，皆药内发五脏，但如方法服药。宜数下之，内虚自当发也。
Mainly treats deficiency and damage caused by cold, as well as various diseases involving accumulations and masses in the heart and abdomen lasting for fifty years, where pathogenic qi moves back and forth, leading to cold extremities (Jue Ni) and cold rushing to the heart. The body presents with bi syndrome (obstruction syndrome), numbness, emaciation, skeletal appearance, and inability to eat.
Formula for breaking down accumulations:
Aconiti Lateralis Radix Praeparata (Wutou, 15 fen, processed, skin removed) Ginseng Radix (Renshen, 5 fen) Zingiberis Rhizoma Recens (Shengjiang, 2 liang) Peucedani Radix (Qianhu) Zanthoxyli Fructus (Shujiao, remove eyes and closed-mouth ones) Scutellariae Radix (Huangqin) Atractylodis Macrocephalae Rhizoma (Baizhu) Pinelliae Rhizoma Preparatum (Banxia, washed) Coptidis Rhizoma (Huanglian) Evodiae Fructus (Wuzhuyu) Os Draconis (Longgu) Pulsatillae Radix (Baitouweng) Zingiberis Rhizoma (Ganjiang) Asari Radix et Rhizoma (Xixin) Platycodonis Radix (Jiegeng) Asteris Tatarici Radix (Ziwan) Chuanxiong Rhizoma (Chuanxiong) Magnoliae Officinalis Cortex (Houpo)
The above twenty-two ingredients are crushed, sifted into powder, mixed with refined honey to form pills the size of a wu zi (Cocculus trilobus seed). Take ten pills with wine, three times during the day and once at night, until effective.
Formula for breaking down accumulations, treating cold accumulations and结聚 (jiejie), weak yang pathway, hematochezia, and continuous postpartum bleeding in women:
Aconiti Lateralis Radix Praeparata (Wutou, 15 fen, processed, skin removed) Rheomi Radix et Rhizoma (Dahuang) Zingiberis Rhizoma (Ganjiang) Magnoliae Officinalis Cortex (Nongpu, roasted) Evodiae Fructus (Wuzhuyu) Paeoniae Radix (Shaoyao) Peucedani Radix (Qianhu) Chuanxiong Rhizoma (Chuanxiong) Angelicae Sinensis Radix (Danggui) Ginseng Radix (Renshen) Asteris Tatarici Radix (Ziwan) Glycyrrhizae Radix et Rhizoma (Gancao, roasted, each 1 liang)
The above eighteen ingredients are crushed, sifted into powder, mixed with refined honey to form pills the size of a wu zi. Take ten pills with wine, three times daily, gradually increasing the dose.
Formula mainly for wind-lao disease (chronic deficiency due to overwork) and cold from pin-masses (abdominal lumps) lasting forty years, and also for cough with rebellious qi:
Ginseng Radix (Renshen) Cinnamomi Ramulus (Guixin) Evodiae Fructus (Wuzhuyu) Aconiti Lateralis Radix Praeparata (Wutou, processed, skin removed) Alumen (Fanshi, burned, equal parts)
The above five ingredients are crushed, sifted into powder, mixed with refined honey to form pills the size of a wu zi. Take three pills with wine, twice daily, until effective.
Formula for treating toxic cold:
Alumen (Fanshi, burned) Platycodonis Radix (Jiegeng) Gleditsiae Sinensis Fructus (Zaojia, roasted, skin and seeds removed) Zingiberis Rhizoma (Ganjiang) Aconiti Radix Preparata (Fuzi, processed, skin removed) Evodiae Fructus (Wuzhuyu, equal parts)
The above six ingredients are crushed, sifted into powder, mixed with refined honey to form pills the size of a wu zi. Take three pills with water, twice daily. Gradually increase the dose until effective.
One treatise, thirty-five formulas connected with Volume 22.
Treatise says: Once the medicinal power is obtained, all ailments should be dispelled. If the medicinal power suddenly activates, one must know how to disperse it. Therefore, dispersal formulas are established next. Use them strictly according to diagnostic signs, and there will be no error. The pulse may be large (Hong) or excess (Shi), or interrupted and insufficient, resembling a death pulse; or fine and rapid (Xi Shu), or wiry and fast (Xian Kuai), because the diseases contracted are not uniform. Pulses have no constant pattern, and even doctors cannot always identify them. Heat predominance leads to wiry and fast pulses; presence of pin-masses leads to large and excess pulses; acute pain leads to interrupted pulses. Generally, when taking cold medicines that generate heat, this is usually the case. The patient feels no suffering, which is not a sign of death. If the reaction follows moderation, death will not occur. If it does not follow moderation, death will occur. Those who wish to take powder preparations should examine the pulse and carefully verify the signs before proceeding to complete recovery. A deep and rapid pulse is difficult to induce sweating; if difficult to sweat, purgation should be performed multiple times. A floating and large pulse is easy to induce sweating. Some people do not sweat after taking two or three doses of powder; this indicates their pulse is deep and difficult to mobilize. Sweating may occur without the person noticing, as the medicinal force has already moved internally. It does not manifest externally but acts internally within the body. To observe whether the medicinal power is working: increased food intake is the first sign; harmonious and pleasant complexion is the second sign; itching of the head, face, and body is the third sign; slight aversion to wind is the fourth sign; drowsiness is the fifth sign. For those presenting these signs, the medicine is activating the five zang organs internally. Simply follow the method of administration. Purge multiple times; internal deficiency will naturally lead to dispersion.