论曰∶《黄帝针经》曰，周痹者，在于血脉之中，随脉以上，随脉以下，不能左右，各
当其所。夫风寒湿之为痹，本痹而不通，今乃能周身上下者，以其邪中于血脉之间，与脉流
通，随气上下升降无碍也。故痛从上下者，先刺其下以遏之，后刺其上以脱之；痛从下上者
，先刺其上以遏之，后刺其下以脱之。刺法附于针灸门外，以药治之。
治周痹身体痿弱，不能行履。巴戟天散方。
巴戟天（去心半两） 芎 （一分） 附子（炮裂，去皮脐三分） 白蔹（一分） 黄
（炙，
锉） 桂（去粗皮） 细辛（去苗叶，炒各半两） 桔梗（炒一两） 人参（半两） 芍药
（一分）
牡丹实 天雄（炮裂，去皮脐各半两） 肉苁蓉（酒浸，切，焙一分） 萆 （炒半两） 赤
茯苓
（去黑皮） 牛膝（去苗，酒浸，切，焙各一两） 山芋 菊花（未开者，微炒） 秦艽（去
苗土
各半两） 乌喙（炮裂，去皮脐） 远志（去心各一两） 山茱萸 黄芩（去黑心） 白术
（微炒）
石斛（去根，锉） 白矾（研如粉各半两） 五味子（三分） 龙胆（去苗土） 蜀椒（去
目并闭
口，炒汗出各一分） 浓朴（去粗皮，生姜汁炙，锉半两） 菖蒲（九节者，去须节，先用
米泔
浸，后切，焙用一两）
上三十一味，除白矾别研外，将三十味捣罗为末，次入白矾末拌匀重罗。每服半钱匕，
渐加至一钱匕，温酒调下，日二夜一。未觉身唇口痹热，即渐加至一钱半匕。如觉大痹心烦
，以少许豉汤解之。
治周痹不仁。远志散方。
远志（去心） 黄 （炙，锉各半两） 芍药（一两） 五味子 黄芩（去黑心各一分）
赤
茯苓（去黑皮） 牡荆实（轻炒三分） 秦艽（去苗土一两） 乌头（炮裂，去皮脐） 天
雄（炮裂，
去皮脐） 细辛（去苗叶，微炒） 山茱萸 菊花（未开者，炒各半两） 防风（去叉三分）
狗
脊（去毛） 桂（去粗皮） 芎 芜荑（微炒各半两） 菖蒲（用米泔浸，去节、皮，焙）
葳蕤
（去土及须，焙各三分） 白蔹（生用） 山芋 附子（炮裂，去皮脐） 龙胆（去苗土） 浓
朴（去
粗皮，生姜汁炙，锉各半两） 蜀椒（去目并闭口，炒出汗） 巴戟天（去心各一分）
上二十七味，捣罗为散。每服一钱匕，空心温酒调下，渐加至二钱匕，日二夜一。
治周痹身体不仁。黄芩汤方。
黄芩（去黑心） 甘草（炙，锉） 防风（去叉各半两） 秦艽（去苗土） 葛根（锉）
杏仁（
去皮尖、双仁，麸炒各一分） 桂（去粗皮） 当归（切，焙） 赤茯苓（去黑皮各半两）
上九味，粗捣筛。每服六钱匕，以水酒各一盏，枣二枚（劈破），生姜一枣大（切），同
煎
至一盏，去滓温服，日二夜一。
治积年周痹，头发秃落，瘾胗生疮，气脉不通，搔之不觉痛痒。白术散方。
白术（微炒三两） 附子（炮裂，去皮脐二两） 石斛（去根，锉半两） 蜀椒（去目
并闭口
，炒出汗） 干姜（炮） 天雄（炮裂，去皮脐） 细辛（去苗叶，轻炒三分） 羊踯躅（微
炒半
两） 乌头（炮裂，去皮脐一两） 石南（用叶，洒醋微炒三分） 桂（去粗皮一两） 防
风（去
叉
上一十二味，捣罗为散。每服半钱至一钱匕，渐加至一钱半，温豆淋酒三合调下，空心
、临卧各一服。每服药后宜以少白羊脯嚼汁下药，续更用三合，温豆淋酒冲涤，更接药力，
常令有酒气。其药以韦皮袋贮，勿泄其气。初服身与 膝有汗。宜避外风。
治周痹脚胫细瘦，痿弱不能行立。金牙散方。
金牙（别研细一两） 防风（去叉） 侧子（炮裂，去皮脐） 当归（切，焙） 石膏
（别研细）
苗叶，轻炒） 黄芩（去黑心） 赤茯苓（去黑皮各一两半） 石南叶（洒酒炒） 人参（二
两）
上一十四味，除金牙、石膏别研外，将十二味捣罗为散，方入金牙、石膏末，拌匀重罗
。每服一钱半匕，渐加至二钱匕，空心温酒调下，日二夜一。未觉更增药至二钱半。
治周痹肢体脚膝无力。附子散方。
附子（炮裂，去皮脐） 狗脊（去毛各一分） 山芋 熟干地黄（焙） 王孙（去土，
生用）
桂（去粗皮） 天雄（炮裂，去皮脐） 山茱萸 秦艽（去苗土） 干漆（酒炒，令烟出） 防
风（去
叉） 甘草（炙各半两） 白蔹（一两）
上一十三味，捣罗为散。每服一钱匕，空心温酒调下，日二夜一，渐加至一钱半匕，服
之一月愈。
治周痹身体拘痛，腰膝痹 。六生散方。
生菖蒲（九节者，去毛、节，切，焙） 生干地黄（焙） 生枸杞根 生商陆根（净洗，
切
，焙各一斤） 生乌头（锉，去皮脐四两） 生姜（去皮，切，焙二斤）
上六味，先焙了各秤及本方分两，复以醇酒一斗五升，淹浸一宿，漉出曝干，复纳酒中，
令酒尽再曝干，捣罗为散。每服半钱匕，以清酒一盏调下，渐加至一钱匕，空心、临卧各一。
治八风十二痹。续命汤方。
羌活（去芦头三两） 茯神（去木） 薏苡仁（炒各一两）
上三味，粗捣筛。每服六钱匕，以水二盏，煎取一盏，别入竹沥一匙许，更煎数沸，去
滓温服，日二夜一。
治风湿周痹，肢节中痛，不可持物，行动无力，耳聋及肾脏虚损。益精髓，保神守中。
白石英浸酒方。
白石英（碎如大麻粒） 磁石（火 令赤，醋淬，如此五遍，捣各五两）
上二味，粗捣筛，生绢囊贮，以酒一升浸，经五六日。每服不计时，随性温服，服将尽
，可更添酒浸之。
治寒湿周痹。醍醐方。
醍醐一两
上一味。每日空心以温酒五合和一匙许服之。
治周痹。除五脏留滞，胃中结聚。益气止毒，润皮毛，补肾脏。大豆 方。
大豆 （一斤炒令香熟）
上一味，捣为末。每空腹温酒调下半匙，渐加至一匙。
治周痹。野驼脂方。
野驼脂（炼了滤过一斤）
上一味，别入好酥四两，同炼搅匀。每服半匙，以热酒半盏和化服之，渐加至一匙，空
心、食前各一。
Commentary states: The *Huangdi Zhenjing* (Yellow Emperor's Classic of Acupuncture) records that Zhou Bi (Generalized Bi Syndrome) resides within the blood vessels, moving upward along the meridians and downward along the meridians. It does not spread to the left or right but remains localized in its specific position. Although wind-cold-dampness pathogenic factors causing Bi syndrome typically result in local obstruction and blockage, when it affects the entire body from top to bottom, it is because the pathogen has invaded the space between the blood vessels, merging with the flow of qi and blood in the meridians, and circulating freely with the ascending and descending movement of qi without hindrance. Therefore, if pain develops from upper to lower, one should first needle the lower area to restrain the pathogen, then needle the upper area to expel it; if pain develops from lower to upper, one should first needle the upper area to restrain the pathogen, then needle the lower area to expel it. Specific needling methods are attached in the external section on acupuncture and moxibustion; here, only herbal treatment is described.
For treating Zhou Bi characterized by physical emaciation and weakness, inability to walk: Bajitian San Formula.
Morinda officinalis Radix (Bajitian) (remove woody core, 0.5 liang) Ligusticum chuanxiong Rhizoma (Chuanxiong) (1 fen) Aconitum carmichaelii Radix Preparata (Fuzi) (processed until cracked, remove skin and umbilical scar, 3 fen) Ampelopsis japonica Rhizoma (Bailian) (1 fen) Astragali Membranacei Radix (Huangqi) (stir-fried with honey, cut into pieces) Cinnamomi Ramulus (Guizhi) (remove rough bark) Asari Radix et Rhizoma (Xixin) (remove seedlings and leaves, stir-fried, 0.5 liang each) Platycodonis Radix (Jiegeng) (stir-fried, 1 liang) Ginseng Radix et Rhizoma (Renshen) (0.5 liang) Paeoniae Radix (Shaoyao) (1 fen) Moutan Cortex (Mudanpi/Mudanshi - text says Mudan shi, likely referring to root bark or fruit contextually treated similarly in some texts, but standard is Cortex) Paeoniae Radix Rubra? No, Mudan Pi is standard. Text says "Mudan Shi". Likely a typo for Mudan Pi or referring to seeds. Given context, usually Mudan Pi. Let's stick to text literal "Mudan fruit/shi" but note standard is Cortex. Actually, "Mudan Shi" might be a variant or error for Mudan Pi. I will translate as Moutan Cortex (Mudanpi). Aconitum kusnezoffii Radix (Tianxiong) (processed until cracked, remove skin and umbilical scar, 0.5 liang each) Cistanches Herba (Roucongrou) (soaked in wine, sliced, dried, 1 fen) Dioscoreae Hypoglaucae Rhizoma (Bixie) (stir-fried, 0.5 liang) Poria (Chifuling) (remove black skin) Cyathulae Radix (Niuxi) (remove seedlings, soaked in wine, sliced, dried, 1 liang each) Dioscorea opposita (Shanyu) Chrysanthemi Flos (Juahua) (unopened flowers, lightly stir-fried) Gentianae Macrophyllae Radix (Qinjiao) (remove seedlings and soil, 0.5 liang each) Aconitum Kusnezoffii Radix Lateralis Preparata (Wuhui) (processed until cracked, remove skin and umbilical scar) Polygalae Radix (Yuanzhi) (remove woody core, 1 liang each) Corni Fructus (Shanzhuyu) Scutellariae Radix (Huangqin) (remove black heart) Atractylodis Macrocephalae Rhizoma (Baizhu) (lightly stir-fried) Dendrobii Caulis (Shihu) (remove roots, cut into pieces) Alumen (Baifan) (ground into powder, 0.5 liang each) Schisandrae Chinensis Fructus (Wuweizi) (3 fen) Gentiana Scabra Radix et Rhizoma (Longdan) (remove seedlings and soil) Zanthoxyli Fructus (Shujiao) (remove eyes and closed mouths, stir-fried until sweat appears, 1 fen each) Magnoliae Officinalis Cortex (Houpo) (remove rough bark, stir-fried with ginger juice, cut into pieces, 0.5 liang) Acori Tatarinowii Rhizoma (Changpu) (nine-joint type, remove whiskers and nodes, soak in rice wash water first, then slice, dry, use 1 liang)
Thirty-one ingredients above. Except for Alumen which is ground separately, grind the other thirty ingredients into powder, sift, mix with Alumen powder evenly, and sift again. Take half qianbi per dose, gradually increase to one qianbi, take with warm wine, twice daily and once at night. If numbness, heat in lips and mouth is felt, gradually increase to one and a half qianbi. If severe Bi pain with irritability is felt, resolve with a small amount of Gardenia Tea (Douchi Tang).
For treating Zhou Bi characterized by insensitivity (numbness): Yuanzhi San Formula.
Polygalae Radix (Yuanzhi) (remove woody core) Astragali Membranacei Radix (Huangqi) (stir-fried with honey, cut into pieces, 0.5 liang each) Paeoniae Radix (Shaoyao) (1 liang) Schisandrae Chinensis Fructus (Wuweizi) Scutellariae Radix (Huangqin) (remove black heart, 1 fen each) Poria (Chifuling) (remove black skin) Viticis Fructus (Mujingshi) (lightly stir-fried, 3 fen) Gentianae Macrophyllae Radix (Qinjiao) (remove seedlings and soil, 1 liang) Aconiti Radix (Wutou) (processed until cracked, remove skin and umbilical scar) Aconitum Kusnezoffii Radix Lateralis Preparata (Tianxiong) (processed until cracked, remove skin and umbilical scar) Asari Radix et Rhizoma (Xixin) (remove seedlings and leaves, lightly stir-fried) Corni Fructus (Shanzhuyu) Chrysanthemi Flos (Juahua) (unopened flowers, stir-fried, 0.5 liang each) Saposhnikoviae Radix (Fangfeng) (remove forked branches, 3 fen) Cibotii Rhizoma (Gouji) (remove hair) Cinnamomi Ramulus (Guizhi) (remove rough bark) Ligusticum chuanxiong Rhizoma (Chuanxiong) Elaeagnoides Fructus (Wuyi) (lightly stir-fried, 0.5 liang each) Acori Tatarinowii Rhizoma (Changpu) (soak in rice wash water, remove nodes and skin, dry) Polygonati Reticulati Rhizoma (Weirui/Yuzhu) (remove soil and whiskers, dry, 3 fen each) Ampelopsis japonica Rhizoma (Bailian) (use raw) Dioscorea opposita (Shanyu) Aconitum carmichaelii Radix Preparata (Fuzi) (processed until cracked, remove skin and umbilical scar) Gentiana Scabra Radix et Rhizoma (Longdan) (remove seedlings and soil) Magnoliae Officinalis Cortex (Houpo) (remove rough bark, stir-fried with ginger juice, cut into pieces, 0.5 liang each) Zanthoxyli Fructus (Shujiao) (remove eyes and closed mouths, stir-fried until sweat appears) Morinda officinalis Radix (Bajitian) (remove woody core, 1 fen each)
Twenty-seven ingredients above. Grind into powder, sift. Take one qianbi per dose, take with warm wine on an empty stomach, gradually increase to two qianbi, twice daily and once at night.
For treating Zhou Bi characterized by physical insensitivity: Huangqin Tang Formula.
Scutellariae Radix (Huangqin) (remove black heart) Glycyrrhizae Radix et Rhizoma (Gancao) (stir-fried with honey, cut into pieces) Saposhnikoviae Radix (Fangfeng) (remove forked branches, 0.5 liang each) Gentianae Macrophyllae Radix (Qinjiao) (remove seedlings and soil) Puerariae Lobatae Radix (Gegen) (cut into pieces) Armeniacae Semen Amarum (Xingren) (remove skin and tips, non-double kernels, stir-fried with bran, 1 fen each) Cinnamomi Ramulus (Guizhi) (remove rough bark) Angelicae Sinensis Radix (Danggui) (slice, dry) Poria (Chifuling) (remove black skin, 0.5 liang each)
Nine ingredients above. Coarsely crush and sieve. Take six qianbi per dose, with one cup of water and one cup of wine, two Jujubes (split), and one piece of Ginger (size of a jujube, sliced). Decoct together to one cup, remove dregs, take warm, twice daily and once at night.
For treating chronic Zhou Bi with hair loss, urticaria and sores, blocked qi and vessels, and lack of sensation to itching or pain upon scratching: Baizhu San Formula.
Atractylodis Macrocephalae Rhizoma (Baizhu) (lightly stir-fried, 3 liang) Aconitum carmichaelii Radix Preparata (Fuzi) (processed until cracked, remove skin and umbilical scar, 2 liang) Dendrobii Caulis (Shihu) (remove roots, cut into pieces, 0.5 liang) Zanthoxyli Fructus (Shujiao) (remove eyes and closed mouths, stir-fried until sweat appears) Zingiberis Rhizoma Recens (Ganjiang/Dried Ginger) (processed) Aconitum Kusnezoffii Radix Lateralis Preparata (Tianxiong) (processed until cracked, remove skin and umbilical scar) Asari Radix et Rhizoma (Xixin) (remove seedlings and leaves, lightly stir-fried, 3 fen) Daphne Genkwa Flos (Yangzhizhu) (lightly stir-fried, 0.5 liang) Aconiti Radix (Wutou) (processed until cracked, remove skin and umbilical scar, 1 liang) Nandinae Folium (Shinan) (use leaves, sprinkle with vinegar, lightly stir-fried, 3 fen) Cinnamomi Ramulus (Guizhi) (remove rough bark, 1 liang) Saposhnikoviae Radix (Fangfeng) (remove forked branches)
Twelve ingredients above. Grind into powder, sift. Take half to one qianbi per dose, gradually increase to one and a half qianbi, take with three he of warm Doulin Wine (wine infused with soybeans), on an empty stomach and before bed. After taking the medicine, chew a small amount of white mutton jerky for juice to swallow the medicine, then follow with three he of warm Doulin Wine to flush the system and enhance medicinal power, maintaining a sensation of alcohol in the body. Store medicines in leather bags to prevent gas leakage. Initially, sweating may occur on the body and knees. Avoid external wind.
For treating Zhou Bi with thin and emaciated calves, emaciation and weakness preventing standing and walking: Jinya San Formula.
Gold Tooth (Jinya - likely a mineral or specific herb name, possibly Jin Qian Cao or similar, but literally "Gold Tooth") (grind finely separately, 1 liang) Saposhnikoviae Radix (Fangfeng) (remove forked branches) Aconiti Lateralis Radix Preparata (Cezi) (processed until cracked, remove skin and umbilical scar) Angelicae Sinensis Radix (Danggui) (slice, dry) Gypsum Fibrosum (Shigao) (grind finely separately) [Missing Herb Name] (remove seedlings and leaves, lightly stir-fried) Scutellariae Radix (Huangqin) (remove black heart) Poria (Chifuling) (remove black skin, 1.5 liang each) Nandinae Folium (Shinan Ye) (sprinkle with wine, stir-fried) Ginseng Radix et Rhizoma (Renshen) (2 liang)
Fourteen ingredients above. Except for Jinya and Shigao which are ground separately, grind the other twelve ingredients into powder, add Jinya and Shigao powders, mix evenly, and sift. Take one and a half qianbi per dose, gradually increase to two qianbi, take with warm wine on an empty stomach, twice daily and once at night. If ineffective, increase dosage to two and a half qianbi.
For treating Zhou Bi with weakness in limbs, feet, and knees: Fuzi San Formula.
Aconitum carmichaelii Radix Preparata (Fuzi) (processed until cracked, remove skin and umbilical scar) Cibotii Rhizoma (Gouji) (remove hair, 1 fen each) Dioscorea opposita (Shanyu) Prepared Rehmanniae Radix (Shugadihuang) (dry) Pseudostellariae Radix (Wangsun) (remove soil, use raw) Cinnamomi Ramulus (Guizhi) (remove rough bark) Aconitum Kusnezoffii Radix Lateralis Preparata (Tianxiong) (processed until cracked, remove skin and umbilical scar) Corni Fructus (Shanzhuyu) Gentianae Macrophyllae Radix (Qinjiao) (remove seedlings and soil) Drynariae Rhizoma? No, Ganqi (Dry Lacquer) (stir-fried with wine until smoke appears) Saposhnikoviae Radix (Fangfeng) (remove forked branches) Glycyrrhizae Radix et Rhizoma (Gancao) (stir-fried with honey, 0.5 liang each) Ampelopsis japonica Rhizoma (Bailian) (1 liang)
Thirteen ingredients above. Grind into powder, sift. Take one qianbi per dose, take with warm wine on an empty stomach, twice daily and once at night, gradually increase to one and a half qianbi. Cure after one month of administration.
For treating Zhou Bi with stiff and painful body, and Bi pain in waist and knees: Liusheng San Formula.
Raw Acori Tatarinowii Rhizoma (Sheng Changpu) (nine-joint type, remove hair and nodes, slice, dry) Raw Prepared Rehmanniae Radix (Sheng Gan Dihuang - likely means fresh Rehmannia processed/dried) Raw Lycii Cortex (Sheng Gouqigen) Raw Phytolaccae Radix (Sheng Shanglugen) (cleanly washed, sliced, dry, 1 jin each) Raw Aconiti Radix (Sheng Wutou) (cut into pieces, remove skin and umbilical scar, 4 liang) Raw Zingiberis Rhizoma (Sheng Jiang) (remove skin, slice, dry, 2 jin)
Six ingredients above. First dry them, weigh according to the formula, then soak in 1.5 dou of strong wine overnight. Strain out and dry in the sun, put back into the wine, let the wine be absorbed, then dry again. Grind into powder, sift. Take half qianbi per dose, take with one cup of clear wine, gradually increase to one qianbi, on an empty stomach and before bed.
For treating Eight Winds and Twelve Bis: Xuming Tang Formula.
Notopterygii Radix et Rhizoma (Qianghuo) (remove rhizome head, 3 liang) Poria Cum Pinodia (Fushen) (remove wood) Coicis Semen (Yiyiren) (stir-fried, 1 liang each)
Three ingredients above. Coarsely crush and sieve. Take six qianbi per dose, with two cups of water, decoct to one cup. Add one spoonful of Bamboo Sap (Zhuli), boil a few more times, remove dregs, take warm, twice daily and once at night.
For treating Wind-Damp Zhou Bi with joint pain, inability to hold objects, weakness in movement, deafness, and Kidney deficiency. To benefit essence and marrow, preserve spirit and center. Bai Shiyinqing Jiu Formula.
Quartz (Bai Shiyin) (crushed like hemp seeds) Magnetitum (Cishi) (fire until red, quench in vinegar, repeat five times, grind, 5 liang each)
Two ingredients above. Coarsely crush and sieve, store in a raw silk bag, soak in one sheng of wine for five to six days. Take warm at any time as desired. When nearly finished, add more wine to soak.
For treating Cold-Damp Zhou Bi: Tituhu Formula.
Tituhu (Clarified Butter/Ghee) (1 liang)
One ingredient above. Take one spoonful mixed with five he of warm wine on an empty stomach daily.
For treating Zhou Bi. Remove stagnation in Five Zang, resolve accumulations in Stomach. Benefit Qi, stop toxins, moisten skin and hair, tonify Kidneys. Da Dou [Zhi/Gao] Formula.
Soybean [Fat/Paste] (Da Dou Zhi/Gao) (1 jin, stir-fried until fragrant and cooked)
One ingredient above. Grind into powder. Take half a spoonful mixed with warm wine on an empty stomach, gradually increase to one spoonful.
For treating Zhou Bi: Wild Camel Fat Formula.
Wild Camel Fat (Ye Tuo Zhi) (refined and filtered, 1 jin)
One ingredient above. Mix with four liang of good clarified butter (Su), refine and stir evenly. Take half a spoonful, dissolve in half a cup of hot wine, gradually increase to one spoonful, on an empty stomach and before meals.