论曰疟痢者，疟久不瘥，寒热邪气内传肠胃也。其病寒热往来，利下脓血，赤白相杂，
肠中切痛，随其阴阳而治之。
治疟兼痢，无问赤白，水谷鲜血，皆主之。黄连犀角丸方
黄连（去须） 犀角屑 豉（炒各二两） 龙骨（四两） 牡蛎（熬半两）
上五味。为细末，炼蜜丸如梧桐子大，每服三十丸，米饮下，日三。
治疟痢无度，赤白相杂。黄连丸方
黄连（去须） 黄柏（去粗皮锉炒） 羚羊角屑 艾叶（炒） 赤芍药（各二两） 当
归（切焙一两）
上六味。为细末，炼蜜和捣三百杵，丸如梧桐子大。每服三十丸，粥饮下，不拘时。
治疟痢挟热，下血腹痛。地榆汤方
地榆（锉） 黄连（去须） 黄芩（去黑心） 犀角屑（各一两） 升麻 茜根（各半
两）
上六味。粗捣筛，每服四钱匕，水一盏半，煎至八分，去滓温服，不拘时。
治疟兼痢不止。常山丸方
常山 黄连（去须） 豉（炒各三两） 附子（炮裂去皮脐二两）
上四味。为细末，炼蜜丸梧桐子大，每服四丸，米饮下，未发前空腹服，欲发更服三丸
，自旦至暮乃食，三日勿杂食佳。
治疟痢苦渴。乌梅饮方
乌梅（二十枚劈破）
上一味。以水三盏，煎至一盏，去滓和蜜一匙，细细饮之。
治疟痢。黄连散方
黄连（去须） 当归（切焙各一两） 干姜（炮半两）
上三味。为细散，每服三钱匕，水一盏，煎至七分，放温临发时服，如茶点，或热水调
服亦得。
治疟痢。牡蛎散方
牡蛎（熬） 常山（锉） 陈橘皮（汤浸去白焙） 桂（去粗皮各三分）
上四味。为细散，每服一钱匕，温酒调下。
治疟气急黄并痢。前胡丸方
前胡（去芦头） 赤茯苓（去黑皮） 芍药 枳壳（去瓤麸炒） 黄芩（去黑心各半两）
大黄（一两生）
上七味。为细末，炼蜜丸如梧桐子大，每服十丸，午食前，以米饮及浆水下，令溏利为
度，不利加至十五丸，老小量意服之，有 癖者，宜加后药。
虻虫（去翅足炒二十枚） 黄 （薄切） 天门冬（去心焙各一两） 鳖甲（去裙 醋
炙） 生干地黄（焙各二两） 赤茯苓（去黑皮） 人参（各半两）
上七味。为细末，与前药末相和，炼蜜丸如梧桐子大，每服二十丸，渐加至三十丸，空
心地黄酒下，以瘥为度。
It is stated that malaria-dysentery (Malari-Dysenteria) refers to a condition where malaria persists for a long time without healing, and the pathogenic factors of cold and heat transmit internally into the intestines and stomach. The disease manifests with alternating chills and fever, diarrhea discharging pus and blood, with red and white colors mixed, and severe cutting pain in the intestines. Treatment should be conducted according to the yin and yang nature of the syndrome.
For treating malaria accompanied by dysentery, regardless of whether the stool is red or white, watery, containing undigested food, or bloody, this formula is indicated. Coptis Rhizome and Rhinoceros Horn Pill Formula (Huanglian Xijiao Wan):
Coptis Rhizome (Huoxie, 黄连) (remove roots), Rhinoceros Horn (Xijiao, 犀角), Fermented Soybean (Chixiang, 豆豉) (stir-fried), each 2 liang; Dragon Bone (Longgu, 龙骨) 4 liang; Oyster Shell (Muli, 牡蛎) (calcined) 0.5 liang.
The above five ingredients are ground into fine powder, mixed with refined honey to form pills the size of Sophora japonica seeds. Take 30 pills per dose, administered with rice water, three times daily.
For treating unremitting malaria-dysentery with mixed red and white stools. Coptis Rhizome Pill Formula (Huanglian Wan):
Coptis Rhizome (Huoxie, 黄连) (remove roots), Phellodendron Bark (Huangbai, 黄柏) (remove coarse bark, cut, stir-fried), Antelope Horn (Lingyangjiao, 羚羊角), Mugwort Leaf (Aiye, 艾叶) (stir-fried), Red Peony Root (Chishao, 赤芍药), each 2 liang; Angelica Sinensis Radix (Danggui, 当归) (cut and baked) 1 liang.
The above six ingredients are ground into fine powder, kneaded with refined honey and pounded three hundred times, then formed into pills the size of Sophora japonica seeds. Take 30 pills per dose, administered with porridge water, at any time.
For treating malaria complicated by heat, with hematochezia and abdominal pain. Sanguisorba Decoction (Diyu Tang):
Sanguisorba Radix (Diyu, 地榆) (cut), Coptis Rhizome (Huoxie, 黄连) (remove roots), Scutellaria Root (Huangqin, 黄芩) (remove black heart), Rhinoceros Horn (Xijiao, 犀角), each 1 liang; Cimicifuga Rhizome (Shengma, 升麻), Rubia Root (Qiancao, 茜根), each 0.5 liang.
The above six ingredients are coarsely crushed and sieved. Take four qianbi (approx. 4-6g) per dose, add one and a half zhan (approx. 300ml) of water, decoct until eight-tenths remain, strain, and take warm at any time.
For treating malaria accompanied by persistent dysentery. Dichroa Pill Formula (Changshan Wan):
Dichroa Radix (Changshan, 常山), Coptis Rhizome (Huoxie, 黄连) (remove roots), Fermented Soybean (Chixiang, 豆豉) (stir-fried), each 3 liang; Aconite Lateralis Radix Preparata (Fuzi, 附子) (processed, cracked, peel and umbilicus removed) 2 liang.
The above four ingredients are ground into fine powder, mixed with refined honey to form pills the size of Sophora japonica seeds. Take 4 pills per dose, administered with rice water. Take on an empty stomach before the attack; if an attack is imminent, take 3 more pills. Eat only from morning to evening. It is advisable to avoid mixed foods for three days.
For treating malaria-dysentery causing severe thirst. Mume Infusion (Wumei Yin):
Mume Fructus (Wumei, 乌梅) (20 fruits, split).
The above single ingredient is decocted in three zhan (approx. 600ml) of water until one zhan remains. Strain, mix with one spoonful of honey, and drink slowly.
For treating malaria-dysentery. Coptis Rhizome Powder (Huanglian San):
Coptis Rhizome (Huoxie, 黄连) (remove roots), Angelica Sinensis Radix (Danggui, 当归) (cut and baked), each 1 liang; Dried Ginger (Ganjiang, 干姜) (processed) 0.5 liang.
The above three ingredients are ground into fine powder. Take three qianbi per dose, add one zhan of water, decoct until seven-tenths remain, let cool to warm, and take at the time of onset. It can be taken like tea infusion, or mixed with hot water.
For treating malaria-dysentery. Oyster Shell Powder (Muli San):
Oyster Shell (Muli, 牡蛎) (calcined), Dichroa Radix (Changshan, 常山) (cut), Tangerine Peel (Chenpi, 陈橘皮) (soaked in hot water, white pith removed, baked), Cinnamon Twig (Guizhi, 桂) (remove coarse bark), each 3 fen.
The above four ingredients are ground into fine powder. Take one qianbi per dose, mixed with warm wine.
For treating malaria qi with acute jaundice and dysentery. Peucedani Radix Pill Formula (Qianhu Wan):
Peucedani Radix (Qianhu, 前胡) (remove rhizome head), Red Poria (Chifuling, 赤茯苓) (remove black skin), Peony Root (Shaoyao, 芍药), Aurantium Fructus (Zhike, 枳壳) (remove pulp, bran-fried), Scutellaria Root (Huangqin, 黄芩) (remove black heart), each 0.5 liang; Rheum Palmatum Radix et Rhizoma (Dahuang, 大黄) (raw) 1 liang.
The above seven ingredients are ground into fine powder, mixed with refined honey to form pills the size of Sophora japonica seeds. Take 10 pills per dose, before noon meal, administered with rice water and fermented grain liquid. The goal is loose stool; if no loose stool occurs, increase to 15 pills. Dosage for elderly and children should be adjusted accordingly. For those with masses (zheng ji), add the following herbs:
Tabanus Insect (Mengchong, 虻虫) (remove wings and feet, stir-fried) 20 insects; Astragalus Membranaceus Radix (Huangqi, 黄芪) (thin slices), Asparagus Cochinchinensis Rhizome (Tianmendong, 天门冬) (remove heart, bake), each 1 liang; Turtle Carapax (Biejia, 鳖甲) (remove skirt, vinegar-fried); Raw Dried Rehmannia Root (Shengdihuang, 生干地黄) (bake) 2 liang; Red Poria (Chifuling, 赤茯苓) (remove black skin), Ginseng Radix et Rhizoma (Renshen, 人参), each 0.5 liang.
The above seven ingredients are ground into fine powder and mixed with the previous powder. Mix with refined honey to form pills the size of Sophora japonica seeds. Take 20 pills per dose, gradually increasing to 30 pills, administered with yellow wine on an empty stomach, until recovery.