治大下后虚劳不得眠，剧者颠倒懊恼欲死方。（仲景云，发汗吐下后，虚烦不得眠，若
剧者必反复颠倒，心中懊恼，栀子汤主之。）
大栀子（十四枚） 豉（七合）
上二味，以水四升先煮栀子取二升半，纳豉更煮三沸，去滓。每服一升，安者勿更服。
若上气呕逆，加橘皮二两，亦可加生姜二两。
治烦闷不得眠方∶ 枸杞白皮、生地黄（各五两） 麦门冬 甘草 前胡（各五两） 茯
苓
上十味 咀，以水八升煮取三升七合，分四服。
治虚劳不得眠方∶
酸枣仁 榆叶（等分）
上二味为末，蜜丸如梧桐子大，每服十五丸，日再。
又方 干姜四两为末，汤和顿服，覆取汗愈。
胆实热灸浊浴，随年壮，穴在挟胆俞旁相行去五寸。
胆虚灸三阴交各二十壮，穴在内踝上一夫。
（论一首）
论曰∶夫咽门者，应五脏六腑往来神气阴阳通塞之道也。喉咙包囊舌者，并津液调五味
之气本也，不可不研乎。咽门者，肝胆之候也，主通五脏六腑津液神气应十二时。若脏热则
咽门闭而气塞，若腑寒则咽门破而声嘶，母姜酒主之。（方见六卷喉病门。）热则通之，寒则
补之，若寒热调和，病不生矣。
（论一首，方二首）
论曰∶髓虚者，脑痛不安，实者勇悍。凡髓虚实之应主于肝胆。若其腑脏有病，病从髓
生，热则应脏，寒则应腑。
To treat deficiency exhaustion and insomnia following severe purgation, where in severe cases the patient experiences restlessness, tossing and turning, and profound mental distress bordering on death. (Zhang Zhongjing stated: After sweating, vomiting, or purging, if there is empty irritability and inability to sleep, and in severe cases, repeated tossing and turning with profound mental distress, Zhi Zi Tang [Gardenia Decoction] should be used.)
Da Zhi Zi (Gardeniae Fructus) (14 pieces) Chi (Fermented Soybean) (7 he)
Take the above two ingredients, add four sheng of water, first decoct Da Zhi Zi until two and a half sheng remain, then add Chi and boil for three boils. Strain the dregs. Take one sheng per dose. If sleep is restored, do not take further doses.
If there is rebellious Qi and vomiting, add Ju Pi (Citri Reticulatae Pericarpium) 2 liang; alternatively, add Sheng Jiang (Zingiberis Rhizoma Recens) 2 liang.
To treat irritability and insomnia: Gou Qi Bai Pi (Lycii Cortex) and Sheng Di Huang (Rehmanniae Radix) (each 5 liang), Mai Men Dong (Ophiopogonis Tuber), Gan Cao (Glycyrrhizae Radix et Rhizoma), Qian Hu (Peucedani Radix) (each 5 liang), Fu Ling (Poria).
Take the above ten ingredients, cut into small pieces, add eight sheng of water, decoct to obtain three sheng and seven he, divide into four doses.
To treat deficiency exhaustion and insomnia: Suan Zao Ren (Ziziphi Spinosae Semen) and Yu Ye (Ulmus Folium) (equal parts).
Grind the above two ingredients into powder, make pills with honey the size of Sophora japonica seeds. Take fifteen pills per dose, twice daily.
Another prescription: Gan Jiang (Zingiberis Rhizoma) 4 liang ground into powder, mixed with boiling water and taken in one dose. Cover with blankets to induce sweating for cure.
For Gallbladder Excess-Heat, moxa Zhuo Yu [acupoint], number of moxa cones according to age. The acupoint is located five cun lateral to Dan Shu [BL-19].
For Gallbladder Deficiency, moxa San Yin Jiao [SP-6], twenty cones per acupoint. The acupoint is located one fu above the medial malleolus.
(One Treatise)
The treatise states: The pharyngeal gate is the pathway through which the divine Qi and Yin-Yang of the Five Zang and Six Fu organs circulate, determining their patency or obstruction. The throat envelops the tongue and is the root of fluids harmonizing the qi of the five flavors; this must be studied carefully. The pharyngeal gate is the external manifestation of the Liver and Gallbladder, governing the circulation of fluids and divine Qi of the Five Zang and Six Fu organs, corresponding to the twelve double-hours. If the Zang organs are hot, the pharyngeal gate closes and Qi becomes obstructed; if the Fu organs are cold, the pharyngeal gate ruptures and the voice becomes hoarse. Mu Jiang Jiu [Mother Ginger Wine] is used to treat this. (See Formula in Volume 6, Throat Diseases Section.) Heat is treated by promoting flow; Cold is treated by tonification. If Cold and Heat are harmonized, disease will not arise.
(One Treatise, Two Formulas)
The treatise states: In Marrow Deficiency, there is headache and restlessness; in Marrow Excess, there is courage and ferocity. Generally, the deficiency or excess of Marrow is governed by the Liver and Gallbladder. If the Zang and Fu organs have disease, the disease arises from the Marrow; Heat corresponds to the Zang, and Cold corresponds to the Fu.