病源此由邪气与卫气俱行于六腑，而有时相失不相得，故邪气内搏五脏，则道远气深，
故其行迟，不能与卫气偕出，是以间日而作也。（出第十一卷中）
备急疗间日疟方。
烧黑牛尾作灰，酒服方寸匕，日三服。（出第十卷中）
又桂广州法醇 汤方。
大黄（三分） 甘草（一分半炙） 常山（一分半）
上三味，以水三升，煮取一升，去滓，更以水二升煮滓取一升，未发服 是后煮者，
相次服醇，醇是前煮者瘥。忌菘菜海藻生葱生菜等。（支云极验文仲经心录方无甘草用石膏
三铢余同一方有桂心一分半出第二卷中）
病源夫疟皆由伤暑及伤风所为，热盛之时，发汗吐下过度，腑脏空虚营卫伤损，邪气伏
藏所以引日不瘥，仍故休作也，疟岁岁发，至三岁发连日发不解，胁下有痞，疗之不得攻其
痞，但得虚其津液，先其时发其汗，服汤已，先寒引衣自覆汗出，小便自利，则愈也。（出
第十一卷中）
深师疗久疟难断香豉丸方。
香豉（一分熬） 常山（七分） 蜀漆（十分） 附子（一分炮） 大黄（二分好者）
上五味捣下筛，蜜和，发日早服五丸如梧子，须臾又服五丸，发晚者，至发可三四服，
令其得吐为佳，欲不即断畏吐者，但则长将久服，无不瘥也。忌生葱生菜猪肉。
又疗三十年疟，常山汤方。
常山（三两） 黄连（三两）
上二味切，以酒一斗宿渍之，向晚以瓦釜煮取六升，一服八合，比发时，令得三服，有
热当吐，有冷当下，服之者千百无一不断，亦可半合，无服全剂者。忌猪肉冷水生葱生菜。
（并出
千金栀子汤，主疟经数年不瘥者，两剂瘥，一月以来一剂瘥方。
栀子（十四枚） 常山（三两） 车前叶（二十枚炙干） 秫米（十四粒）
上四味切，以水九升，煮取三升，分三服，未发一服，发时一服，发后一服，以吐利四
五行为瘥，不止，冷冻饮料止之。忌生葱生菜。（出第十卷中）
崔氏疗疟，纵久患者不过五六服以来亦瘥。常山散方。
常山（三两） 干漆（三两熬烟尽） 牡蛎（一两半熬） 桂心（三两） 橘皮（二两）
杏仁（
二两去皮尖熬）
上六味捣筛为散，一服方寸匕，先发热，饮和服，若先寒清酒和服之，时取未发前一食
顷服，服药日唯须晚食，七日内慎如药法。忌生葱生菜。（出第四卷中）
备急龙骨丸，疗久疟不断者方。
龙骨（一两） 常山（三两） 大黄（二两） 附子（二分炮）
上四味捣末，以鸡子黄丸如梧子大，先发临发，各饮服五丸，无不断，长将服之，支云
神验，疗三十年疟。忌生葱生菜猪肉等。（张文仲支方同出第二卷中）
备急疗疟连绵积日不瘥，常山散方。
常山（三两） 羚羊角（三两炙令焦） 乌梅肉（三两） 黄芩（二两） 甘草（一两
半炙）
上五味捣为散，以竹叶煮饮取六七合，饮及热用，调常山散三方寸匕，未发前一服，若
瘥停，不瘥临欲发，又进二寸匕，老小以意量之。忌海藻菘菜生葱生菜。
又疗疟无问年月远近并瘥，乌梅丸方。
乌梅肉（三两熬） 苁蓉（三两） 桃仁（三两熬去皮） 常山（三两熬） 升麻（二
两炙）
桂心（二两） 甘草（二两炙）
上七味捣筛，蜜和丸如梧子大，未发时酒服二十丸欲至发时更服二十丸，百无所忌，唯
触之则难瘥，饮服亦得，此药或吐利，或不吐利，勿 ，五六日频进佳。忌海藻菘菜生葱生
菜。（一方有豉三两熬文仲备急同并出第一卷中）
近效疗久难瘥疟，常山酒方。
常山（三两） 鳖甲（二两炙） 鲮鲤甲（一两炙） 乌贼鱼骨（一两炙） 乌梅肉（七
枚） 桃
仁（四十九枚去皮尖别捣如泥） 竹叶（切一升） 豉（三合熬令香） 葱白（切一升）
上九味细切，合以酒三升渍经再宿，空腹早朝温服一合，良久取吐，如不吐，至齐午以
来服之，四服如不瘥，隔日更依前服必瘥，瘥后十日内，不得吃冷水粘滑人苋生菜，余如常。
（
Pathogenesis: This occurs because pathogenic factors and Wei Qi (Defensive Qi) travel together through the Six Fu Organs, but sometimes lose coordination and fail to synchronize. Consequently, pathogenic factors press inward against the Five Zang Organs, resulting in a distant disease location and deep-seated Qi dynamics. Thus, the movement of pathogens is slow, preventing them from exiting simultaneously with Wei Qi, which is why the malaria attacks every other day. (From Volume XI)
Emergency Prescription for Intermittent Malaria.
Burn black ox tail into ash, take one Fang Cun Bi (a square-inch measure) with wine, three times daily. (From Volume X)
Another method from Guangzhou, Chun Decoction.
Da Huang (Rhubarb Root and Rhizome, 3 fen), Gan Cao (Licorice Root, 1.5 fen, honey-fried), Chang Shan (Dichroa Root, 1.5 fen).
Crush the above three ingredients. Boil in 3 sheng of water to obtain 1 sheng of decoction, then strain. Add 2 sheng of water to the dregs and boil again to obtain 1 sheng. Take the first decoction before the onset of fever. Subsequently, take the second decoction in succession. "Chun" refers to the first decoction; if cured after taking it, stop. Avoid eating Song Cai (Chinese Cabbage), Hai Zao (Seaweed), raw Cong (Scallion), and raw vegetables. (Zhi claimed this method was extremely effective. Wen Zhong's Jing Xin Lu prescription omits Gan Cao and uses Shi Gao [Gypsum] 3 zhu instead, otherwise identical. Another version includes Gui Xin [Cinnamon Twig Heart] 1.5 fen, from Volume II.)
Pathogenesis: Malaria is caused by damage from Summerheat and Wind-Cold. During periods of intense heat, excessive sweating, vomiting, or purging can lead to emptiness in the Zang-Fu organs and damage to Ying Qi (Nutritive Qi) and Wei Qi (Defensive Qi). Pathogenic factors lie dormant, causing prolonged illness without resolution, yet still recurring at intervals. If malaria recurs annually for three years or more, or continues daily without relief, and there is a mass under the hypochondrium, treatment should not directly attack the mass. Instead, one should deplete the body fluids slightly and induce sweating before the onset. After taking the decoction, the patient will initially feel cold and cover themselves with clothes. Once sweat appears and urination becomes normal, the disease will be cured. (From Volume XI)
Shen Shi Prescription for Stubborn Chronic Malaria, Xiang Chi Pill.
Xiang Chi (Fermented Soybean, 1 fen, roasted), Chang Shan (Dichroa Root, 7 fen), Shu Qi (Radix Dichroae Preparata, 10 fen), Fu Zi (Prepared Aconite Root, 1 fen, processed), Da Huang (Rhubarb Root and Rhizome, 2 fen, high quality).
Grind the above five ingredients into powder and sift. Mix with honey to form pills the size of wu zi (wu-tzu seeds). On the day of onset, take five pills early in the morning, and another five pills shortly after. If the onset is late, take three to four doses before the onset. Inducing vomiting is ideal. For those who fear vomiting but wish to cure it quickly, long-term slow administration will ensure recovery. Avoid raw Cong (Scallion), raw vegetables, and pork.
Another Prescription for Thirty-Year Malaria, Chang Shan Decoction.
Chang Shan (Dichroa Root, 3 liang), Huang Lian (Coptis Rhizome, 3 liang).
Cut the above two ingredients. Soak in one dou of wine overnight. In the evening, boil in a clay pot to obtain six sheng. Take eight he per dose. Before the onset, ensure three doses are taken. Heat symptoms may cause vomiting; cold symptoms may cause diarrhea. Among thousands who take this, almost none remain uncured. Dosage may be halved; full dosage is rarely used. Avoid pork, cold water, raw Cong (Scallion), and raw vegetables.
(All from... Qian Jin Zhi Zi Decoction, mainly for malaria persisting for years, cured in two doses; or cured in one dose within a month.)
Zhi Zi (Gardenia Fruit, 14 pieces), Chang Shan (Dichroa Root, 3 liang), Che Qian Ye (Plantago Leaf, 20 pieces, dried by roasting), Shu Mi (Millet, 14 grains).
Cut the above four ingredients. Boil in nine sheng of water to obtain three sheng. Divide into three doses: one before onset, one during onset, and one after onset. Recovery is indicated by four to five episodes of vomiting or diarrhea. If these do not cease, use frozen drinks to stop them. Avoid raw Cong (Scallion) and raw vegetables. (From Volume X)
Cui Shi’s Method for Malaria: Even in chronic cases, recovery usually occurs within five to six doses. Chang Shan Powder.
Chang Shan (Dichroa Root, 3 liang), Gan Xi (Dried Lacquer, 3 liang, roasted until smoke ceases), Mu Li (Oyster Shell, 1.5 liang, calcined), Gui Xin (Cinnamon Twig Heart, 3 liang), Ju Pi (Tangerine Peel, 2 liang), Xing Ren (Apricot Seed, 2 liang, skin and tip removed, roasted).
Grind the above six ingredients into powder. Take one Fang Cun Bi per dose. If fever precedes chills, mix with warm water; if chills precede fever, mix with clear wine. Take approximately one meal time before the onset of fever. On the day of medication, only eat dinner. Observe dietary restrictions strictly for seven days. Avoid raw Cong (Scallion) and raw vegetables. (From Volume IV)
Emergency Long Gu Pill, for Persistent Chronic Malaria.
Long Gu (Fossilized Bone, 1 liang), Chang Shan (Dichroa Root, 3 liang), Da Huang (Rhubarb Root and Rhizome, 2 liang), Fu Zi (Prepared Aconite Root, 2 fen, processed).
Grind the above four ingredients into powder. Mix with egg yolk to form pills the size of wu zi (wu-tzu seeds). Take five pills with water just before and just at the onset of fever. All cases are cured. Long-term use is recommended. Zhi claimed this is miraculous for thirty-year malaria. Avoid raw Cong (Scallion), raw vegetables, and pork. (Zhang Wen Zhong and Zhi prescriptions are identical, from Volume II.)
Emergency Prescription for Continuous Malaria Persisting for Days, Chang Shan Powder.
Chang Shan (Dichroa Root, 3 liang), Ling Yang Jiao (Antelope Horn, 3 liang, roasted until scorched), Wu Mei (Mume Fruit Flesh, 3 liang), Huang Qin (Scutellaria Root, 2 liang), Gan Cao (Licorice Root, 1.5 liang, honey-fried).
Grind the above five ingredients into powder. Brew Zhu Ye (Bamboo Leaf) in water to obtain 6-7 he. Drink while hot, mixing in three Fang Cun Bi of Chang Shan Powder. Take one dose before onset. If cured, stop; if not, take two more Cun Bi just before onset. Adjust dosage for elderly and children as appropriate. Avoid Hai Zao (Seaweed), Song Cai (Chinese Cabbage), raw Cong (Scallion), and raw vegetables.
Another Prescription for Malaria Regardless of Duration, Wu Mei Pill.
Wu Mei (Mume Fruit Flesh, 3 liang, roasted), Cong Rong (Cistanche Stem, 3 liang), Tao Ren (Peach Seed, 3 liang, roasted, skin removed), Chang Shan (Dichroa Root, 3 liang, roasted), Sheng Ma (Cimicifuga Rhizome, 2 liang, honey-fried), Gui Xin (Cinnamon Twig Heart, 2 liang), Gan Cao (Licorice Root, 2 liang, honey-fried).
Grind the above seven ingredients into powder. Mix with honey to form pills the size of wu zi (wu-tzu seeds). Take twenty pills with wine before onset, and another twenty pills approaching onset. No dietary restrictions apply, except that violating them hinders recovery. Water administration is also acceptable. The medicine may cause vomiting or diarrhea, or neither; do not panic. Taking it frequently every five to six days is beneficial. Avoid Hai Zao (Seaweed), Song Cai (Chinese Cabbage), raw Cong (Scallion), and raw vegetables. (Another version includes San Dou [Soybean] 3 liang, roasted, same as Wen Zhong's Emergency Prescription, both from Volume I.)
Recent Effective Prescription for Stubborn Chronic Malaria, Chang Shan Wine.
Chang Shan (Dichroa Root, 3 liang), Bie Jia (Turtle Shell, 2 liang, roasted), Ling Li Jia (Pangolin Scales, 1 liang, roasted), Wu Zei Gu (Cuttlebone, 1 liang, roasted), Wu Mei (Mume Fruit Flesh, 7 pieces), Tao Ren (Peach Seed, 49 pieces, skin and tip removed, pounded into paste), Zhu Ye (Bamboo Leaf, cut 1 sheng), Dou (Fermented Soybean, 3 he, roasted until fragrant), Cong Bai (Scallion White, cut 1 sheng).
Finely chop the above nine ingredients. Soak in three sheng of wine for two nights. Take one he warm on an empty stomach in the early morning. Wait a while to induce vomiting. If no vomiting occurs, take it after noon. If not cured after four doses, repeat every other day according to the previous method; it will surely cure. Within ten days after recovery, avoid cold water, slippery foods, Ren Xian Cai (Amaranthus manihot), and raw vegetables. Rest as usual.