夫伤寒二日。阳明受病。阳明者胃之经也。主于肌肉。其脉络于鼻。入于目。故得病二
日。
也。
治伤寒二日。阳明受病。阳明者主于肌肉。其气往来寒热。鼻干不可眠卧。面赤
身热。
桂枝（一两） 附子（一两炮裂去皮脐） 甘草（半两炙微赤锉） 赤芍药（半两）
上件药。捣筛为散。每服三钱。以水一中盏。入生姜半分。枣三枚。煎至六分。去滓。
不计时候。稍热频服。汗出即愈。
治伤寒二日。头痛鼻干。面赤壮热。四肢烦疼。宜服人参汤方。
人参（三分去芦头） 诃黎勒皮（三分） 干姜〔三（一）分炮裂锉〕 桂枝（三分） 赤
茯苓
〔一（三）分〕 附子（三分炮裂去皮脐） 甘草（一分炙微赤锉）
上件药。捣筛为散。每服三钱。以水一中盏。煎至六分。去滓。不计时候温服。频服之
。汗出瘥。
治伤寒二日。头痛发热。烦闷。宜服麻黄汤方。
麻黄（一两去根节） 桂心（三分） 石膏（三分） 黄芩（半两） 甘草（一分炙微
赤锉） 赤
芍药（半两） 杏仁（二十一枚汤浸去皮尖双仁麸炒微黄）
上件药。捣筛为散。每服四钱。以水一中盏。入生姜半分。煎至六分。去滓。不计时候
。稍热频服。汗出愈。
治伤寒二日。头痛壮热。骨节烦疼。宜服解肌汤方。
干姜（一两炮裂锉） 麻黄（一两去根节） 赤芍药（三分） 黄芩（三分） 石膏（一
两）
上件药。捣筛为散。每服五钱。以水一大盏。入葱白二茎。豉半合。煎至五分。去滓。
不计时候。稍热服。如人行三五里再服。汗出瘥。
治伤寒二日。皮肤烦（顽）痛。项强。四肢烦疼。宜服吴茱萸散方。
吴茱萸（一两汤浸七遍焙干微炒） 当归（一两锉微炒） 芎 （一两） 附子（一两
炮裂去
皮脐
两去目
及闭
上件药。捣筛为散。每服五钱。以水一大盏。入生姜半分。枣三枚。煎至七分。去滓。
不计时候。稍热分为二服。频服。以衣覆取汗出瘥。
治伤寒二日。头项强。四肢烦疼。宜服荆芥散方。
荆芥（一两） 附子（一两炮裂去皮脐） 前胡（一两） 麻黄（二两去根节） 甘草
（半两炙
微赤锉） 白术（一两） 人参（一两去芦头） 陈橘皮（一两汤浸去白瓤焙）
上件药。捣筛为散。每服四钱。以水一中盏。入生姜半分。枣三枚。煎至六分。去滓。
不计时候稍热服。以衣覆出汗。
治伤寒二日不解。宜服发汗白薇散方。
白薇（半两） 麻黄（一两半去根节） 贝母（三分煨令微黄） 杏仁（三分汤浸去皮
尖双仁
麸炒微黄）
上件药。捣细罗为散。每服。不计时候。以温酒服二钱。衣盖出汗愈。
治伤寒二日。头项四肢。烦热疼痛。宜服柴胡散方。
柴胡（一两去苗） 人参（一两去芦头） 甘草（一两炙微赤锉） 麻黄（一两半去根
节） 黄
芩（一两） 赤芍药（一两） 桂心（一两） 石膏（二两） 葛根（一两锉）
上件药。捣筛为散。每服四钱。以水一中盏。入生姜半分。枣三枚。煎至六分。去滓。
不计时候稍热服。以衣盖取汗。如人行五里未汗再服。
治伤寒二日。心中悸而烦者。宜服建中汤方。
桂心（一两） 甘草（一两炙微赤锉） 白芍药（一两） 桔梗（一两去芦头） 人参
（一两去
芦头） 白术（一两） 陈橘皮（一两汤浸去白瓤焙） 浓朴（一两去粗皮涂生姜汁炙令香
熟）
上件药。捣筛为散。每服四钱。以水一中盏。入生姜半分。枣三枚。煎至六分。去滓。
不计时候温服。
治伤寒二日。头疼壮热。发表附子散方。
附子（一两炮裂去皮脐） 桂心（一两） 麻黄（一两去根节） 白术（一两） 吴茱
萸（半两
汤浸七遍焙干微炒）
上件药。捣罗为散。每服二钱。以水一中盏。入生姜半分。枣三枚。煎至六分。去滓。
不计时候热服。宜频服。令有汗出即瘥。
治伤寒二日。发汗立效方。
附子（半两去皮脐） 白附子（一分） 半夏〔半两（分）〕
上件药。并生捣。细罗为散。每服一钱。以水一中盏。入生姜半分。煎至六分。不计时
候。和滓热服。衣覆出汗。
治伤寒二日。痰逆头疼。四肢壮热。宜服半夏散方。
半夏（一两水煮一伏时晒干） 泽泻（一两） 桂心（一两） 干姜（一分炮裂锉） 甘
草（一
分炙微赤锉）
上件药。捣细罗为散。每服一钱。以水一中盏。入生姜半分。煎至六分。不计时候。和
滓热服。
治伤寒二日。头痛壮热。宜服走马散方。
草乌头（半两烧灰） 桂心（半两） 硫黄（半分细研）
上件药。捣细罗为散。每服一钱。以水一中盏。入生姜半分。煎至六分。不计时候。和
滓稍热频服。盖出汗瘥。
治伤寒二日。头痛。腰脊强硬。憎寒壮热。遍身疼痛。宜服霹雳散方。\x
大黑附子（一枚入急火内烧唯存心少多在临出火时便用瓷器合盖不令去却烟焰）
上捣。细罗为散。每服。（一钱。）不计时候。以热酒调下。汗出立瘥。
On the second day of *Shanghan* (Cold Damage disease), the pathogen affects the Yangming channel. The Yangming channel belongs to the Stomach meridian and primarily governs the muscles. Its collaterals connect to the nose and enter the eyes. Therefore, after two days of illness, the following manifestations occur:
For treating Shanghan on the second day where the Yangming channel is affected: The Yangming channel governs the muscles; the patient presents with alternating aversion to cold and fever, dryness of the nose, inability to sleep, flushed face, and body heat.
Prescription: Guizhi Tang (Cinnamon Twig Decoction) [Guizhi/Cinnamomi Ramulus] (1 liang), Fuzi (Aconiti Lateralis Radix Praeparata) [1 liang, processed until cracked, peel and lateral root removed], Gancao (Glycyrrhizae Radix et Rhizoma) [0.5 liang, honey-fried until slightly red and chopped], Chishao Yao (Paeoniae Radix Rubra) [0.5 liang].
The above herbs are crushed, sifted, and made into a powder. Each dose consists of 3 qian. Boil with one zhong zhan (approx. 200-300ml) of water, add 0.5 fen of Shengjiang (Zingiberis Rhizoma Recens/Fresh Ginger), and three dates (Jujubae Fructus). Decoct until the volume reduces to 6/10. Strain the dregs. Take frequently while slightly warm, regardless of meal times. Recovery occurs upon sweating.
For treating Shanghan on the second day presenting with headache, nasal dryness, flushed face, high fever, and vexatious pain in the four limbs: Ren Shen Tang (Ginseng Decoction) is indicated.
Prescription: Renshen (Panacis Ginseng Radix) [3 qian, rhizome removed], Helile Pi (Terminaliae Chebulae Pericarpium) [3 qian], Gan Jiang (Zingiberis Rhizoma) [3 qian, processed until cracked and chopped], Guizhi (Cinnamomi Ramulus) [3 qian], Chi Fu Ling (Poria cum Risu Rubrum) [3 qian], Fuzi (Aconiti Lateralis Radix Praeparata) [3 qian, processed until cracked, peel and lateral root removed], Gancao (Glycyrrhizae Radix et Rhizoma) [1 qian, honey-fried until slightly red and chopped].
The above herbs are crushed, sifted, and made into a powder. Each dose consists of 3 qian. Boil with one zhong zhan of water until the volume reduces to 6/10. Strain the dregs. Take warm, regardless of meal times, and frequently. Recovery occurs upon sweating.
For treating Shanghan on the second day presenting with headache, fever, and mental restlessness: Mahuang Tang (Ephedra Decoction) is indicated.
Prescription: Mahuang (Ephedrae Herba) [1 liang, roots and nodes removed], Guixin (Cinnamomi Ramulus) [3 qian], Shigao (Gypsum Fibrosum) [3 qian], Huangqin (Scutellariae Radix) [0.5 liang], Gancao (Glycyrrhizae Radix et Rhizoma) [1 qian, honey-fried until slightly red and chopped], Chishao Yao (Paeoniae Radix Rubra) [0.5 liang], Xingren (Armeniacae Semen Amarum) [21 seeds, soaked in hot water, skin and tips removed, double-kernel wheat bran fried until slightly yellow].
The above herbs are crushed, sifted, and made into a powder. Each dose consists of 4 qian. Boil with one zhong zhan of water, add 0.5 fen of Shengjiang (Fresh Ginger), and decoct until the volume reduces to 6/10. Strain the dregs. Take frequently while slightly warm, regardless of meal times. Recovery occurs upon sweating.
For treating Shanghan on the second day presenting with headache, high fever, and vexatious pain in the bone joints: Jie Ji Tang (Muscle-Releasing Decoction) is indicated.
Prescription: Gan Jiang (Zingiberis Rhizoma) [1 liang, processed until cracked and chopped], Mahuang (Ephedrae Herba) [1 liang, roots and nodes removed], Chishao Yao (Paeoniae Radix Rubra) [3 qian], Huangqin (Scutellariae Radix) [3 qian], Shigao (Gypsum Fibrosum) [1 liang].
The above herbs are crushed, sifted, and made into a powder. Each dose consists of 5 qian. Boil with one da zhan (approx. 400-500ml) of water, add two stalks of Congbai (Allii Fistulosi Bulbus/White Part of Scallion) and Ban He (Sojae Preparata/Vinegar-processed Soybean), and decoct until the volume reduces to 5/10. Strain the dregs. Take while slightly warm, regardless of meal times. If no sweat occurs after walking for 3-5 li, take another dose. Recovery occurs upon sweating.
For treating Shanghan on the second day presenting with stubborn skin pain, neck stiffness, and vexatious pain in the four limbs: Wu Zhu Yu San (Evodia Powder) is indicated.
Prescription: Wu Zhuyu (Euodiae Fructus) [1 liang, soaked in hot water seven times, baked dry and lightly fried], Danggui (Angelicae Sinensis Radix) [1 liang, chopped and lightly fried], Xiong (Ligustici Chuanxiong Rhizoma) [1 liang], Fuzi (Aconiti Lateralis Radix Praeparata) [1 liang, processed until cracked, peel and lateral root removed].
The above herbs are crushed, sifted, and made into a powder. Each dose consists of 5 qian. Boil with one da zhan of water, add 0.5 fen of Shengjiang (Fresh Ginger) and three dates, and decoct until the volume reduces to 7/10. Strain the dregs. Divide into two doses, take frequently while slightly warm, regardless of meal times. Cover with clothing to induce sweating. Recovery occurs upon sweating.
For treating Shanghan on the second day presenting with head and neck stiffness, and vexatious pain in the four limbs: Jingjie San (Schizonepeta Powder) is indicated.
Prescription: Jingjie (Schizonepetae Spica) [1 liang], Fuzi (Aconiti Lateralis Radix Praeparata) [1 liang, processed until cracked, peel and lateral root removed], Qianhu (Peucedani Radix) [1 liang], Mahuang (Ephedrae Herba) [2 liang, roots and nodes removed], Gancao (Glycyrrhizae Radix et Rhizoma) [0.5 liang, honey-fried until slightly red and chopped], Baizhu (Atractylodis Macrocephalae Rhizoma) [1 liang], Renshen (Panacis Ginseng Radix) [1 liang, rhizome removed], Chenjupi (Citri Reticulatae Pericarpium) [1 liang, soaked in hot water, white pith removed, and baked dry].
The above herbs are crushed, sifted, and made into a powder. Each dose consists of 4 qian. Boil with one zhong zhan of water, add 0.5 fen of Shengjiang (Fresh Ginger) and three dates, and decoct until the volume reduces to 6/10. Strain the dregs. Take while slightly warm, regardless of meal times. Cover with clothing to induce sweating.
For treating unresolved Shanghan on the second day: Faxian Baiwei San (Sweating Baiwei Powder) is indicated.
Prescription: Baiwei (Cynanchi Atrati Radix) [0.5 liang], Mahuang (Ephedrae Herba) [1.5 liang, roots and nodes removed], Beimu (Fritillariae Thunbergii Bulbus) [3 qian, roasted until slightly yellow], Xingren (Armeniacae Semen Amarum) [3 qian, soaked in hot water, skin and tips removed, double-kernel wheat bran fried until slightly yellow].
The above herbs are finely ground and sifted through a fine sieve to make a powder. Each dose consists of 2 qian. Take with warm wine, regardless of meal times. Cover with blankets to induce sweating. Recovery occurs upon sweating.
For treating Shanghan on the second day presenting with vexatious heat and pain in the head, neck, and four limbs: Chai Hu San (Bupleurum Powder) is indicated.
Prescription: Chaihu (Bupleuri Radix) [1 liang, sprouts removed], Renshen (Panacis Ginseng Radix) [1 liang, rhizome removed], Gancao (Glycyrrhizae Radix et Rhizoma) [1 liang, honey-fried until slightly red and chopped], Mahuang (Ephedrae Herba) [1.5 liang, roots and nodes removed], Huangqin (Scutellariae Radix) [1 liang], Chishao Yao (Paeoniae Radix Rubra) [1 liang], Guixin (Cinnamomi Ramulus) [1 liang], Shigao (Gypsum Fibrosum) [2 liang], Gegen (Puerariae Lobatae Radix) [1 liang, chopped].
The above herbs are crushed, sifted, and made into a powder. Each dose consists of 4 qian. Boil with one zhong zhan of water, add 0.5 fen of Shengjiang (Fresh Ginger) and three dates, and decoct until the volume reduces to 6/10. Strain the dregs. Take while slightly warm, regardless of meal times. Cover with blankets to induce sweating. If no sweat occurs after walking five li, take another dose.
For treating Shanghan on the second day presenting with palpitations and mental restlessness: Jian Zhong Tang (Middle-Building Decoction) is indicated.
Prescription: Guixin (Cinnamomi Ramulus) [1 liang], Gancao (Glycyrrhizae Radix et Rhizoma) [1 liang, honey-fried until slightly red and chopped], Baishao Yao (Paeoniae Radix Alba) [1 liang], Jiegeng (Platycodonis Radix) [1 liang, rhizome removed], Renshen (Panacis Ginseng Radix) [1 liang, rhizome removed], Baizhu (Atractylodis Macrocephalae Rhizoma) [1 liang], Chenjupi (Citri Reticulatae Pericarpium) [1 liang, soaked in hot water, white pith removed, and baked dry], Nongpo (Magnoliae Officinalis Cortex) [1 liang, coarse bark removed, coated with fresh ginger juice, and roasted until fragrant and cooked].
The above herbs are crushed, sifted, and made into a powder. Each dose consists of 4 qian. Boil with one zhong zhan of water, add 0.5 fen of Shengjiang (Fresh Ginger) and three dates, and decoct until the volume reduces to 6/10. Strain the dregs. Take warm, regardless of meal times.
For treating Shanghan on the second day presenting with headache and high fever: Fabiao Fuzi San (Exterior-Releasing Aconite Powder) is indicated.
Prescription: Fuzi (Aconiti Lateralis Radix Praeparata) [1 liang, processed until cracked, peel and lateral root removed], Guixin (Cinnamomi Ramulus) [1 liang], Mahuang (Ephedrae Herba) [1 liang, roots and nodes removed], Baizhu (Atractylodis Macrocephalae Rhizoma) [1 liang], Wu Zhuyu (Euodiae Fructus) [0.5 liang, soaked in hot water seven times, baked dry and lightly fried].
The above herbs are finely ground and sifted through a fine sieve to make a powder. Each dose consists of 2 qian. Boil with one zhong zhan of water, add 0.5 fen of Shengjiang (Fresh Ginger) and three dates, and decoct until the volume reduces to 6/10. Strain the dregs. Take hot, regardless of meal times, and frequently. Recovery occurs upon inducing sweating.
For treating Shanghan on the second day, an immediate sweating prescription:
Prescription: Fuzi (Aconiti Lateralis Radix Praeparata) [0.5 liang, peel and lateral root removed], Baifuzi (Aconiti Kusnezoffii Radix) [1 qian], Banxia (Pinelliae Rhizoma) [0.5 liang].
The above herbs are all raw-crushed and finely ground/sifted to make a powder. Each dose consists of 1 qian. Boil with one zhong zhan of water, add 0.5 fen of Shengjiang (Fresh Ginger), and decoct until the volume reduces to 6/10. Take the liquid and dregs together while hot, regardless of meal times. Cover with clothing to induce sweating.
For treating Shanghan on the second day presenting with rebellious phlegm, headache, and high fever in the four limbs: Banxia San (Pinellia Powder) is indicated.
Prescription: Banxia (Pinelliae Rhizoma) [1 liang, boiled for one shichen (2 hours), then dried], Zexie (Alismatis Rhizoma) [1 liang], Guixin (Cinnamomi Ramulus) [1 liang], Gan Jiang (Zingiberis Rhizoma) [1 qian, processed until cracked and chopped], Gancao (Glycyrrhizae Radix et Rhizoma) [1 qian, honey-fried until slightly red and chopped].
The above herbs are finely ground and sifted through a fine sieve to make a powder. Each dose consists of 1 qian. Boil with one zhong zhan of water, add 0.5 fen of Shengjiang (Fresh Ginger), and decoct until the volume reduces to 6/10. Take the liquid and dregs together while hot, regardless of meal times.
For treating Shanghan on the second day presenting with headache and high fever: Zouma San (Running Horse Powder) is indicated.
Prescription: Caowutou (Aconiti Radix) [0.5 liang, burned to ash], Guixin (Cinnamomi Ramulus) [0.5 liang], Liuhuang (Sulfur) [0.5 fen, finely ground].
The above herbs are finely ground and sifted through a fine sieve to make a powder. Each dose consists of 1 qian. Boil with one zhong zhan of water, add 0.5 fen of Shengjiang (Fresh Ginger), and decoct until the volume reduces to 6/10. Take the liquid and dregs together while slightly warm, frequently, regardless of meal times. Cover with blankets to induce sweating. Recovery occurs upon sweating.
For treating Shanghan on the second day presenting with headache, stiffness of the waist and spine, aversion to cold with high fever, and generalized body pain: Pili San (Thunderbolt Powder) is indicated.
Prescription: Dahei Fuzi (Aconiti Lateralis Radix Praeparata, Black Variety) [1 piece, placed in intense fire to burn until only the heart/core remains; cover immediately with a porcelain vessel upon removal from fire to prevent smoke/flame loss].
The above herb is crushed, finely ground, and sifted through a fine sieve to make a powder. Each dose consists of 1 qian. Take mixed with hot liquor, regardless of meal times. Recovery occurs immediately upon sweating.