夫伤寒一二日。或服汤药吐下之后。身重头痛。腰背烦闷。面赤斑斑如锦纹。狂言而走
。或见鬼神。其脉浮大而数。咽喉痛。下脓血。此名阳毒。五日可疗。七日不可疗也。
治伤寒一日。便成阳毒。或服药发汗吐下之后。毒瓦斯不解。身重背强烦闷。狂言
。或走
川升麻（一两） 当归（半两锉微炒） 黄芩（三分） 犀角屑（半两） 射干（一两）
黄连（
三分去须） 地骨皮（三分） 甘草（半两炙微赤锉）
上件药。捣筛为散。每服四钱。以水一中盏。煎至六分。去滓。不计时候温服。
治阳毒伤寒。身体疼痛。头面如火。胸心烦热而渴。小便赤黄。不得睡卧。宜服麦
门冬
麦门冬（一两去心焙） 子芩（三分） 葛根（一两锉） 川升麻（半两） 柴胡（一
两去苗）
玄参
牙硝
（一两）
上件药。捣粗罗为散。每服四钱。以水一中盏。煎至六分。去滓。不计时候温服。
治阳毒伤寒。狂言乱走。面赤斑斑。咽喉干痛。心胸烦满。四肢拘急。小便赤黄
。宜服
犀角屑（半两） 射干（三分） 柴胡（一两去苗） 川大黄（三分锉碎微炒） 川升
麻（一两）
甘草（半两炙微赤锉） 黄芩（三分） 川芒硝（一两） 麦门冬（一两去心焙）
上件药。捣粗罗为散。每服四钱。以水一中盏。入淡竹叶三七片。小麦五十粒。煎至六
分。去滓。不计时候温服。
治阳毒伤寒。壮热头痛。肢体烦重。口干心躁。宜服石膏散方。
石膏（一两） 知母 柴胡（去苗） 麻黄（去根节） 甘草（炙微赤锉） 黄芩 赤
芍药 防
风（去芦头） 赤茯苓 川升麻 甘菊花（以上各半两）
上件药。捣筛为散。每服四钱。以水一中盏。入生姜半分。葱白七寸。豆豉一百粒。煎
至六分。去滓。不计时候温服。
治阳毒伤寒未解。热结在内。恍惚如狂者。宜服大黄散方。
川大黄（一两半锉碎微炒） 桂心（三分） 甘草（一两炙微赤锉） 川芒硝（二两） 木
通（
一两锉） 大腹皮（一两锉） 桃仁（廿枚汤浸去皮尖双仁麸炒微黄）
上件药。捣粗罗为散。每服四钱。以水一中盏。煎至六分。去滓。不计时候温服。以通
利为度。
治阳毒伤寒。头昏身重。咽喉唇干。腮赤。狂言欲走。心胸胀满。呕逆不下饮食
。面色
柴胡（一两去苗） 地骨皮 木香 麻黄（去根节） 甘草（炙微赤锉） 川升麻 栝
蒌根
人参（去芦头） 赤茯苓 木通（锉）（以上各半两）
上件药。捣粗罗为散。每服四钱。以水一中盏。煎至六分。去滓。不计时候温服。
治阳毒伤寒壮热。百节疼痛。宜服柴胡散方。
柴胡（一两半去苗） 川升麻（二两） 黄芩（二两） 赤芍药（一两） 木香（大青）
（一两）
石膏
浸去皮尖
双仁麸
上件药。捣粗罗为散。每服四钱。以水一中盏。入生姜半分。豉一百粒。煎至六分。去
滓。不计时候温服。
治阳毒伤寒。项背汗出。急强恶风者。宜服桂枝麻黄散方。
桂枝 麻黄（去根节） 甘草（炙微赤锉） 赤芍药 葛根（锉） 杏仁（汤浸去皮尖
双仁炒
微黄）（以上各一两）
上件药。捣筛为散。每服四钱。以水一中盏。入生姜半分。煎至六分。去滓。不计时候
热服。衣覆取汗。如人行十里未有汗。再良久以葱豉粥投之。
治阳毒伤寒。服桂枝汤大汗出后。大渴烦躁不解。脉洪大者。白虎汤主之。
知母（一两） 石膏（二两捣碎） 甘草（一两炙微赤锉） 粳米（一合）
上件药。细锉。以水二大盏。煮米熟为度。去滓。不计时候。分温三服。
治阳毒伤寒。四肢壮热。心膈烦躁。呕吐不止。宜服此方。
柴胡（去苗） 黄芩 人参（去芦头） 甘草（炙微赤锉） 麦门冬（去心焙）（以上
各一两）
半夏（半两汤洗七遍去滑）
上件药。捣粗罗为散。每服四钱。水一中盏。入竹叶二七片。生姜半分。煎至六分。去
滓。不计时候温服。
治阳毒伤寒。五六日以上。但胸中烦热干呕。宜服栝蒌散方。
栝蒌 柴胡（去苗） 知母 黄芩 甘草（炙微赤锉）（以上各一两半）
上件药。捣筛为散。每服四钱。以水一中盏。入生姜半分。煎至六分。去滓。不计时候
温服。
治阳毒伤寒。脉洪大。心中悸状。宜服甘草散方。
甘草（炙微赤锉） 桂心 茯神 人参（去芦头） 阿胶（捣碎炒令黄燥） 麦门冬（去
心）（
以上各一两） 生干地黄（二两） 麻黄（二两去根节）
上件药。捣筛为散。每服四钱。以水一中盏。入生姜半分。煎至六分。去滓。不计时候
温服。
治阳毒伤寒。气盛。昏昏如醉。热躁烦渴。口苦舌干。宜服黄芩散方。
黄芩（一两） 川升麻（一两） 赤芍药（半两） 麦门冬（半两去心） 石膏（二两）
柴胡（
一两去苗） 甘草（半两炙微赤锉）
上件药。捣筛为散。每服四钱。以水一中盏。煎至六分。去滓。不计时候温服。
治阳毒伤寒。心躁烦闷。恍惚如狂。结热不散。宜服牛黄丸方。
牛黄（半两细研） 龙脑（一分细研） 天竺黄（半两细研） 犀角屑 羚羊角屑 朱
砂（细
研水
香
（一钱
上件药。捣罗为末。入前研了药。更研令匀。以炼蜜和捣三二百杵。丸如梧桐子大。每
服。不计时候。以温水嚼下十五丸。
治阳毒伤寒。烦热。大便不通方。
川大黄（一两锉碎微炒） 川芒硝（半两）
上件药。捣筛。以水一大盏。煎至七分。去滓。不计时候。分温二服。如人行五七里再
服。当利下恶物。
治阳毒伤寒。毒瓦斯在脏。狂言妄语。欲走起者。宜服此方。
龙胆（一两去芦头） 铁粉（二两）
上件药。细罗为散。每服。不计时候。以磨刀水调下一钱。
In the first or second day of Shanghan (Cold Damage), or after taking decoctions to induce vomiting or purging, symptoms such as heaviness of the body, headache, and vexation and stuffiness in the lower back may occur. The face is red with mottled patterns like brocade, accompanied by delirious speech and running about, or hallucinations of seeing ghosts and spirits. The pulse is floating, large, and rapid; there is sore throat, and pus and blood in the stool. This is named Yang Du (Yang Toxin). It can be treated within five days, but treatment after seven days is difficult.
For cases where Shanghan develops into Yang Du within one day, or where the pathogenic toxin remains unresolved after inducing sweating, vomiting, or purging, symptoms include body heaviness, stiffness of the back, vexation and stuffiness, delirious speech, and running about.
Chuan Shengma (Rhizoma Cimicifugae) (1 liang) Danggui (Radix Angelicae Sinensis) (0.5 liang, sliced, slightly stir-fried) Huangqin (Scutellariae Radix) (3 fen) Xijiao (Hornis Rhinocerotis) (0.5 liang, in slices) Shegan (Radix Belamcandae) (1 liang)
Huanglian (Rhizoma Coptidis) (3 fen, remove the rootlets) Digupi (Cortices Lycii) (3 fen) Gancao (Radix Glycyrrhizae) (0.5 liang, honey-fried until slightly red, sliced)
The above medicines are crushed, sifted, and made into a powder. Each dose is 4 qian, boiled with 1 zhongzhan (approx. 200ml) of water until reduced to 6 fen (approx. 120ml). Strain the dregs. Take warm at any time.
For Yang Du Shanghan presenting with body pain, head and face feeling hot like fire, vexation and heat in the chest and heart with thirst, dark yellow urine, and inability to sleep, the Maidong Tang is suitable.
Maidong (Radix Ophiopogonis) (1 liang, remove the heart, baked) Zixin (i.e., Huangqin, Scutellariae Radix) (3 fen) Gegen (Puerariae Radix) (1 liang, sliced) Chuan Shengma (Rhizoma Cimicifugae) (0.5 liang) Chaihu (Bupleuri Radix) (1 liang, remove the crown)
Xuanshen (Radix Scrophulariae)
Yaxiao (Natrii Sulfas) (1 liang)
The above medicines are coarsely sieved and made into a powder. Each dose is 4 qian, boiled with 1 zhongzhan of water until reduced to 6 fen. Strain the dregs. Take warm at any time.
For Yang Du Shanghan presenting with delirious speech, running about, red face with mottling, dry and painful throat, vexation and fullness in the chest and heart, spasm and tightness of the four limbs, and dark yellow urine, this formula is suitable.
Xijiao (Hornis Rhinocerotis) (0.5 liang, in slices) Shegan (Radix Belamcandae) (3 fen) Chaihu (Bupleuri Radix) (1 liang, remove the crown) Chuan Dahuang (Rhei Radix et Rhizoma) (3 fen, sliced, slightly stir-fried) Chuan Shengma (Rhizoma Cimicifugae) (1 liang)
Gancao (Radix Glycyrrhizae) (0.5 liang, honey-fried until slightly red, sliced) Huangqin (Scutellariae Radix) (3 fen) Chuan Mangxiao (Natrii Sulfas) (1 liang) Maidong (Radix Ophiopogonis) (1 liang, remove the heart, baked)
The above medicines are coarsely sieved and made into a powder. Each dose is 4 qian, boiled with 1 zhongzhan of water, adding 37 slices of Danzhuye (Leaves of Lophatherum) and 50 grains of Xiaomai (Frumentum Triticum), until reduced to 6 fen. Strain the dregs. Take warm at any time.
For Yang Du Shanghan presenting with high fever, headache, heavy and vexed limbs, dry mouth, and mental restlessness, the Shigao San is suitable.
Shigao (Gypsum Fibrosum) (1 liang) Zhimu (Rhizoma Anemarrhenae) Chaihu (Bupleuri Radix) (remove the crown) Mahuang (Herba Ephedrae) (remove roots and joints) Gancao (Radix Glycyrrhizae) (honey-fried until slightly red, sliced) Huangqin (Scutellariae Radix) Chishao Yao (Radix Paeoniae Rubra) Fangfeng (Radix Saposhnikoviae) (remove the rhizome tip) Chifuling (Poria cum Ligno Rubrum) Chuan Shengma (Rhizoma Cimicifugae) Gan Juhua (Flos Chrysanthemi) (all 0.5 liang)
The above medicines are crushed, sifted, and made into a powder. Each dose is 4 qian, boiled with 1 zhongzhan of water, adding 0.5 ban of Shengjiang (Rhizoma Zingiberis Recens), 7 cun of Congbai (White part of Allium fistulosum), and 100 grains of Douchi (Soybean, Fructus Sojae Preparatus), until reduced to 6 fen. Strain the dregs. Take warm at any time.
For unresolved Yang Du Shanghan with heat binding internally and mental confusion resembling mania, the Dahuang San is suitable.
Chuan Dahuang (Rhei Radix et Rhizoma) (1.5 liang, sliced, slightly stir-fried) Guixin (Cortex Cinnamomi) (3 fen) Gancao (Radix Glycyrrhizae) (1 liang, honey-fried until slightly red, sliced) Chuan Mangxiao (Natrii Sulfas) (2 liang) Mutong (Caulis Akebiae) (1 liang, sliced) Dafupi (Pericarpium Arecae) (1 liang, sliced) Taoren (Semen Persicae) (20 pieces, soaked in warm water, skin and tips removed, double-kernel, bran-fried until slightly yellow)
The above medicines are coarsely sieved and made into a powder. Each dose is 4 qian, boiled with 1 zhongzhan of water until reduced to 6 fen. Strain the dregs. Take warm at any time. Adjust dosage according to bowel movement.
For Yang Du Shanghan presenting with dizziness, body heaviness, dry throat and lips, red cheeks, delirious speech, desire to run, chest and heart distension and fullness, vomiting, and inability to eat, [face color description missing in source].
Chaihu (Bupleuri Radix) (1 liang, remove the crown) Digupi (Cortices Lycii) Muxiang (Radix Aucklandiae) Mahuang (Herba Ephedrae) (remove roots and joints) Gancao (Radix Glycyrrhizae) (honey-fried until slightly red, sliced) Chuan Shengma (Rhizoma Cimicifugae) Gualougen (Radix Trichosanthis)
Renshen (Radix Ginseng) (remove the rhizome tip) Chifuling (Poria cum Ligno Rubrum) Mutong (Caulis Akebiae) (sliced) (all 0.5 liang)
The above medicines are coarsely sieved and made into a powder. Each dose is 4 qian, boiled with 1 zhongzhan of water until reduced to 6 fen. Strain the dregs. Take warm at any time.
For Yang Du Shanghan with high fever and pain in all joints, the Chaihu San is suitable.
Chaihu (Bupleuri Radix) (1.5 liang, remove the crown) Chuan Shengma (Rhizoma Cimicifugae) (2 liang) Huangqin (Scutellariae Radix) (2 liang) Chishao Yao (Radix Paeoniae Rubra) (1 liang) Muxiang (Radix Aucklandiae) Daqing (Indici Folium) (1 liang)
Shigao (Gypsum Fibrosum)
Soaked, skin and tips removed
Double-kernel bran-
The above medicines are coarsely sieved and made into a powder. Each dose is 4 qian, boiled with 1 zhongzhan of water, adding 0.5 ban of Shengjiang (Rhizoma Zingiberis Recens) and 100 grains of Chi (Douchi), until reduced to 6 fen. Strain the dregs. Take warm at any time.
For Yang Du Shanghan presenting with sweating on the neck and back, acute stiffness, and aversion to wind, the Guizhi Mahuang San is suitable.
Guizhi (Ramulus Cinnamomi) Mahuang (Herba Ephedrae) (remove roots and joints) Gancao (Radix Glycyrrhizae) (honey-fried until slightly red, sliced) Chishao Yao (Radix Paeoniae Rubra) Gegen (Puerariae Radix) (sliced) Xingren (Semen Pruni Armeniacae) (soaked in warm water, skin and tips removed, double-kernel, fried until slightly yellow) (all 1 liang)
The above medicines are crushed, sifted, and made into a powder. Each dose is 4 qian, boiled with 1 zhongzhan of water, adding 0.5 ban of Shengjiang (Rhizoma Zingiberis Recens), until reduced to 6 fen. Strain the dregs. Take hot, cover with clothing to induce sweating. If no sweat occurs after walking for ten li, wait a while and administer Congchi Zhou (Congee with Scallion and Fermented Soybean).
After taking Guizhi Tang for Yang Du Shanghan, if profuse sweating occurs followed by extreme thirst, unrelieved irritability, and a flooding pulse, Baihu Tang is indicated.
Zhimu (Rhizoma Anemarrhenae) (1 liang) Shigao (Gypsum Fibrosum) (2 liang, crushed) Gancao (Radix Glycyrrhizae) (1 liang, honey-fried until slightly red, sliced) Jingmi (Oryza Sativa) (1 he)
The above medicines are finely sliced. Boil with two large zhanzhan of water until the rice is cooked. Strain the dregs. Divide into three warm doses, taken at any time.
For Yang Du Shanghan presenting with high fever in the four limbs, irritability in the chest and diaphragm, and incessant vomiting, this formula is suitable.
Chaihu (Bupleuri Radix) (remove the crown) Huangqin (Scutellariae Radix) Renshen (Radix Ginseng) (remove the rhizome tip) Gancao (Radix Glycyrrhizae) (honey-fried until slightly red, sliced) Maidong (Radix Ophiopogonis) (remove the heart, baked) (all 1 liang)
Banxia (Rhizoma Pinelliae) (0.5 liang, washed seven times in warm water to remove slipperiness)
The above medicines are coarsely sieved and made into a powder. Each dose is 4 qian, boiled with 1 zhongzhan of water, adding fourteen slices of Zhuye (Leaf of Bambusa) and 0.5 ban of Shengjiang (Rhizoma Zingiberis Recens), until reduced to 6 fen. Strain the dregs. Take warm at any time.
For Yang Du Shanghan persisting for five to six days or more, presenting only with vexation and heat in the chest and dry retching, the Gualou San is suitable.
Gualou (Fructus Trichosanthis) Chaihu (Bupleuri Radix) (remove the crown) Zhimu (Rhizoma Anemarrhenae) Huangqin (Scutellariae Radix) Gancao (Radix Glycyrrhizae) (honey-fried until slightly red, sliced) (all 1.5 liang)
The above medicines are crushed, sifted, and made into a powder. Each dose is 4 qian, boiled with 1 zhongzhan of water, adding 0.5 ban of Shengjiang (Rhizoma Zingiberis Recens), until reduced to 6 fen. Strain the dregs. Take warm at any time.
For Yang Du Shanghan presenting with a flooding pulse and palpitations in the heart, the Gancao San is suitable.
Gancao (Radix Glycyrrhizae) (honey-fried until slightly red, sliced) Guixin (Cortex Cinnamomi) Fushen (Poria cum Radix) Renshen (Radix Ginseng) (remove the rhizome tip) Ejiao (Colla Corii Asini) (crushed, fried until yellow and dry) Maidong (Radix Ophiopogonis) (remove the heart) (all 1 liang) Sheng Gan Dihuang (Radix Rehmanniae Praeparata) (2 liang) Mahuang (Herba Ephedrae) (2 liang, remove roots and joints)
The above medicines are crushed, sifted, and made into a powder. Each dose is 4 qian, boiled with 1 zhongzhan of water, adding 0.5 ban of Shengjiang (Rhizoma Zingiberis Recens), until reduced to 6 fen. Strain the dregs. Take warm at any time.
For Yang Du Shanghan with excess qi, drowsiness resembling drunkenness, heat and irritability with thirst, bitter taste in the mouth, and dry tongue, the Huangqin San is suitable.
Huangqin (Scutellariae Radix) (1 liang) Chuan Shengma (Rhizoma Cimicifugae) (1 liang) Chishao Yao (Radix Paeoniae Rubra) (0.5 liang) Maidong (Radix Ophiopogonis) (0.5 liang, remove the heart) Shigao (Gypsum Fibrosum) (2 liang)
Chaihu (Bupleuri Radix) (1 liang, remove the crown) Gancao (Radix Glycyrrhizae) (0.5 liang, honey-fried until slightly red, sliced)
The above medicines are coarsely sieved and made into a powder. Each dose is 4 qian, boiled with 1 zhongzhan of water until reduced to 6 fen. Strain the dregs. Take warm at any time.
For Yang Du Shanghan with mental restlessness, vexation, mental confusion resembling mania, and unresolved binding heat, the Niuhuang Wan is suitable.
Niuhuang (Calculus Bovis) (0.5 liang, finely ground) Longnao (Borneolum Syntheticum) (1 fen, finely ground) Tianzhu Huang (Spiralis Bambusae in Taenia) (0.5 liang, finely ground) Xijiao (Hornis Rhinocerotis) Lingyangjiao (Cornu Saigae Tataricae) Zhusha (Cinnabaris) (finely ground, water-washed) Shexiang (Moschus) (1 qian)
The above medicines are pounded into powder. Add the previously ground medicines and grind uniformly. Mix with refined honey and pound 300-200 times. Form pills the size of Sophora seeds. Each dose: take 15 pills, chewed down with warm water, at any time.
For Yang Du Shanghan with vexing heat and constipation.
Chuan Dahuang (Rhei Radix et Rhizoma) (1 liang, sliced, slightly stir-fried) Chuan Mangxiao (Natrii Sulfas) (0.5 liang)
The above medicines are crushed and sifted. Boil with one large zhanzhan of water until reduced to 7 fen. Strain the dregs. Divide into two warm doses, taken at any time. If not effective after walking 5-7 li, take again. Evil matter should be discharged.
For Yang Du Shanghan where the toxic qi is in the zang organs, causing delirious speech and a desire to run and rise, this formula is suitable.
Longdan (Radix Gentianae) (1 liang, remove the rhizome tip) Tie Fen (Plumbum Preparatum) (2 liang)
The above medicines are finely sieved into a powder. Each dose: take 1 qian, mixed with Mo Dao Shui (water used for sharpening knives), at any time.