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Wine is a substance that is extremely hot and toxic, with both its qi (vital energy) and flavor belonging to Yang. It is considered an "formless" entity. If injury occurs due to excessive consumption, the only appropriate treatment is to induce dispersion through sweating; once sweat is excreted, the condition resolves. This is the most excellent method. The next best approach is to promote urination. These two methods eliminate dampness from the upper and lower pathways respectively, leaving no room for wine-induced pathology.

However, those suffering from wine-related ailments often administer Jiuzheng Wan (Alcohol-Steamed Pill), a formula of extreme heat, or employ purgatives such as Qian Niu Zi (Pharbitidis Semen) and Da Huang (Rhei Radix et Rhizoma). This constitutes a grave error: since wine pathogen affects the formless Yuan Qi (Primordial Qi), using purgatives that target formless Yin Blood is fundamentally misguided. Wine's extreme heat already damages Yuan Qi; further aggressive purgation additionally depletes Kidney Water (True Yin) and formless Yin Blood, rendering both deficient. In this state, with Yin Blood already weak and True Water further diminished, Yang Toxic Heat flares up excessively, thereby intensifying Yin Fire. This leads to the exhaustion of Yuan Qi, causing the Seven Spirits (Shen, Hun, Po, Yi, Zhi, Jing, and Shen - mental faculties) to lose their foundation, resulting either in premature death or the development of deficiency-consumption diseases. *Jin Gui Yao Lue* states: "If Jaundice from Wine is treated with purgatives, it may eventually transform into Black Jaundice." One must strictly avoid this contraindication. Instead, one should facilitate the dispersion of dampness through upper and lower pathways, primarily utilizing Jie Cheng Tang (Dreg-Resolving Decoction).

Commentary notes: Wine is actually a tangible substance, sharing the same nature as water and fluid retention. The statement that "formless Yuan Qi is affected, not formless Yin Blood," implies that wine is a damp-heat substance. Upon entering the Stomach, it heats the Qi of the Zang organs. During the process of ascending and descending Qi, Yuan Qi is consumed by half. When it injures the Intestines and Stomach, clear Qi fails to ascend and turbid Qi fails to descend, stagnating in the Qi level—a position devoid of form. Hence, it is termed "formless," unlike water retention which fully settles in the Intestines and Stomach. For instance, when modern individuals consume strong wine, urine output decreases, which serves as verifiable evidence. Therefore, upon injury, diaphoresis (sweating) and resolving turbidity are indicated; heavy and harsh purgatives must not be used. Such drugs cannot enter the Qi level but instead damage formless Yin Blood. However, this implication has caused doubt, leading some to refute it, though detailed refutations are omitted here. Historically, some physicians did use purgatives. This might be applicable if wine accumulation persists for a long time and diaphoresis/resolution fails to cure the condition; in such cases, harsh purgatives might be considered. Thus, practitioners must carefully examine the syndrome and not let literal interpretations obscure the underlying intent.

Annotation explains: When food accumulates and blocks the chest, causing obstruction, the Cun (Inch) pulses at both wrists should reflect the pathology, while the Chi (Cubit) pulses may be absent. What is the rationale? Because food stagnation exists in the chest, emesis (vomiting) is indicated to expel it.

Food represents matter; matter corresponds to Kun Earth, which is associated with the Foot Taiyin Spleen Meridian. The chest is the domain of the Lung. Food injuring the Lung involves Hand Taiyin Metal. Metal governs severing and cutting. Since both Kun Earth and Metal reside in the upper jiao and flourish under Heavenly Qi, and Metal controls Wood, the generating Qi of Liver Wood is suppressed underground. Is this not Wood Depression? By vomiting out the Yin Earth (Spleen/Stomach) matter from the Upper Jiao, Wood Qi becomes free to flow smoothly, resolving the depression. Food blockage in the upper part causes the absence of pulses in the lower part. Without understanding the Dao of Heaven and Earth, one cannot grasp this principle.

Water and Fire are manifestations of Yin and Yang, and alternative names for Heaven and Earth. Thus, it is said: "Solitary Yang does not generate; solitary Yin does not grow." The function of Heaven lies within the Earth, promoting the growth of all things; the function of Earth lies within Heaven, facilitating the storage of all things. This is the communication of all things through the interaction of Heaven and Earth, the way Heaven and Earth root each other. Therefore, the root of Yang Fire lies in the Earth, and the source of Yin Water lies in Heaven; hence, "Water flows from high sources." The Five Zang Organs govern tangible substances. Matter is Yin; Yin is Water. These are governed by the upper three pulse positions, predominantly visible at the Cun Kou (Radial Artery). Food blockage in the upper region severs the source of the Five Zang Organs. Once the source is severed, Water cannot flow downward, leading to the exhaustion of the Chi pulses. This is the logic; what is there to doubt?