滑石（六两） 甘草（一两）
暑月身热烦渴，水溺不利，主此方者，滑石性寒而淡，寒能清热，淡则利水，少佐甘草者，恐石性过寒，用
以和中尔。散名六一，非因方中铢两起见，盖取天一生水、地六成之之义，故河间又名天水散。本方加朱砂五钱，
名益元散，加薄荷名鸡苏散，加青黛名碧玉散，治同。本方加红曲五钱，饭丸名清六丸，治赤痢。加干姜名温六
丸，治白痢。本方加生柏叶、生藕节、生车前名三生益元饮。本方以吴茱萸代甘草，治湿热吞酸，名茱萸六一散。
以黄 代滑石，治盗汗消渴，名黄 六一散。以生石膏代滑石，名玉泉散，治阳明内热，烦渴头痛。
香薷 人参 橘皮 黄 白术 扁豆 甘草 浓朴 茯苓 木瓜
暑月身倦，神昏头重，吐利，目复欲作，此外感而兼内伤，当主是方。其义维何？暑能伤气，故身体倦怠，
神思昏沉，人参、黄 、木瓜以益之。暑为阳邪，并于上，故头重，目复欲作，浓朴、橘皮、香薷以散之。暑邪
干胃，必渴
而引饮。湿热相搏，故既吐且利，白术、茯苓、扁豆以安之。如此调理，病不除而目复能为害，未之前闻。
诗曰∶暑天却病尚香薷，扁豆参苓术亦宜，独怪瓜州甘氏子，浓煎陈橘饮黄 。
人参 白术 橘皮 黄 升麻 甘草 当归 麦冬 五味 干姜 葛根 青皮 苍术 神曲 泽泻 黄柏
长夏湿热炎蒸，神体倦怠不宁，身热气高，二便赤黄、渴而自汗，脉虚者，此方主之。
暑令行于长夏，则兼湿令矣，乃有上项诸症。故东垣处此方，兼而治之。盖五味、当归、麦冬、人参、黄 ，
所以宁神致液，而益既伤之气。二术、二皮、神曲、姜、草，所以调中破滞，而胜复伤之湿。余湿未除，清气不
升，葛根、升麻发而解之。余热未退，浊气不降，黄柏、泽泻导而泄之。
诗曰∶清暑益气补中得，外增苍术葛姜泽，麦冬五味雅相宜，去柴何取青曲柏。
酷暑烁肺金，兼湿又伤胃土，应神不宁，脉虚自汗。药用补中益气是也。且暑燥，滋以五味、麦冬；湿溽，
疏以曲、术、姜、葛，均合医理。外此他经无症，故出柴胡。知出柴胡，奈何以青皮、泽泻、黄柏克伐厥阴、太
阴，庭镜实不能解。是有诗之中末句云云。
Hua Shi (Talcum, 6 liang) Gan Cao (Licorice Root, 1 liang)
During the summer heat season, if there is body fever, irritability, thirst, and difficult urination, this formula is indicated. This is because Hua Shi (Talcum) is cold in nature and bland in taste; coldness clears heat, and blandness promotes diuresis. A small amount of Gan Cao (Licorice Root) is added to prevent the stone-like nature of Talcum from being excessively cold, thereby harmonizing the Stomach Qi. The name "Liu Yi San" (Six-to-One Powder) does not refer to the weight ratio of the ingredients in the formula, but rather derives from the principle of "Heaven generates Water with One, Earth completes it with Six." Therefore, Liu Hejian also called it Tian Shui San (Heavenly Water Powder). Adding five qian of Zhu Sha (Cinnabar) to this base formula creates Yi Yuan San (Benefit Origin Powder); adding Bo He (Mint Leaf) creates Ji Su San (Chicken-Su Powder); adding Qing Dai (Indigo Naturalis) creates Bi Yu San (Jade Green Powder); these share the same therapeutic effects. Adding five qian of Hong Qu (Red Yeast Rice) to this base formula and forming pills with rice yields Qing Liu Wan (Clear Six Pill), used for treating red dysentery. Adding Gan Jiang (Dried Ginger) yields Wen Liu Wan (Warm Six Pill), used for treating white dysentery. Adding Sheng Bai Ye (Fresh Cactus Leaf), Sheng Ou Jie (Lotus Node), and Sheng Che Qian (Plantago Seed/Herb) to this base formula yields San Sheng Yi Yuan Yin (Three Fresh Benefit Origin Decoction). Replacing Gan Cao (Licorice Root) with Wu Zhu Yu (Evodia Fruit) in this base formula, used for treating acid regurgitation due to damp-heat, is named Zhu Yu Liu Yi San (Evodia Six-to-One Powder). Replacing Hua Shi (Talcum) with Huang Qi (Astragalus Root) in this base formula, used for treating night sweats and Xiao Ke (Wasting-Thirst), is named Huang Qi Liu Yi San (Astragalus Six-to-One Powder). Replacing Hua Shi (Talcum) with Sheng Shi Gao (Gypsum Fibrosum) in this base formula, used for treating Yangming internal heat, irritability, thirst, and headache, is named Yu Quan San (Jade Spring Powder).
Xiang Ru (Mosla Herb) Ren Shen (Ginseng Root) Ju Pi (Citrus Peel) Huang Qi (Astragalus Root) Bai Zhu (Atractylodes Rhizome) Bian Dou (Lablab Bean) Gan Cao (Licorice Root) Hou Po (Magnolia Bark) Fu Ling (Poria) Mu Gua (Chaenomeles Fruit)
During the summer heat season, if there is body fatigue, mental confusion, heavy head, vomiting and diarrhea, and eyes swelling or impending pain, this indicates an external pathogenic invasion combined with internal injury. This formula should be indicated. What is the rationale? Summer heat can damage Qi, leading to body fatigue and mental confusion; Ren Shen (Ginseng Root), Huang Qi (Astragalus Root), and Mu Gua (Chaenomeles Fruit) are used to tonify this. Summer heat is a Yang pathogen that affects the upper body, causing heavy head and eye issues; Hou Po (Magnolia Bark), Ju Pi (Citrus Peel), and Xiang Ru (Mosla Herb) are used to disperse this. Summer heat pathogen interferes with the Stomach, inevitably causing thirst and desire to drink. Dampness and Heat struggle against each other, causing both vomiting and diarrhea; Bai Zhu (Atractylodes Rhizome), Fu Ling (Poria), and Bian Dou (Lablab Bean) are used to stabilize the Middle Jiao. With such regulation, it has never been heard of that the disease remains unremoved while eye swelling becomes harmful. The poem states: To dispel illness in summer, Xiang Ru (Mosla Herb) is preferred; Bian Dou (Lablab Bean), Ren Shen (Ginseng Root), Fu Ling (Poria), and Bai Zhu (Atractylodes Rhizome) are also suitable. It is strange that the descendant of the Gan family in Guazhou boils Chen Pi (Aged Tangerine Peel) thickly and drinks it with Huang Qi (Astragalus Root).
Ren Shen (Ginseng Root) Bai Zhu (Atractylodes Rhizome) Ju Pi (Citrus Peel) Huang Qi (Astragalus Root) Sheng Ma (Cimicifuga Rhizome) Gan Cao (Licorice Root) Dang Gui (Angelica Sinensis Root) Mai Dong (Ophiopogon Tuber) Wu Wei Zi (Schisandra Berry) Gan Jiang (Dried Ginger) Ge Gen (Kudzu Root) Qing Pi (Bitter Orange Peel) Cang Zhu (Atractylodes Lancea Rhizome) Shen Qu (Medicated Leaven) Ze Xie (Alisma Rhizome) Huang Bo (Phellodendron Bark)
In the late summer period, when damp-heat steams and roasts, causing spiritual and physical fatigue and restlessness, body fever, rapid breathing, reddish-yellow urine and stool, thirst, spontaneous sweating, and a deficient pulse, this formula is indicated.
When the Summer Heat command operates during late summer, it combines with the Dampness command, resulting in the aforementioned symptoms. Therefore, Li Dongyan prescribed this formula to treat them simultaneously. Wu Wei Zi (Schisandra Berry), Dang Gui (Angelica Sinensis Root), Mai Dong (Ophiopogon Tuber), Ren Shen (Ginseng Root), and Huang Qi (Astragalus Root) are used to calm the Spirit, generate fluids, and replenish the already damaged Qi. Cang Zhu (Atractylodes Lancea Rhizome), Bai Zhu (Atractylodes Rhizome), Qing Pi (Bitter Orange Peel), Ju Pi (Citrus Peel), Shen Qu (Medicated Leaven), Gan Jiang (Dried Ginger), and Gan Cao (Licorice Root) are used to regulate the Middle Jiao, break stagnation, and overcome the dampness that re-injures the body. If residual dampness remains and Clear Qi fails to ascend, Ge Gen (Kudzu Root) and Sheng Ma (Cimicifuga Rhizome) are used to diffuse and resolve it. If lingering heat remains and Turbid Qi fails to descend, Huang Bo (Phellodendron Bark) and Ze Xie (Alisma Rhizome) are used to guide and drain it.
The poem states: Clearing Summer Heat and Tonifying Qi aligns with tonifying the Middle; additionally using Cang Zhu (Atractylodes Lancea Rhizome), Ge Gen (Kudzu Root), Gan Jiang (Dried Ginger), and Ze Xie (Alisma Rhizome) is appropriate; Mai Dong (Ophiopogon Tuber) and Wu Wei Zi (Schisandra Berry) harmonize elegantly; why remove Chai Hu (Bupleurum Root) and instead take Qing Pi (Bitter Orange Peel), Shen Qu (Medicated Leaven), and Huang Bo (Phellodendron Bark)?
Intense summer heat scorches Lung Metal, and combined with dampness, injures Stomach Earth, leading to restless spirit and deficient spontaneous sweating. The medicinal use follows the principle of Bu Zhong Yi Qi Tang (Tonify the Middle and Augment the Qi Decoction). Since Summer Heat is drying, it is moistened with Wu Wei Zi (Schisandra Berry) and Mai Dong (Ophiopogon Tuber); since dampness is cloying, it is dispersed with Shen Qu (Medicated Leaven), Bai Zhu (Atractylodes Rhizome), Gan Jiang (Dried Ginger), and Ge Gen (Kudzu Root), all conforming to medical principles. As there are no symptoms in other meridians, Chai Hu (Bupleurum Root) is removed. Knowing that Chai Hu (Bupleurum Root) should be removed, how can one justify using Qing Pi (Bitter Orange Peel), Ze Xie (Alisma Rhizome), and Huang Bo (Phellodendron Bark) to attack the Jueyin Liver and Taiyin Spleen meridians? Huang Tingjing truly cannot understand this. This refers to the last two lines of the poem mentioned above.