治瘴病上盛下虚。痰涎壅塞。此药最能升降阴阳。镇坠阳气。安和五脏。扶助元气。水银（八两）
硫黄（二两） 上用新铁铫炒成砂有烟即以醋酒。候研细入水火鼎内。醋调赤石脂封口。铁线扎缚。
灯盏盐土固济。晒干用炭。二十斤。 炼如鼎裂。笔蘸赤石脂。频抹。火尽为度。经宿取出。研为细末。
糯米糊为丸。麻子大。每服二十丸。枣汤下。米饮人参任下。瘴病多因秋冬热则阳气外泄。浮而不降。下
元虚冷。是方用硫黄大热。能补下元真火。佐以水银至阴之物。复加 炼成水火既济之义。能祛拒
格之寒。兼有伏阳。大能降上焦之元气。于下元镇坠之。使不外泄。甚与瘴病为宜。
治外感风寒。内伤生冷。或五脏气虚。阴阳相胜。作为瘴疟。寒多热少。或但寒不
热。
大附子（一个炭火煨以盐浸再煨再浸七次去皮脐切片）
上用生姜七片。枣七枚。水煎。当发
早晨空心温服。仍吃枣三五枚。忌口为要。冷瘴因寒疾而作。是方用大附子去寒痰。且能引上焦之阳气。
下入至阴以成天地之交泰。正王太仆所谓益火之元。以消阴翳。加以大枣之甘。以温补脾气。则寒痰
息而瘴疟止矣。
治喜怒不节。饮食过度。劳役兼并。致阴阳相胜。结聚痰饮。与卫气相搏。发为瘴疟。
人参 半夏（汤泡七次） 茯苓（去皮） 白术 草果（去皮） 陈皮 甘草（炙减半） 乌梅（去核）
上 散用生姜枣子。入盐少许 之。食顷浓皮纸裹水蘸温。慢火煨香熟。焙干。每服半两。清水煎。
未发前连进三服。
瘴疟虽因天时。若平人脾胃元气实。则瘴毒虽惨。于身乎何有。惟喜怒伤气。饮食伤脾。则元气不固。
然后瘴毒得以干之。经所谓邪之所腠。其气必虚是也。是
方用参术苓草之甘温补脾。以益元气。加陈皮之辛。以理气。半夏之辛。以燥湿利痰。草果之辛。
以消食。乌梅之酸。以敛气生津。姜枣以补元气。共为截疟之方。亦君子满座。小人自退之意也。
治疗瘴病中上实下虚之证。痰涎壅盛阻塞气道。此药最能调节阴阳升降。镇摄浮越之阳气。调和五脏。扶助元气。水银（八两）硫黄（二两）。以上药材用新铁锅炒至成砂状且有烟冒出时，立即加入醋和酒。待研磨细后放入水火鼎内。用醋调赤石脂封口。用铁线捆扎固定。用灯盏盐土加固密封。晒干后用炭火煅烧二十斤重。煅烧至鼎身出现裂纹时，用笔蘸取赤石脂浆液频繁涂抹裂缝处。直至火候燃尽为止。过夜后取出。研磨成细末。用糯米糊制作成丸剂。大小如麻子。每次服用二十丸。用枣汤送服。也可用米饮或人参汤送服。瘴病多因秋冬季节气候反常发热，导致阳气外泄。阳气浮越而不能下降。下元虚冷。本方使用大热的硫黄。能补益下元真火。佐以属至阴的水银。再加上经过炼制体现“水火既济”的含义。能祛除格拒之寒邪。兼治伏阳。大能降逆上焦之元气。在下元处加以镇摄。使其不外泄。非常适宜于治疗瘴病。
治疗外感风寒。内伤生冷食物。或五脏气虚。阴阳相互偏胜。从而形成瘴疟。表现为恶寒多而发热少。或者只有寒冷而没有发热。
大附子（一个。用炭火煨烤，用盐水浸泡，再煨烤再浸泡，重复七次。去皮去脐，切片）
以上药材加生姜七片。大枣七枚。加水煎煮。在发病当天的早晨空腹温服。服药后仍吃三到五枚大枣。忌口非常重要。冷瘴因寒性疾病发作。本方使用大附子去除寒痰。且能引导上焦的阳气。下行进入至阴之地以达成天地交泰的状态。正是王冰所谓“益火之源，以消阴翳”的意思。加上大枣的甘味。来温补脾气。则寒痰平息而瘴疟停止。
治疗喜怒没有节制。饮食过度。劳累与房事兼并。导致阴阳相互偏胜。结聚痰饮。与卫气相搏结。发作成为瘴疟。
人参 半夏（用汤泡七次） 茯苓（去皮） 白术 草果（去皮） 陈皮 甘草（炙过，减半用量） 乌梅（去核）
以上药材制成散剂。食用时用生姜大枣。加入少许盐。食顷时间后，用浓皮纸包裹，蘸水湿润。用慢火煨烤至香熟。焙干。每次服用半两。用清水煎煮。
在疾病未发作前连续服用三次。
瘴疟虽然因天时气候引起。但如果普通人脾胃元气充实。那么即使瘴毒猛烈。对身体又能有什么损害呢？只有喜怒伤气。饮食伤脾。导致元气不固。然后瘴毒才能侵犯人体。经书所说“邪之所凑，其气必虚”就是这个道理。本方用人参、白术、茯苓、甘草的甘温之性补脾。以益元气。加上陈皮的辛味。以理气。半夏的辛味。以燥湿利痰。草果的辛味。以消食。乌梅的酸味。以收敛气生津。姜枣以补元气。共同组成截断疟疾的方剂。也蕴含君子正气充足。小人自然退避的意思。
Treats the syndrome of miasma malaria characterized by excess in the upper body and deficiency in the lower body. With phlegm-fluids obstructing and blocking the airways, this medicine is most capable of regulating the ascending and descending of Yin and Yang, suppressing floating Yang Qi, harmonizing the Five Zang Organs, and supporting Yuan Qi (Primordial Qi). Mercury (8 liang), Sulfur (2 liang). Take the above herbs and stir-fry them in a new iron pot until they turn into sand with smoke rising. Immediately add vinegar and wine. After grinding finely, place them into a "Water-Fire Cauldron" (a specialized fuming vessel). Seal the mouth with red stone powder mixed with vinegar. Bind tightly with iron wire. Reinforce the seal with salt earth from a lamp holder. Dry in the sun. Use charcoal for calcination weighing twenty jin. Calcine until cracks appear on the cauldron. Use a brush dipped in red stone powder paste to frequently smear the cracks. Continue until the fire burns out completely. Remove after overnight. Grind into fine powder. Form pills using rice flour paste, sized like hemp seeds. Take 20 pills per dose. Administer with Jujube Decoction. Alternatively, administer with Rice Drink or Ginseng Decoction. Miasma malaria often occurs due to abnormal heat in autumn and winter seasons, causing Yang Qi to leak outward. The Yang Qi floats and fails to descend, while the Lower Origin (Kidney system) is deficient and cold. This formula uses the intensely hot Sulfur to tonify the True Fire of the Lower Origin. It assists with Mercury, a substance of extreme Yin nature, combined with the refined meaning of "Water and Fire having achieved harmony." It can expel cold that causes rejection and blockage, and also addresses hidden Yang. It greatly descends the Yuan Qi of the Upper Jiao and suppresses it at the Lower Origin, preventing it from leaking outward. It is highly suitable for treating miasma malaria.
Treats external contraction of Wind-Cold, internal injury from raw and cold foods, or deficiency of Qi in the Five Zang Organs, where Yin and Yang contend with each other, resulting in miasma malaria. Manifestations include more chills than fever, or only chills without fever.
Large Aconite Root (one piece. Roasted over charcoal fire, soaked in salt water, roasted again and soaked again, repeated seven times. Peel off skin and remove umbilical scar, slice).
Take the above herb, add seven slices of Fresh Ginger and seven dates. Decoct in water. Take warm on an empty stomach on the morning when the attack is due. Still eat three to five dates afterwards. Observing dietary restrictions is essential. Cold miasma arises from cold pathogens. This formula uses Large Aconite Root to dispel cold-phlegm and guide the Yang Qi of the Upper Jiao downward into the extreme Yin to achieve the interaction between Heaven and Earth. This aligns with Wang Bing's saying: "Tonify the source of Fire to dissipate Yin shadows." Adding the sweetness of Jujube to warm and tonify Spleen Qi, the cold-phlegm subsides and miasma malaria ceases.
Treats irregularity in emotions (anger and joy), excessive diet, and combined labor and sexual exertion, leading to contention between Yin and Yang, accumulation of phlegm-fluids, which contend with Defensive Qi, manifesting as miasma malaria.
Ginseng Root, Pinellia Tuber (soaked in boiling water seven times), Poria, Atractylodes Rhizome, Tsaoko Fruit (peeled), Tangerine Peel, Licorice Root (roasted, halved dosage), Mume Fruit (pitted).
Process the above into a powder. When taking, use Fresh Ginger and Jujube. Add a little salt. After a meal period, wrap in thick paper, moisten with water. Slow-roast until fragrant and cooked. Dry thoroughly. Take half a liang per dose. Decoct in clear water. Take three doses consecutively before the onset of the disease.
Although miasma malaria is caused by climatic factors, if a normal person has substantial Spleen and Stomach Yuan Qi, even severe miasma toxins will have no effect on the body. Only when anger injures Qi and diet injures the Spleen, causing Yuan Qi to be insecure, can the miasma toxin invade. As stated in the Classics: "Where pathogenic factors gather, the Qi must be deficient." This formula uses the sweet and warm properties of Ginseng, Atractylodes, Poria, and Licorice to tonify the Spleen and benefit Yuan Qi. It adds the pungency of Tangerine Peel to regulate Qi, the pungency of Pinellia to dry dampness and promote phlegm resolution, the pungency of Tsaoko to digest food, and the sourness of Mume Fruit to astringe Qi and generate fluids. Ginger and Jujube tonify Yuan Qi. Together, they form a formula to intercept malaria, embodying the principle that when the gentleman (righteous Qi) fills the room, the petty man (pathogen) naturally retreats.