集说∶囟填者，囟门肿起也。脾主肌肉，乳食不常，饥饱无度，或寒或热，乘于脾家，
致使
上冲
热交
地黄丸
治年大小儿头缝开解不合。肾主髓，脑为髓海，肾气有亏，脑髓不足，所以脑颅开
能合。凡脑髓欠少，如木无根，不过千日，终成废人。
大熟地黄（洗焙，四钱） 山茱萸 干山药（各二钱） 泽泻（一钱） 牡丹皮 白茯
苓（各
一钱
上为末，烂蜜丸，梧桐子大。每服一二丸，温水，空心送下。仍用大南星微炮，为末，
米醋
三辛散
治头骨应合不合，头骨开解，名曰解颅。
细辛 桂心（各半两） 干姜（七钱半）
上为末，以乳汁和敷颅上，干复敷之，儿面赤即愈。
又方
蛇蜕炒焦为末，用猪颊车中髓调敷顶上，日三四度。有人作头巾裹遮护之，久而自合
，亦良法也。
又方
驴头骨不以多少，烧灰研细，以清油调敷头缝中。
薏苡丸
治所受肝气虚弱，致两脉挛缩，两手伸展无力。
当归（焙干） 秦艽 薏苡仁 酸枣仁 防风 羌活（各一两）
上为末，炼蜜丸，鸡头大。每一粒到二粒，麝香、荆芥汤化下。
海桐皮散
治禀受肾气不足，血气未荣，脚指拳缩无力，不能伸展。
海桐皮 牡丹皮 当归 熟地黄 牛膝（各一两） 山茱萸 补骨脂（各半两）
上为末。每服一钱，葱白二寸煎，食前服。
[Collected Explanations] Xintian (Fontanelle Distension) refers to the swelling and protrusion of the fontanelle. The Spleen governs muscles; if breastfeeding or feeding is irregular, with no regularity in hunger and fullness, or if affected by Cold or Heat pathogens invading the Spleen system, causing Heat to rush upward and intertwine.
Dihuang Wan (Rehmannia Pill): Treats infants and children of all ages whose cranial sutures are open and fail to close. The Kidney governs Marrow, and the Brain is the Sea of Marrow. If Kidney Qi is deficient and Brain Marrow is insufficient, the cranial sutures remain open and cannot heal. Whenever Brain Marrow is lacking, it is like a tree without roots; within a thousand days, one will ultimately become disabled.
Da Shu Dihuang (Prepared Rehmanniae Radix, washed and dried, 4 qian), Shanzhuyu (Corni Fructus), Gan Shanyao (Dried Dioscoreae Rhizoma, each 2 qian), Zexie (Alismatis Rhizoma, 1 qian), Mudanpi (Moutan Cortex), Bai Fuling (Poria, each 1 qian).
Grind the above into powder, mix with refined honey to form pills the size of Sophora seeds. Take 1-2 pills per dose, swallowed with warm water on an empty stomach. Additionally, use large Tianxing (Arisaema Cum Bile) slightly roasted and ground into powder, mixed with rice vinegar for external application.
Sanxin San (Three Acrids Powder): Treats cases where the skull should have closed but remains open, known as Jielu (Delayed Closure of Fontanelle).
Xixin (Asari Radix et Rhizoma), Guixin (Cinnamomi Ramulus, each 0.5 liang), Ganjiang (Zingiberis Rhizoma, 7.5 qian).
Grind the above into powder, mix with breast milk for topical application on the cranium. Reapply when dry; healing occurs when the infant's face becomes ruddy.
Another Prescription:
Burn snake slough until charred, grind into powder, and mix with marrow from the pig's mandible to apply on the vertex. Apply 3-4 times daily. Some people wrap the head with a cloth to protect it; over time, it closes naturally, which is also an effective method.
Another Prescription:
Donkey skull bone, quantity unspecified, burn to ash, grind finely, and mix with clarified sesame oil to apply into the cranial suture.
Yiyi Wan (Coix Seed Pill): Treats weakness of inherited Liver Qi, leading to contraction of two meridians and weakness in extending the hands.
Danggui (Angelicae Sinensis Radix, dried by baking), Qinjiao (Gentianae Macrophyllae Radix), Yiyiren (Coicis Semen), Suanzao Ren (Ziziphi Spinosae Semen), Fangfeng (Saposhnikoviae Radix), Qianghuo (Notopterygii Rhizoma et Radix, each 1 liang).
Grind the above into powder, mix with refined honey to form pills the size of a corn kernel. Take 1-2 pills per dose, dissolved and taken with decoction of Shexiang (Moschus) and Jingjie (Schizonepetae Herba).
Haitongpi San (Tsoo Bark Powder): Treats insufficiency of inherited Kidney Qi, where Blood and Qi fail to flourish and nourish, resulting in curled toes with weakness and inability to extend.
Haitongpi (Formosanae Lonicerae Caulis), Mudanpi (Moutan Cortex), Danggui (Angelicae Sinensis Radix), Shu Dihuang (Prepared Rehmanniae Radix), Niuxi (Achyranthis Bidentatae Radix, each 1 liang), Shanzhuyu (Corni Fructus), Buguzhi (Psoraleae Fructus, each 0.5 liang).
Grind the above into powder. Take 1 qian per dose, decocted with 2 cun of Congbai (Allii Fistulosi Bulbus), taken before meals.