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Cases of Huoluan (cholera-like syndrome with sudden vomiting and diarrhea) that arise at the beginning of the disease indicate that cold pathogenic factors have injured the interior. If the pathology is in the Upper Jiao (Upper Burner), it manifests as vomiting; if in the Lower Jiao (Lower Burner), as diarrhea; and if in the Middle Jiao (Middle Burner), both vomiting and diarrhea occur. If, after vomiting and diarrhea, the symptoms of Shanghan (Cold Damage) do not resolve, the condition will inevitably relapse into further vomiting and diarrhea due to the weakness of the Spleen and Stomach. This constitutes a severe deficiency and is a critical prognosis.

Furthermore, there are cases where there is neither vomiting nor diarrhea, but rather a sudden onset of mild abdominal pain that gradually worsens, accompanied by loss of consciousness. This is named Gan Huoluan (Dry Cholera), commonly known in folk medicine as Sha Qi (Sha Gas). In practice, some people scrape the skin on the side of the thighs or behind the neck until petechiae appear, a method called Gua Sha (Scraping Therapy); or they prick the visible veins in the popliteal fossa (back of the knee) to release blood, a method called Fang Sha (Bloodletting for Sha). The underlying principle is that the Spleen governs the four limbs and guides the Qi of the four extremities to disseminate and unblock the stagnation within the Spleen system. Zhu Danxi stated: "Releasing blood via Fang Sha depletes Qi, whereas Gua Sha promotes the circulation of Qi and Blood more effectively." One must also avoid consuming grains and hot-natured foods.

Although urination and defecation exit through the Large Intestine and Small Intestine respectively, both belong to Yin and are connected to the opening and closing of the Kidneys. Some cases result from excessive sweating leading to the loss of Yin fluids, where heat consumes body fluids, causing urinary retention and dry, hard stools. Others result from heat accumulation in both intestines, preventing fluid distribution and trapping heat without an outlet. Consequently, symptoms such as delirium, mania, and jaundice may follow. For constipation due to Blood deficiency, moistening agents should be used to unblock the bowels; for constipation due to heat accumulation, bitter-cold purgatives should be used to drain the heat.

The disease of panting (Chuan) is numerous, but fundamentally stems from the rebellious upward movement of Lung Qi. If panting occurs before sweating, it indicates the pathogen is in the Exterior with obstructed Qi flow, requiring treatment with methods that release the muscle layer (Jie Ji). If panting follows fright, it requires calming the Heart and anchoring the Spirit. If panting is accompanied by phlegm obstruction and abdominal fullness, it requires purging accumulated phlegm and stagnation. If panting accompanies the eruption of rashes, it requires promoting the outward expulsion of pathogens. If panting is due to retained fluid, it requires dispersing water-dampness. However, if the patient presents with fixed staring, irritability, chest fullness, coarse breathing, sweat like oil, and incessant panting, this is a sign of a deteriorated condition (Huai Zheng).

Yinuria (Weyu) refers to involuntary urination without the patient's awareness. Generally, Yinuria caused by intense heat leading to clouded consciousness is treatable. However, Yinuria occurring in Yin syndromes with lower jiao coldness, cold extremities, and a deep, slow pulse indicating impending collapse is considered untreatable. In such cases, Sini Tang (Frigid Extremities Decoction) added with Yizhi Ren (Alpinia Oxyphylla Fruit) should be administered. For Ju Yin (Liver Meridian) conditions presenting with testicular retraction, cold extremities, deep pulse, and Yinuria, Si Wu Jia Zhuyu Tang (Four Substances plus Cornus Decoction) is indicated. If Yang Qi fails to return, death ensues. After sweating or purging therapies, if heat persists and Yin deficiency leads to deficient fire disturbing the bladder causing Yinuria, Renshen Sanbai Tang (Ginseng Three Whites Decoction) added with Huangbai (Phellodendron Bark), Zhimu (Anemarrhena Rhizome), Maidong (Ophiopogon Tuber), Wuweizi (Schisandra Berry), and Danggui (Angelica Sinensis Root) should be used.