夫伤寒六日。足厥阴受病。厥阴者肝之经也。其脉循阴。络于肝。故得病六日。烦满而
阴缩也。此则阴阳俱受病。毒瓦斯在胃。故可下而愈也。
治伤寒病六日。其病深结在脏。是三阴三阳俱受病。若五脏六腑荣卫皆不通。其
人难治
柴胡（二两去苗） 黄芩（一两） 赤芍药（一两） 半夏（半两汤洗七遍去滑） 枳
实（半两
麸炒微黄） 人参〔一（二）两去芦头〕 甘草（半两炙微赤锉）
上件药。捣筛为散。每服四钱。以水一中盏。入生姜半分。煎至六分。去滓。不计时候
温服。
治伤寒六日。体重。四肢烦疼。多渴。或谵语不知人事。如此病证者。胃中有结燥
。宜
川大黄（二两锉碎微炒） 枳实（二两麸炒微黄） 川朴硝（二两） 浓朴（一两去粗
皮涂生
姜汁炙令香熟）
上件药。粗捣罗为散。每服四钱。用水一中盏。煎至六分。去滓。不计时候温服。以利
为度。如人行十里未利。再服。
治伤寒六日。心胸妨闷。烦热不解。面赤大渴。壮热。身体疼痛。此证是毒瓦斯攻心
。宜
半夏（半两汤洗七遍去滑） 人参（半两去芦头） 木通（一两锉） 甘草（一两炙微
赤锉）
黄芩（一两） 川大黄（一两锉碎微炒）
上件药。粗捣罗为散。每服四钱。以水一中盏。入生姜半分。枣三枚。煎至六分。去滓
。不计时候温服。
治伤寒六日。呕哕不定。头痛体疼。时有虚汗。此证是冷热未和。宜服人参散方。
人参（二两去芦头） 柴胡（二两去苗） 黄芩（一两） 甘草（一两炙微赤锉） 白
术（一两）
半夏（半两汤洗七遍去滑） 浓朴（一两去粗皮涂生姜汁炙令香熟）
上件药。捣粗罗为散。每服三钱。以水一中盏。入生姜半分。枣三枚。煎至六分。去滓
。不计时候温服。
治伤寒六日。发汗不解。呕逆。小便不利。胸胁痞满。微热而烦。黄芩汤方。
黄芩（一两） 桂心（一两） 赤茯苓（一两） 前胡（二两去芦头） 半夏（一两汤
洗七遍去
滑） 甘草（半两炙微赤锉） 浓朴（二两去粗皮涂生姜汁炙令香熟）
上件药。粗捣罗为散。每服三钱。以水一大盏。入生姜半分。枣三枚。煎至五分。去滓
。不计时候温服。
治伤寒六日。发热恶寒。（四）肢节疼痛。微呕。心下痞结。外证未去。柴胡桂枝
汤方。
桂枝（一两） 柴胡（二两去苗） 芎 （二两） 人参（一两去芦头） 黄芩（一两）
赤芍药
（一两） 枳壳（一两麸炒微黄去瓤） 甘草（半两炙微赤锉） 半夏（一两汤洗七遍去滑）
上件药。捣筛为散。每服五钱。以水一大盏。入生姜半分。枣三枚。煎至五分。去滓。
不计时候温服。
治伤寒六日。其人已发汗而不解。胸胁满。小便不多利。渴而不呕。但头汗出。
往来寒
牡蛎（一两烧为粉） 甘草（一两炙微赤锉） 干姜〔一（半）两炮裂锉〕 柴胡（二
两去苗）
木通
生姜汁炙
令香熟
上件药。捣筛为散。每服三钱。以水一中盏。煎至五分。去滓。不计时候温服。
治伤寒六日。吐泻。百骨疼痛。脚冷腹热。宜服人参散方。
人参（三分去芦头） 柴胡（三分去苗） 白茯苓（三分） 牡蛎（三分烧为粉） 黄
芩（三分）
白
姜（三
分炮
上件药。捣筛为散。每服三钱。以水一中盏。入生姜半分。枣三枚。煎至五分。去滓。
不计时候温服。
治伤寒六日。发热烦闷。渴欲饮水。得水而吐。其脉浮数。小便不利者。宜服猪
苓汤方
猪苓（三分去黑皮） 白术（三分） 泽泻（一两） 桂心（半两） 赤茯苓（三分） 丁
香（三
分） 甘草（三分炙微赤锉） 浓朴（一两半去粗皮涂生姜汁炙令香熟）
上件药。捣粗罗为散。每服三钱。以水一中盏。入生姜半分。煎至五分。去滓。不计时
候温服。
治伤寒六日。心躁烦渴。肢节解痛。小腹急满阴缩。宜服葛根散方。
葛根（三分锉） 石膏（一两） 柴胡（一两去苗） 川升麻（三分） 知母（三分） 栀
子仁（
半两） 甘草（三分炙微赤锉） 川大黄（一两锉碎微炒）
上件药。捣筛为散。每服一（四）钱。以水一中盏。入生姜半分。煎至六分。去滓。
不计
时候温服。
治伤寒六日。心躁烦闷。四肢疼痛。小腹满急。宜服大青散方。
大青（三分） 柴胡（一两去苗） 栀子仁（一分） 川升麻（三分） 知母（三分） 石
膏（一
两） 甘草（三分炙微赤锉）
上件药。捣筛为散。每服四钱。以水一中盏。入生姜半分。煎至六分。去滓。不计时候
温服。
治伤寒六日。脉沉细不足者。宜服通关散方。
附子（一两炮裂去皮脐） 干姜〔五（半）两炮裂锉〕 甘草（半两炙微赤锉） 黄
（三分
锉） 桔梗（半两去芦头） 防风（三分去芦头） 羌活（半两） 五加皮（半两） 桂心
（三分）
上件药。捣筛为散。每服三钱。以水一中盏。煎至六分。去滓。不计时候温服。
治伤寒六日。头痛壮热。百节疼痛。宜服柴胡散方。
柴胡（一两去苗） 川升麻（三分） 黄芩（三分） 知母（一两） 赤芍药（一两） 大
青（三
分）
双仁麸炒
微黄
上件药。捣筛为散。每服四钱。以水一中盏。入生姜半分。豉五十粒。煎至六分。去滓
。不计时候温服。
治伤寒六日。热在脏。胸中烦闷。口噤不能言。唯欲饮水。成坏伤寒。医所不疗
\x。宜服
麻黄〔三分（两）去根节〕 灶下黄土（二两） 川大黄（二两） 黄芩（二两） 川
芒硝（二
两） 灶突墨（二两） 梁上尘（二两）
上件药。捣罗为末。炼蜜和丸。如弹子大。每服。不计时候。以井华水研下一丸。
When cold damage (Shanghan) progresses to the sixth day, the Foot Jueyin Meridian is affected. The Jueyin Meridian is the channel of the Liver. Its pulse circulates along the yin regions and connects with the Liver. Therefore, after six days of illness, symptoms such as mental restlessness and fullness, along with contraction of the genitals, may occur. This indicates that both yin and yang meridians are affected, and toxic heat is accumulated in the Stomach. Thus, purgation can be used to achieve a cure.
In treating cold damage on the sixth day, if the pathogen has deeply settled in the zang-fu organs, affecting all three yin and three yang meridians, and if the qi and blood of the five zang and six fu organs, as well as Ying and Wei, are completely blocked, the patient is difficult to treat.
Chai Hu (Radix Bupleuri, 2 liang, remove seedlings), Huang Qin (Radix Scutellariae, 1 liang), Chi Shao Yao (Radix Paeoniae Rubra, 1 liang), Ban Xia (Rhizoma Pinelliae, 0.5 liang, wash seven times in decoction to remove slipperiness), Zhi Shi (Fructus Aurantii Immaturus, 0.5 liang, stir-bran-fried until slightly yellow), Ren Shen (Radix Ginseng, 1 or 2 liang, remove rhizome), Gan Cao (Radix Glycyrrhizae, 0.5 liang, honey-fried until slightly red, cut into pieces).
Crush and sieve the above ingredients to make a powder. Take 4 qian per dose. Add one zhong zhan of water and half a fen of fresh ginger. Decoct until six parts remain. Strain. Take warm at any time.
For cold damage on the sixth day, where the disease is deep-seated in the viscera, involving all three yin and three yang meridians, and if the circulation of nutritive and defensive qi in the five zang and six fu organs is obstructed, the prognosis is poor.
Chuan Da Huang (Radix et Rhizoma Rhei, 2 liang, cut into pieces and lightly stir-fried), Zhi Shi (Fructus Aurantii Immaturus, 2 liang, stir-bran-fried until slightly yellow), Chuan Po Xiao (Natrii Sulfas, 2 liang), Nong Po (Cortex Magnoliae Officinalis, 1 liang, remove rough bark, coat with fresh ginger juice, fry until fragrant).
Coarsely crush and sieve the above ingredients to make a powder. Take 4 qian per dose. Add one zhong zhan of water. Decoct until six parts remain. Strain. Take warm at any time. Use bowel movement as the criterion for efficacy. If no bowel movement occurs after walking ten li, administer another dose.
For cold damage on the sixth day, characterized by chest and epigastric oppression, unresolved irritability and heat, flushed face, extreme thirst, high fever, and body pain, indicating toxic heat attacking the Heart:
Ban Xia (Rhizoma Pinelliae, 0.5 liang, wash seven times in decoction to remove slipperiness), Ren Shen (Radix Ginseng, 0.5 liang, remove rhizome), Mu Tong (Caulis Akebiae, 1 liang, cut into pieces), Gan Cao (Radix Glycyrrhizae, 1 liang, honey-fried until slightly red, cut into pieces), Huang Qin (Radix Scutellariae, 1 liang), Chuan Da Huang (Radix et Rhizoma Rhei, 1 liang, cut into pieces and lightly stir-fried).
Coarsely crush and sieve the above ingredients to make a powder. Take 4 qian per dose. Add one zhong zhan of water, half a fen of fresh ginger, and three jujubes. Decoct until six parts remain. Strain. Take warm at any time.
For cold damage on the sixth day, with irregular vomiting and hiccups, headache, body pain, and occasional spontaneous sweating, indicating an imbalance between cold and heat:
Ren Shen (Radix Ginseng, 2 liang, remove rhizome), Chai Hu (Radix Bupleuri, 2 liang, remove seedlings), Huang Qin (Radix Scutellariae, 1 liang), Gan Cao (Radix Glycyrrhizae, 1 liang, honey-fried until slightly red, cut into pieces), Bai Zhu (Radix Atractylodis Macrocephalae, 1 liang), Ban Xia (Rhizoma Pinelliae, 0.5 liang, wash seven times in decoction to remove slipperiness), Nong Po (Cortex Magnoliae Officinalis, 1 liang, remove rough bark, coat with fresh ginger juice, fry until fragrant).
Coarsely crush and sieve the above ingredients to make a powder. Take 3 qian per dose. Add one zhong zhan of water, half a fen of fresh ginger, and three jujubes. Decoct until six parts remain. Strain. Take warm at any time.
For cold damage on the sixth day, where sweating fails to resolve the condition, accompanied by regurgitation, dysuria, hypochondriac fullness, slight fever, and irritability:
Huang Qin (Radix Scutellariae, 1 liang), Gui Xin (Cortex Cinnamomi, 1 liang), Chi Fu Ling (Poria with Red Core, 1 liang), Qian Hu (Radix Peucedani, 2 liang, remove rhizome), Ban Xia (Rhizoma Pinelliae, 1 liang, wash seven times in decoction to remove slipperiness), Gan Cao (Radix Glycyrrhizae, 0.5 liang, honey-fried until slightly red, cut into pieces), Nong Po (Cortex Magnoliae Officinalis, 2 liang, remove rough bark, coat with fresh ginger juice, fry until fragrant).
Coarsely crush and sieve the above ingredients to make a powder. Take 3 qian per dose. Add one da zhan of water, half a fen of fresh ginger, and three jujubes. Decoct until five parts remain. Strain. Take warm at any time.
For cold damage on the sixth day, presenting with fever, aversion to cold, pain in the four limbs and joints, slight vomiting, epigastric stuffiness, and unresolving exterior syndrome:
Gui Zhi (Ramulus Cinnamomi, 1 liang), Chai Hu (Radix Bupleuri, 2 liang, remove seedlings), Xiong Duan (Radix Ligustici Chuanxiong, 2 liang), Ren Shen (Radix Ginseng, 1 liang, remove rhizome), Huang Qin (Radix Scutellariae, 1 liang), Chi Shao Yao (Radix Paeoniae Rubra, 1 liang), Zhi Ke (Pericarpium Citri Reticulatae, 1 liang, stir-bran-fried until slightly yellow, remove pith), Gan Cao (Radix Glycyrrhizae, 0.5 liang, honey-fried until slightly red, cut into pieces), Ban Xia (Rhizoma Pinelliae, 1 liang, wash seven times in decoction to remove slipperiness).
Crush and sieve the above ingredients to make a powder. Take 5 qian per dose. Add one da zhan of water, half a fen of fresh ginger, and three jujubes. Decoct until five parts remain. Strain. Take warm at any time.
For cold damage on the sixth day, where sweating has been applied but the disease persists, with chest and hypochondriac fullness, scanty urination, thirst without vomiting, only sweating on the head, and alternating chills and fever:
Mu Li (Concha Ostreae, 1 liang, calcined to powder), Gan Cao (Radix Glycyrrhizae, 1 liang, honey-fried until slightly red, cut into pieces), Gan Jiang (Rhizoma Zingiberis Recens, 1 or 0.5 liang, processed until cracked, cut into pieces), Chai Hu (Radix Bupleuri, 2 liang, remove seedlings), Mu Tong (Caulis Akebiae). [Note: Text fragment "stir-fried with fresh ginger juice until fragrant" appears misplaced].
Crush and sieve the above ingredients to make a powder. Take 3 qian per dose. Add one zhong zhan of water. Decoct until five parts remain. Strain. Take warm at any time.
For cold damage on the sixth day, with vomiting and diarrhea, severe bone pain, cold feet and hot abdomen:
Ren Shen (Radix Ginseng, 3 fen, remove rhizome), Chai Hu (Radix Bupleuri, 3 fen, remove seedlings), Bai Fu Ling (Poria, 3 fen), Mu Li (Concha Ostreae, 3 fen, calcined to powder), Huang Qin (Radix Scutellariae, 3 fen), Bai Jiang (Processed Ginger, 3 fen, processed).
Crush and sieve the above ingredients to make a powder. Take 3 qian per dose. Add one zhong zhan of water, half a fen of fresh ginger, and three jujubes. Decoct until five parts remain. Strain. Take warm at any time.
For cold damage on the sixth day, with fever, irritability, thirst for water, vomiting after drinking, floating and rapid pulse, and dysuria:
Zhu Ling (Sclerotium Polypori, 3 fen, remove black skin), Bai Zhu (Radix Atractylodis Macrocephalae, 3 fen), Ze Xie (Rhizoma Alismatis, 1 liang), Gui Xin (Cortex Cinnamomi, 0.5 liang), Chi Fu Ling (Poria with Red Core, 3 fen), Ding Xiang (Flos Caryophylli, 3 fen), Gan Cao (Radix Glycyrrhizae, 3 fen, honey-fried until slightly red, cut into pieces), Nong Po (Cortex Magnoliae Officinalis, 1.5 liang, remove rough bark, coat with fresh ginger juice, fry until fragrant).
Coarsely crush and sieve the above ingredients to make a powder. Take 3 qian per dose. Add one zhong zhan of water, half a fen of fresh ginger. Decoct until five parts remain. Strain. Take warm at any time.
For cold damage on the sixth day, with mental restlessness, irritability, thirst, limb joint pain, lower abdominal urgency and fullness, and genital contraction:
Ge Gen (Radix Puerariae Lobatae, 3 fen, cut into pieces), Shi Gao (Gypsum Fibrosum, 1 liang), Chai Hu (Radix Bupleuri, 1 liang, remove seedlings), Chuan Sheng Ma (Radix Cimicifugae, 3 fen), Zhi Mu (Rhizoma Anemarrhenae, 3 fen), Zhi Zi Ren (Semen Gossypii Herbaceae, 0.5 liang), Gan Cao (Radix Glycyrrhizae, 3 fen, honey-fried until slightly red, cut into pieces), Chuan Da Huang (Radix et Rhizoma Rhei, 1 liang, cut into pieces and lightly stir-fried).
Crush and sieve the above ingredients to make a powder. Take 1 or 4 qian per dose. Add one zhong zhan of water, half a fen of fresh ginger. Decoct until six parts remain. Strain. Take warm at any time.
For cold damage on the sixth day, with mental restlessness, irritability, limb pain, and lower abdominal fullness and urgency:
Da Qing (Folium Isatidis, 3 fen), Chai Hu (Radix Bupleuri, 1 liang, remove seedlings), Zhi Zi Ren (Semen Gossypii Herbaceae, 1 fen), Chuan Sheng Ma (Radix Cimicifugae, 3 fen), Zhi Mu (Rhizoma Anemarrhenae, 3 fen), Shi Gao (Gypsum Fibrosum, 1 liang), Gan Cao (Radix Glycyrrhizae, 3 fen, honey-fried until slightly red, cut into pieces).
Crush and sieve the above ingredients to make a powder. Take 4 qian per dose. Add one zhong zhan of water, half a fen of fresh ginger. Decoct until six parts remain. Strain. Take warm at any time.
For cold damage on the sixth day, with sinking, fine, and deficient pulse:
Fu Zi (Radix Aconiti Lateralis Preparata, 1 liang, processed until cracked, remove skin and rootlets), Gan Jiang (Rhizoma Zingiberis Recens, 5 or 0.5 liang, processed until cracked, cut into pieces), Gan Cao (Radix Glycyrrhizae, 0.5 liang, honey-fried until slightly red, cut into pieces), Huang Qi (Radix Astragali, 3 fen, cut into pieces), Jie Geng (Radix Platycodi, 0.5 liang, remove rhizome), Fang Feng (Radix Saposhnikoviae, 3 fen, remove rhizome), Qiang Huo (Rhizoma et Radix Notopterygii, 0.5 liang), Wu Jia Pi (Cortex Acanthopanacis, 0.5 liang), Gui Xin (Cortex Cinnamomi, 3 fen).
Crush and sieve the above ingredients to make a powder. Take 3 qian per dose. Add one zhong zhan of water. Decoct until six parts remain. Strain. Take warm at any time.
For cold damage on the sixth day, with headache, high fever, and severe joint pain:
Chai Hu (Radix Bupleuri, 1 liang, remove seedlings), Chuan Sheng Ma (Radix Cimicifugae, 3 fen), Huang Qin (Radix Scutellariae, 3 fen), Zhi Mu (Rhizoma Anemarrhenae, 1 liang), Chi Shao Yao (Radix Paeoniae Rubra, 1 liang), Da Qing (Folium Isatidis, 3 fen), Xing Ren (Semen Armeniacae Amarum, double kernel, stir-bran-fried until slightly yellow).
Crush and sieve the above ingredients to make a powder. Take 4 qian per dose. Add one zhong zhan of water, half a fen of fresh ginger, and 50 grains of Dou Chi (Fermented Soybean). Decoct until six parts remain. Strain. Take warm at any time.
For cold damage on the sixth day, with heat in the zang organs, chest stuffiness, trismus preventing speech, desire only for water, representing a complicated cold damage difficult to treat by physicians:
Ma Huang (Herba Ephedrae, 3 or 3 liang, remove roots and joints), Zao Xia Huang Tu (Yellow Earth from under the stove, 2 liang), Chuan Da Huang (Radix et Rhizoma Rhei, 2 liang), Huang Qin (Radix Scutellariae, 2 liang), Chuan Mang Xiao (Natrii Sulfas, 2 liang), Zao Tu Mo (Soot from the chimney, 2 liang), Liang Shang Chen (Dust from the beam, 2 liang).
Grind the above ingredients into a fine powder. Mix with refined honey to form pills the size of a bullet. Take one pill at any time, dissolving it in well-water drawn at dawn.