《圣惠》论∶小儿冷热不调者，盖为乳食乖张，寒温失节；或阴阳相胜，气血不调。致令冷归下焦，热冲上
膈。若风冷入于肠胃，则泻痢不定，或腹中气满，或时呕逆不能乳食。故谓之冷热不调也。
张涣论∶小儿所以多疾者，盖为不能自保摄，全在乳母调节。若哺乳乖宜，则冷热不调，热冲上膈，冷归
下焦，致虚实不等。水谷不消，遂伤脾胃，胃气虚则呕吐，脾气虚则泄痢，挟积则变为下痢。盖脾胃居常，最
宜调适。若疾证甚而不已，致令虫动生风，便致危困，岂不慎哉！
《圣惠》治小儿冷热不调，胃气壅滞，少思饮食。木香散方
木香 大腹皮（锉） 人参（去芦头） 赤茯苓 青橘皮（汤浸，去白瓤，焙） 诃
梨勒皮 桂心 前胡（去芦头） 半夏（汤浸七遍，
去滑） 丁香 甘草（炙微赤，锉。各一分）
上件药捣粗为散。每服一钱，以水一盏，入生姜半枣大，煎五分，去滓放温。量儿大小，以意加减服之。
《圣惠》治小儿冷热不调，不思饮食，食即不消。赤芍药丸方
赤芍药 川大黄（锉碎，微炒。各三分） 柴胡（去苗） 赤茯苓（各半两） 桂
心（一分） 鳖甲（涂醋、炙令黄，去裙 用一两）
上件药捣，罗为末，炼蜜和丸如梧桐子大。二岁以上，粥饮化破三丸服，日三服。如四岁以上至七岁服
七丸，以粥饮下。
《圣惠》治小儿冷热不调，腹内疼痛，发歇不定。白术散方
白术 当归（锉碎，微炒） 芎 （各半两） 干姜（炮
制，锉） 青橘皮（汤浸，去白瓤，焙） 甘草（炙赤，锉。各一分）
上件药捣，粗罗为散。每服一钱，以水一小盏，煎至五分，去滓。不计时候，量儿大小，加减服之。
《圣惠》治小儿冷热不调，腹痛下痢。香连散方
木香 当归（锉碎，微炒） 干姜（炮制，锉。各一两） 黄连（去须） 阿胶（捣碎，炒令黄。各半两）
上件捣，细罗为散，每服以粥饮调下半钱。量儿大小，加减频服。
《圣惠》治小儿冷热不调，大便或壅或通，不欲乳食。诃梨勒散方
诃梨勒皮 大黄（锉碎，微炒。各半两） 人参（去芦头） 槟榔 木香 桂心 芎 （各一分）
上件药捣，粗罗为末，每服一钱。以水一小盏，入生姜少许，煎至五分，去滓。不计时候，量儿大小，加
减温服。
《圣惠》治小儿冷热不调，大便青黄，心腹多痛，不欲乳食。当归丸方
当归（锉碎，微炒） 人参（去芦头） 白芍药 芎 （各三分） 甘草（炙微赤，锉） 白术（各半两）
上件药捣，罗为末，以面糊为丸如麻子。每服以粥饮下五丸，日三服。三岁以上，加丸数服之。
《圣惠》治小儿冷热不调，腹痛不可忍，或时寒热，下痢脓血。木香散方
木香（一分） 芎 当归（锉碎，微炒） 桔梗（去芦头） 黄芩（各半两）
上件药捣，罗为末，炼蜜和丸如梧桐子大。不计时候，以温生姜汤研破二丸服之。量大小以意加减。
《圣惠》治小儿四、五岁，腹内冷热不调，不能饮食。调气散方
白术 甘草（炙微赤，锉） 人参（去芦头。各三分） 浓朴（一两，去粗皮，涂生姜汁，炙令香熟）
上件药捣，粗罗为散，每服一钱。以水一盏，入生姜少许，煎至五分，去滓放温。量儿大小分减服之。
《圣惠》治小儿冷热不调，或时下痢，腹痛，不能饮食。犀角散方
犀角（屑） 桂心 甘草（炙微赤，锉） 当归（锉碎，微炒） 黄连（去须） 人参（去芦头）
陈橘皮（汤浸，去白瓤，焙） 干姜（炮裂，锉。各半两）
上件药捣，粗罗为散。每服一钱，以水一小盏，煎至五分，去滓。放温服之，日三服。量儿大小以意加减。
《圣惠》治小儿冷热不调，肠胃滞结，壮热或时，两肋刺痛。赤茯苓丸方
赤茯苓（三分） 当归（锉，微炒） 芎 （各一分） 川大黄（锉碎，微炒） 鳖
甲（涂醋，炙令黄，去裙 。各三分）
上件药捣，罗为末，蜜和丸如绿豆大。每服以粥饮下五丸，日三服。量儿大小以意加减。
太医局和中散 治小儿脾胃不和，呕逆恶心，冷热不调，减食泻泄，腹痛肠鸣，少力嗜卧。
浓朴（去粗皮，生姜汁涂炙，六两） 白术（三两） 干姜（炮） 甘草（炙，锉。各二两）
上为末。每服一钱，水八分一盏，入生姜二片，煎六分，去滓。稍热服，乳食前服。
《谭氏殊圣》治小儿冷热不调，暴泻注下。通心气，利小便。乌犀散
上用拣净车前子杵，罗为末。每服□□甘草汤下，不以时候。
张涣调中散方 治小儿冷热不调致脾胃不和。
青橘皮（汤浸，去白，焙干） 白茯苓 人参（去芦头） 木香（锉。各一两） 丁香 白术（炮） 大
腹皮（锉） 甘草（炙。各半两）
上件捣，罗为细末。每服一钱，水一小盏，入生姜二片，煎至五分，去滓温服。
张涣益胃丹方 调冷热，和脾胃。
当归（洗，焙干） 木香 白术（炮） 沉香（炮。各一两） 白芍药 人参（去芦头） 蓬
莪术 缩砂仁（各半两）
上件捣，罗为细末，白面糊和丸如黍米大。每服十粒至十五粒，点麝香汤下。量儿大小加减。
张涣三棱丹方 调冷热，消宿食。
京三棱（炮，乘热先拍破） 神曲 木香 半夏（生姜八两，同捣成膏，炒黄。各一两） 干姜（炮） 陈
橘皮（浸去白） 丁香 桂心（各半两）
上件为细末，炼蜜和丸如鸡头大。每服一粒，生姜汤化下。
《刘氏家传》三台丸 治五脏寒热不调，或胪胀肠鸣而噫食，甚者呕逆，大便色变。服之令人大小
便调，长肌肉方。
大黄（煨） 前胡（各二两半） 硝石（别研） 葶苈（炒，别研如泥） 杏仁（去皮，别
研烂。各一两） 浓朴（姜制） 附子（炮，去皮） 细辛（去土及叶） 半
夏（汤洗，切，焙） 茯苓（各半两）
上为末，炼蜜和捣，丸如黍米大。每服一岁儿五丸饮下，以大小便调和止药。
《赵氏家传》治小儿冷热不调，泻痢不止，腹中疼痛。三圣方
黄连 干姜（炮） 甘草（炙。等分）
上为末，面糊为丸绿豆大，每服七丸。赤痢甘草汤下，白痢干姜汤下，赤白痢二宜汤下。
《赵氏家传》人参丸 调气，治小儿饮食不消化，冷热不调方。
人参 木香 白术 蓬莪术 当归（细锉，炒。各半两） 白芍药（一分）
上件细末，汤浸，蒸饼为丸如黍米大。每服十丸，空心，麝香汤下，米饮亦得。
*Shenghui Fang* discusses: The imbalance of cold and heat in children is generally caused by improper breastfeeding or diet, and a loss of regulation in cold and warmth; or it may result from the mutual overdominance of Yin and Yang, leading to disharmony of Qi and Blood. This causes coldness to settle in the Lower Jiao (Lower Burner) and heat to rush to the Upper Ge (Diaphragm). If wind-cold enters the intestines and stomach, it leads to unpredictable diarrhea and dysentery, abdominal distension and fullness, or occasional vomiting and regurgitation, making it impossible to take milk and food. Hence, it is called the imbalance of cold and heat.
Zhang Huan discusses: The reason why children are prone to illness is that they cannot protect themselves, relying entirely on their wet nurses for regulation. If breastfeeding is inappropriate, it results in an imbalance of cold and heat, with heat rushing to the Upper Ge and cold settling in the Lower Jiao, causing unequal deficiency and excess. Food and fluids fail to digest, thereby damaging the Spleen and Stomach. Deficiency of Stomach Qi leads to vomiting; deficiency of Spleen Qi leads to diarrhea and dysentery; if complicated by accumulation, it transforms into lower dysentery. Generally, the Spleen and Stomach require proper regulation. If the condition becomes severe and persists, causing worms to move and generating wind, it leads to critical danger. Is this not something to be cautious about!
*Shenghui Fang* treats the imbalance of cold and heat in children, with stagnation of Stomach Qi and reduced appetite, using the *Muxiang San* (Aucklandia Powder) formula:
*Muxiang* (Aucklandiae Radix), *Dafupi* (Arecae Pericarpium) (chopped), *Renshen* (Ginseng Radix et Rhizoma) (removed radix head), *Chifuling* (Polyporus), *Qingjupi* (Aurantii Fructus Viridis) (soaked in decoction, white pith removed, dried), *Helilepi* (Terminaliae Chebulae Pericarpium), *Guixin* (Cinnamomi Ramulus), *Qianhu* (Peucedani Radix) (removed radix head), *Banxia* (Pinelliae Rhizoma) (soaked in decoction seven times, slippery texture removed), *Dingxiang* (Caryophylli Flos), *Gancao* (Glycyrrhizae Radix et Rhizoma) (stir-fried until slightly red, chopped, each 1 fen).
The above medicines are crushed into a coarse powder. Each dose is one qian, boiled with one cup of water and ginger half the size of a jujube, until five fen of liquid remains. Strain and let cool to warm. Adjust dosage according to the child's age and size.
*Shenghui Fang* treats the imbalance of cold and heat in children, lack of appetite, and indigestion after eating, using the *Chishaoyao Wan* (Red Peony Pill) formula:
*Chishaoyao* (Paeoniae Radix Rubra), *Chuandahuang* (Rhei Radix et Rhizoma) (chopped, slightly stir-fried, each 3 fen), *Chaihu* (Bupleuri Radix) (removed seedling), *Chifuling* (Polyporus) (each 0.5 liang), *Guixin* (Cinnamomi Ramulus) (1 fen), *Biejia* (Testudinis Carapax et Plastrum) (coated with vinegar, roasted until yellow, skirt removed, 1 liang).
The above medicines are crushed, sifted into fine powder, and mixed with refined honey to form pills the size of paulownia seeds. For children over two years old, dissolve three pills in rice gruel and drink, three times daily. For children aged four to seven, take seven pills with rice gruel.
*Shenghui Fang* treats the imbalance of cold and heat in children, abdominal pain with intermittent attacks, using the *Baizhu San* (Atractylodes Macrocephala Powder) formula:
*Baizhu* (Atractylodis Macrocephalae Rhizoma), *Danggui* (Angelicae Sinensis Radix) (chopped, slightly stir-fried), *Xiong* (Ligustici Chuanxiong Rhizoma) (each 0.5 liang), *Ganjiang* (Zingiberis Rhizoma) (processed, chopped), *Qingjupi* (Aurantii Fructus Viridis) (soaked in decoction, white pith removed, dried), *Gancao* (Glycyrrhizae Radix et Rhizoma) (roasted until red, chopped, each 1 fen).
The above medicines are crushed and coarsely sifted into a powder. Each dose is one qian, boiled with a small cup of water until five fen of liquid remains. Strain. Take at any time, adjusting dosage according to the child's age and size.
*Shenghui Fang* treats the imbalance of cold and heat in children, abdominal pain with dysentery, using the *Xianglian San* (Aucklandia and Coptis Powder) formula:
*Muxiang* (Aucklandiae Radix), *Danggui* (Angelicae Sinensis Radix) (chopped, slightly stir-fried), *Ganjiang* (Zingiberis Rhizoma) (processed, chopped, each 1 liang), *Huanglian* (Coptidis Rhizoma) (removed stamens), *E'jiao* (Colla Corii Asini) (crushed, roasted until yellow, each 0.5 liang).
The above medicines are crushed and finely sifted into a powder. Each dose is half a qian, mixed with rice gruel. Adjust frequency and dosage according to the child's age and size.
*Shenghui Fang* treats the imbalance of cold and heat in children, bowel movements alternating between obstruction and passage, and reluctance to nurse, using the *Helile San* (Terminalia Powder) formula:
*Helilepi* (Terminaliae Chebulae Pericarpium), *Dahuang* (Rhei Radix et Rhizoma) (chopped, slightly stir-fried, each 0.5 liang), *Renshen* (Ginseng Radix et Rhizoma) (removed radix head), *Bolang* (Arecae Semen), *Muxiang* (Aucklandiae Radix), *Guixin* (Cinnamomi Ramulus), *Xiong* (Ligustici Chuanxiong Rhizoma) (each 1 fen).
The above medicines are crushed and coarsely sifted into powder. Each dose is one qian. Boil with a small cup of water and a little ginger until five fen of liquid remains. Strain. Take warm at any time, adjusting dosage according to the child's age and size.
*Shenghui Fang* treats the imbalance of cold and heat in children, greenish-yellow stools, frequent heart and abdominal pain, and reluctance to nurse, using the *Danggui Wan* (Angelica Pill) formula:
*Danggui* (Angelicae Sinensis Radix) (chopped, slightly stir-fried), *Renshen* (Ginseng Radix et Rhizoma) (removed radix head), *Baishaoyao* (Paeoniae Radix Alba), *Xiong* (Ligustici Chuanxiong Rhizoma) (each 3 fen), *Gancao* (Glycyrrhizae Radix et Rhizoma) (roasted until slightly red, chopped), *Baizhu* (Atractylodis Macrocephalae Rhizoma) (each 0.5 liang).
The above medicines are crushed and sifted into powder, mixed with flour paste to form pills the size of hemp seeds. Each dose is five pills taken with rice gruel, three times daily. For children over three years old, increase the number of pills.
*Shenghui Fang* treats the imbalance of cold and heat in children, unbearable abdominal pain, occasional chills and fever, and dysentery with pus and blood, using the *Muxiang San* (Aucklandia Powder) formula:
*Muxiang* (Aucklandiae Radix) (1 fen), *Xiong* (Ligustici Chuanxiong Rhizoma), *Danggui* (Angelicae Sinensis Radix) (chopped, slightly stir-fried), *Jiegeng* (Platycodonis Radix) (removed radix head), *Huangqin* (Scutellariae Radix) (each 0.5 liang).
The above medicines are crushed and sifted into fine powder, mixed with refined honey to form pills the size of paulownia seeds. Take at any time, crushing two pills in warm ginger decoction. Adjust dosage according to the child's age and size.
*Shenghui Fang* treats four- or five-year-old children with internal imbalance of cold and heat and inability to eat, using the *Tiaoqi San* (Regulating Qi Powder) formula:
*Baizhu* (Atractylodis Macrocephalae Rhizoma), *Gancao* (Glycyrrhizae Radix et Rhizoma) (roasted until slightly red, chopped), *Renshen* (Ginseng Radix et Rhizoma) (removed radix head, each 3 fen), *Noupo* (Magnoliae Officinalis Cortex) (1 liang, outer bark removed, coated with ginger juice, roasted until fragrant).
The above medicines are crushed and coarsely sifted into powder. Each dose is one qian. Boil with one cup of water and a little ginger until five fen of liquid remains. Strain and let cool to warm. Divide and reduce dosage according to the child's age and size.
*Shenghui Fang* treats the imbalance of cold and heat in children, occasional dysentery, abdominal pain, and inability to eat, using the *Xijiao San* (Rhinoceros Horn Powder) formula:
*Xijiao* (Rhinocerotis Cornu) (shredded), *Guixin* (Cinnamomi Ramulus), *Gancao* (Glycyrrhizae Radix et Rhizoma) (roasted until slightly red, chopped), *Danggui* (Angelicae Sinensis Radix) (chopped, slightly stir-fried), *Huanglian* (Coptidis Rhizoma) (removed stamens), *Renshen* (Ginseng Radix et Rhizoma) (removed radix head), *Chenjupi* (Citri Reticulatae Pericarpium) (soaked in decoction, white pith removed, dried), *Ganjiang* (Zingiberis Rhizoma) (cracked by processing, chopped, each 0.5 liang).
The above medicines are crushed and coarsely sifted into powder. Each dose is one qian, boiled with a small cup of water until five fen of liquid remains. Strain. Take warm, three times daily. Adjust dosage according to the child's age and size.
*Shenghui Fang* treats the imbalance of cold and heat in children, stagnation and knotting in the intestines and stomach, high fever occasionally, and stabbing pain in both hypochondria, using the *Chifuling Wan* (Polyporus Pill) formula:
*Chifuling* (Polyporus) (3 fen), *Danggui* (Angelicae Sinensis Radix) (chopped, slightly stir-fried), *Xiong* (Ligustici Chuanxiong Rhizoma) (each 1 fen), *Chuandahuang* (Rhei Radix et Rhizoma) (chopped, slightly stir-fried), *Biejia* (Testudinis Carapax et Plastrum) (coated with vinegar, roasted until yellow, skirt removed, each 3 fen).
The above medicines are crushed and sifted into fine powder, mixed with honey to form pills the size of mung beans. Each dose is five pills taken with rice gruel, three times daily. Adjust dosage according to the child's age and size.
Taiyi Bureau's *Hezhong San* (Harmonizing Middle Powder): Treats disharmony of Spleen and Stomach in children, vomiting and nausea, imbalance of cold and heat, reduced appetite and diarrhea, abdominal pain and borborygmus, fatigue, and lethargy.
*Noupo* (Magnoliae Officinalis Cortex) (outer bark removed, coated with ginger juice and roasted, 6 liang), *Baizhu* (Atractylodis Macrocephalae Rhizoma) (3 liang), *Ganjiang* (Zingiberis Rhizoma) (processed), *Gancao* (Glycyrrhizae Radix et Rhizoma) (roasted, chopped, each 2 liang).
The above are made into powder. Each dose is one qian, boiled with eight-tenths of a cup of water and two slices of ginger until six-tenths remain. Strain. Take slightly warm, before nursing or eating.
*Tan Shi Shusheng* treats sudden watery diarrhea due to imbalance of cold and heat in children, promoting Heart Qi and benefiting urination, using *Wuxi San* (Black Rhinoceros Powder):
Use clean *Cheqianzi* (Plantaginis Semen), crush and sift into fine powder. Each dose [text missing] is taken with Licorice decoction, at any time.
Zhang Huan's *Tiaozhong San* (Regulating Middle Powder): Treats disharmony of Spleen and Stomach caused by imbalance of cold and heat in children.
*Qingjupi* (Aurantii Fructus Viridis) (soaked in decoction, white part removed, dried), *Baifuling* (Poria), *Renshen* (Ginseng Radix et Rhizoma) (removed radix head), *Muxiang* (Aucklandiae Radix) (chopped, each 1 liang), *Dingxiang* (Caryophylli Flos), *Baizhu* (Atractylodis Macrocephalae Rhizoma) (processed), *Dafupi* (Arecae Pericarpium) (chopped), *Gancao* (Glycyrrhizae Radix et Rhizoma) (roasted, each 0.5 liang).
The above are crushed and sifted into fine powder. Each dose is one qian, boiled with a small cup of water and two slices of ginger until five fen of liquid remains. Strain and take warm.
Zhang Huan's *Yiwei Dan* (Benefit Stomach Elixir): Regulates cold and heat, harmonizes Spleen and Stomach.
*Danggui* (Angelicae Sinensis Radix) (washed, dried), *Muxiang* (Aucklandiae Radix), *Baizhu* (Atractylodis Macrocephalae Rhizoma) (processed), *Chenxiang* (Aquilariae Lignum Resinatum) (processed, each 1 liang), *Baishaoyao* (Paeoniae Radix Alba), *Renshen* (Ginseng Radix et Rhizoma) (removed radix head), *Peng'e Zhu* (Curcumae Phaeocaulis Rhizoma), *Suosharen* (Amomi Fructus Rotundus) (each 0.5 liang).
The above are crushed and sifted into fine powder, mixed with white flour paste to form pills the size of millet grains. Each dose is ten to fifteen pills, taken with musk-infused water. Adjust dosage according to the child's age and size.
Zhang Huan's *Sanleng Dan* (Sedge Elixir): Regulates cold and heat, eliminates retained food.
*Jingsanleng* (Smilacis Glabrae Rhizoma) (processed, cracked while hot), *Shenqu* (Massa Medicata Fermentata), *Muxiang* (Aucklandiae Radix), *Banxia* (Pinelliae Rhizoma) (with 8 liang of fresh ginger, pounded into paste, stir-fried until yellow, each 1 liang), *Ganjiang* (Zingiberis Rhizoma) (processed), *Chenjupi* (Citri Reticulatae Pericarpium) (soaked, white part removed), *Dingxiang* (Caryophylli Flos), *Guixin* (Cinnamomi Ramulus) (each 0.5 liang).
The above are made into fine powder, mixed with refined honey to form pills the size of a cockle. Each dose is one pill, dissolved and taken with ginger decoction.
*Liu Shi Jia Chuan* *Santai Wan* (Three Terraces Pill): Treats imbalance of cold and heat in the Five Zang organs, abdominal distension with borborygmus and belching of undigested food, severe vomiting and regurgitation, and changes in stool color. Taking it harmonizes urination and defecation and promotes muscle growth.
*Dahuang* (Rhei Radix et Rhizoma) (baked), *Qianhu* (Peucedani Radix) (each 2.5 liang), *Xiaoshi* (Natrii Sulfas) (separately ground), *Tingli* (Descurainiae Semen seu Lepidii Semen) (fried, separately ground into paste), *Xingren* (Armeniacae Semen Amarum) (skin removed, separately ground to a paste, each 1 liang), *Noupo* (Magnoliae Officinalis Cortex) (ginger-processed), *Fuzi* (Aconiti Lateralis Radix Praeparata) (processed, skin removed), *Xixin* (Asari Radix et Rhizoma) (dirt and leaves removed), *Banxia* (Pinelliae Rhizoma) (washed in decoction, sliced, dried), *Fuling* (Poria) (each 0.5 liang).
The above are made into powder, mixed with refined honey and pounded, forming pills the size of millet grains. One-year-old infants take five pills with water. Stop medication when urination and defecation are harmonized.
*Zhao Shi Jia Chuan* *Sansheng Fang* (Three Sage Formula): Treats imbalance of cold and heat in children, persistent diarrhea and dysentery, and abdominal pain.
*Huanglian* (Coptidis Rhizoma), *Ganjiang* (Zingiberis Rhizoma) (processed), *Gancao* (Glycyrrhizae Radix et Rhizoma) (roasted, equal parts).
The above are made into powder, mixed with flour paste to form pills the size of mung beans. Each dose is seven pills. For bloody dysentery, take with licorice decoction; for white dysentery, take with ginger decoction; for mixed bloody and white dysentery, take with a mixture of both decoctions.
*Zhao Shi Jia Chuan* *Renshen Wan* (Ginseng Pill): Regulates Qi, treats indigestion and imbalance of cold and heat in children.
*Renshen* (Ginseng Radix et Rhizoma), *Muxiang* (Aucklandiae Radix), *Baizhu* (Atractylodis Macrocephalae Rhizoma), *Peng'e Zhu* (Curcumae Phaeocaulis Rhizoma), *Danggui* (Angelicae Sinensis Radix) (finely chopped, fried, each 0.5 liang), *Baishaoyao* (Paeoniae Radix Alba) (1 fen).
The above are made into fine powder, soaked in decoction, and formed into pills the size of millet grains using steamed bread dough. Each dose is ten pills, taken on an empty stomach with musk-infused water, or rice gruel is also acceptable.