(疟母详细当与积聚参看)
总括 面黄发竖疟之因,外感风寒暑湿成;内郁七情饥饿后,故令寒热往来生。
脉法 疟脉因弦,微则为虚,代散则死。
《内经》曰∶夏暑汗不出者,秋成风疟。又曰∶夏伤于暑,秋必 疟。丹溪曰∶ 疟皆生于风。此前人论疟之大概
也。殊不知风寒暑湿邪自外来,饮食居处邪由内作,岂特夏伤于暑,秋必发疟哉!盖伤之浅者近而暴,伤之深者远而为
, 者久疟也。要知疟之寒热,乃阴阳之二气互相胜负而作也。邪并于巨阳则阴实阳虚,故寒作;邪并于巨阴则阳实
而阴虚故热作,此阴阳相移也。病气舍于皮肤与卫气并居,卫气者日行阳、夜行阴,此气得阳而外出,得阴而内薄,是
以日作,此受之浅也。其气之舍深,薄于五脏,阳气独发,阴邪内着,阴与阳终争不得出,故间日作,此受之深也。邪
气与卫气客于六腑,而有时相失,不能相争,故休数日乃作,此受之最深也。然疟之状不一,足太阳疟(膀胱经)令人
腰痛头重,寒从背起,先寒后热, 然,热止汗出乃已;足少阳疟(胆经)令人身体解 ,寒不甚,热不甚,恶见人,
见人则惕惕然,热多汗甚;足阳明疟(胃经)令人先淅淅寒,寒久乃热,热去汗出,喜见日月,火气乃快;然足太阴疟
(脾经)令人不乐,好太息,不嗜食,多寒热,汗出,病至则喜呕,呕已乃衰;足少阴疟(肾经)令人呕吐甚,热多寒
少,欲闭户而处,其病难矣;足厥阴疟(肝经)令人腰痛,小腹满,小便不利,如癃非癃也,数便意,恐惧气不足,腹
中悒悒,此六经之疟也。肺疟者令人寒,寒甚热,热间善惊,如有所见;心疟者令人烦甚,欲得清水,反寒多不甚
热;肝疟者令人色苍苍然太息,其状若死者;脾疟者令人寒,
腹中痛,热则肠鸣,鸣已汗出;肾疟者令人洒洒然腰脊痛,宛转大便难,目眩眩然,此五脏之疟也。
东垣云∶寒疟属太阴,热疟属阳明,风疟属少阴,温疟属厥阴。又作于子午卯酉日者属少阴,作于寅申巳亥日者属
厥阴,作于辰戌丑未日者属太阴,盖三日一作故耳。而丹溪又有食疟、痰疟、风疟、暑疟、老疟、疟母之名,皆不越乎
五脏六腑经之所主也,但所感不同耳!然因其所挟而立名也。今并及之,以备参考。若夫小儿抱持解脱,不避风寒,又
冒暑湿,致令邪气客于皮肤,痰饮乳食溃于脏腑。初起虽先于消导,然抉胃气为本,后随其得病所由而调理之。如邪疟
及暂发者,可散可截。虚疟及久者,宜补气血,若过服截药,致伤脾胃则必延绵不休。凡热多寒少,无汗者,桂枝麻黄
各半汤。汗多者,柴胡桂枝汤。汗多而渴者,白虎加桂枝汤。小便赤,热多寒少者,小柴胡汤。寒多热少者,用清脾饮、
养胃汤。久不止者,鬼哭散止之。热多汗出,腹痛而渴者,大柴胡汤下之。久疟不愈,肠中结块者,鳖甲饮调之。凡脾
虚而患疟者,不论三阴六经,悉以六君子汤为主,热多加柴胡、山栀、黄芩,甚者加知母、地骨皮、鳖甲。寒多加干姜、
肉桂。有汗加黄 、浮麦。无汗加苍术、葛根。元气下陷及肝木乘脾并加升麻、柴胡为善。若用青皮、常山、草果之类,
正气益虚,邪气益深而变症百端矣。
有小儿疟疾,变作虚浮,外肾肿大,或食伤脾胃,以致浮肿。夫浮者脾之外应也,宜大腹皮汤、草果饮治之。然后
以实脾补剂进之可也。若乳母七情六欲不调及饮食不节,或寒热似疟,肝火炽盛,致儿为患者,又当治其乳母斯无误矣。
有阴虚症,每日午后恶寒发热,似乎疟者,至晚亦得汗而解,若作疟治,而用常山、草果等药,误矣!且阴虚脉虚
濡而数,疟脉弦数为辨耳。有癖痞而为寒热似疟者,亦不可作疟治也。
(批∶久疟则元气虚损,若误服清脾饮,多致不起,慎之。截疟饮亦不宜服。疟后食少无力,面黄身弱,以四君子
汤加二陈汤、姜汁炒黄连、枳实。若草果常山性猛善驱逐,病患稍虚者勿用。)
疟脉弦数肾胃虚,外感内伤共有之,归芎人参鳖甲饮,半朴槟青甘草施。二术乌梅姜黑豆,桃枝煎酒露饮之。寒多
加桂因寒盛,热多柴苓酒炒宜。渴加知母天花粉,元气不足升麻提。夜发升麻加桔梗,久疟常山草果随。截法常山苍浓
朴,陈皮黄连槟榔果,七味乌梅酒水煎,何首茯苓三四两,二三陈朴不须言,十分甘草煎宿露,药饮空心疟遇仙。
〔附方〕
桂枝麻黄各半汤 桂枝 白芍 麻黄 甘草 杏仁 生姜 大枣
柴胡桂枝汤 柴胡 桂枝 黄芩 半夏 人参 甘草
白虎加桂枝汤 石膏 知母 桂枝 甘草
小柴胡汤 见诸吐症内(去薄荷)。
清脾饮(初起者宜服) 苍术 半夏 草果 青皮 黄芩 柴胡 浓朴 陈皮 茯苓 枳壳 紫苏 甘草
养胃汤(病虚者宜服) 藿香 苍术 浓朴 半夏 陈皮 草果 茯苓 人参 甘草
鬼哭散 大腹皮 常山 茯苓 鳖甲
大柴胡汤 柴胡 黄芩 半夏 芍药 枳实 甘草 大黄(酒制)
鳖甲饮(李自才用何首乌红白各半,酒煎服)白术 陈皮 草果 川芎 芍药
槟榔 黄芩 浓朴 鳖甲 甘草
六君子汤 人参 白术 茯苓 甘草 陈皮 半夏
大腹皮汤 枳壳 苍术 槟榔 甘草 三棱 蓬术 大腹皮
草果饮 浓朴 青皮 草果 藿香 半夏 丁香 甘草 干姜 神曲
(Detailed information on Malaria Mother (Nue Mu) should be referred to alongside Accumulation and Mass (Ji Ju).)
General Summary: Yellowish complexion and erect hair indicate the causes of malaria; it arises from external contraction of Wind, Cold, Summerheat, and Dampness. Internally, it results from emotional stagnation or following hunger, thus causing alternating chills and fever.
Pulse Diagnosis: The pulse in malaria is typically Wiry (Xian). If the pulse is Fine (Wei), it indicates Deficiency. If the pulse is Intermittent (Dai) and Scattered (San), it indicates a fatal prognosis.
The *Neijing* states: Those who do not sweat during summer heat will develop Wind Malaria (Feng Nue) in autumn. It also states: Injury by Summerheat in summer leads to malaria in autumn. Zhu Danxi stated: All malaria originates from Wind pathogen. This represents the general understanding of previous scholars regarding malaria. However, they failed to realize that Wind, Cold, Summerheat, and Dampness pathogens enter from outside, while pathogens due to diet and lifestyle arise from within. It is not merely that injury by summer heat in summer inevitably leads to malaria in autumn! Generally, shallow injuries manifest quickly and acutely, while deep injuries manifest slowly and chronically; chronic cases are known as Long-term Malaria (Jiu Nue). One must understand that the alternating chills and fever in malaria result from the mutual struggle between Yin and Yang Qi. When pathogens congregate in the Greater Yang (Ju Yang) meridian, Yin becomes Excess and Yang becomes Deficient, hence chills occur first. When pathogens congregate in the Greater Yin (Ju Yin) meridian, Yang becomes Excess and Yin becomes Deficient, hence fever occurs. This is the shifting of Yin and Yang. Pathogenic qi resides in the skin and coexists with Defensive Qi (Wei Qi). Defensive Qi travels through Yang during the day and Yin at night. When this pathogen obtains Yang Qi, it moves outward causing an attack; when it obtains Yin Qi, it presses inward causing remission. Thus, daily attacks indicate shallow infection. When the pathogen resides deeply, affecting the Five Zang organs, Yang Qi flares up alone while Yin pathogen lingers inside. Yin and Yang struggle endlessly without exiting, resulting in every-other-day attacks, indicating deeper infection. When pathogenic qi and Defensive Qi lodge in the Six Fu organs but sometimes fail to interact, unable to struggle, remission lasts several days before an attack, indicating the deepest infection.
However, malaria symptoms vary:
Foot-Taiyang Malaria (Bladder Meridian) causes lower back pain and heavy head, cold sensation rising from the back, preceded by chills then fever, body stiffness, ending only after sweating ceases.
Foot-Shaoyang Malaria (Gallbladder Meridian) causes bodily laxity, mild chills and mild fever, aversion to people, trembling upon seeing others, abundant fever and sweating.
Foot-Yangming Malaria (Stomach Meridian) causes initial shivering cold, followed by fever after prolonged cold, ending with sweating and relief upon exposure to sunlight or moonlight.
Foot-Taiyin Malaria (Spleen Meridian) causes melancholy, frequent sighing, loss of appetite, alternating chills and fever, sweating, nausea upon onset, with improvement after vomiting.
Foot-Shaoyin Malaria (Kidney Meridian) causes severe vomiting, more fever than chills, desire to stay indoors with doors closed, and is difficult to treat.
Foot-Jueyin Malaria (Liver Meridian) causes lower back pain, abdominal fullness, difficulty urinating (resembling strangury but not quite), frequent urge to urinate, fearfulness, Qi deficiency, and abdominal depression. These are the six-meridian malarias.
Lung Malaria causes chills, severe cold then severe heat, fright during heat intervals, and visual hallucinations.
Heart Malaria causes extreme irritability, desire for cold water, yet more chills than heat.
Liver Malaria causes pale/greenish complexion, frequent sighing, and a state resembling death.
Spleen Malaria causes chills, abdominal pain, borborygmus during fever, and sweating after borborygmus.
Kidney Malaria causes aversive cold, lower back and spine pain, restlessness, difficulty defecating, dizziness, and blurred vision. These are the five-zang malarias.
Li Dongyuan stated: Cold Malaria belongs to Taiyin, Heat Malaria to Yangming, Wind Malaria to Shaoyin, and Warm Malaria to Jueyin. Attacks occurring on Zi, Wu, Mao, You days belong to Shaoyin; those on Yin, Shen, Si, Hai days belong to Jueyin; those on Chen, Xu, Chou, Wei days belong to Taiyin, due to the tri-day cycle.
Danxi also named Food Malaria, Phlegm Malaria, Wind Malaria, Summerheat Malaria, Old Malaria, and Malaria Mother. These do not exceed the domains of the Five Zang and Six Fu meridians, differing only in the specific pathogen contracted. They are named according to the accompanying pathogen. These are listed here for reference.
Regarding children, if they are held improperly, exposed to Wind and Cold, or suffer Summerheat and Dampness, pathogens lodge in the skin, and Phlegm-Fluids, Milk, and Food stagnate in the Zang-Fu. Initially, resolution and guidance methods may be used, but protecting Stomach Qi is fundamental. Subsequent treatment should follow the cause. For acute or transient malaria, dispersal or interception can be used. For deficient or chronic malaria, tonifying Qi and Blood is appropriate. Overuse of intercepting drugs damages Spleen and Stomach, leading to lingering illness.
For Heat-dominant, Cold-minimal, anhidrosis: Guizhi Mahuang Ban Ge Tang (Cinnamon Twig and Ephedra Half-Dose Decoction).
For hyperhidrosis: Chaihu Guizhi Tang (Bupleurum and Cinnamon Twig Decoction).
For hyperhidrosis with thirst: Baihu Jia Guizhi Tang (White Tiger plus Cinnamon Twig Decoction).
For red urine, Heat-dominant, Cold-minimal: Xiaochaihu Tang (Minor Bupleurum Decoction).
For Cold-dominant, Heat-minimal: Qingpi Yin (Clear the Spleen Drink) or Yangwei Tang (Nourish the Stomach Decoction).
For chronic non-resolving cases: Gui Ku San (Ghost Cry Powder).
For Heat-dominant, sweating, abdominal pain, thirst: Daxiehu Tang (Major Bupleurum Decoction) to purge.
For chronic malaria with intestinal masses: Biejia Yin (Turtle Shell Drink).
For malaria with Spleen Deficiency, regardless of meridian involvement, Liu Junzi Tang (Six Gentlemen Decoction) is primary. Add Chaihu, Zhizi, Huangqin for heat; add Zhimu, Digupi, Biejia for severe heat. Add Ganjiang, Rougui for cold. Add Huangqi, Fumai for sweating. Add Cangzhu, Gegen for no sweating. For sinking Yuan Qi or Liver Wood overacting on Spleen, add Shengma, Chaihu. Avoid Qipi, Changshan, Caoguo, as they further deplete Zheng Qi and deepen pathogens, causing myriad complications.
Some pediatric malaria transforms into deficiency edema or scrotal swelling, or dietary injury to Spleen/Stomach causes edema. Edema reflects Spleen pathology; treat with Dafupi Tang (Areca Peel Decoction) or Caoguo Yin (Caoguo Drink). Follow with Spleen-fortifying tonics.
If the nursing mother has emotional/dietary imbalance, presenting with malaria-like chills/fever and blazing Liver Fire affecting the infant, treat the mother instead.
Yin Deficiency syndrome presents with afternoon chills and fever resembling malaria, resolving with evening sweat. Treating as malaria with Changshan/Caoguo is erroneous. Differentiate by pulse: Yin Deficiency shows Empty, Soft, Rapid pulse; Malaria shows Wiry, Rapid pulse.
Masses (Pi Pi) causing malaria-like chills/fever should not be treated as malaria.
(Note: Chronic malaria depletes Yuan Qi. Misusing Qingpi Yin often proves fatal; use caution. Jiemai Yin is also unsuitable. Post-malaria poor appetite, weakness, yellow face, and frailty: Use Sijunzi Tang combined with Erchen Tang, Ginger-processed Huanglian, and Zhishi. Caoguo and Changshan are harsh and draining; avoid in slightly deficient patients.)
Malaria with Wiry-Rapid pulse indicates Kidney/Stomach Deficiency, common in both external and internal injuries. Use Guixiong Renshen Biejia Yin (Angelica, Ligusticum, Ginseng, Turtle Shell Decoction): Banxia, Houpo, Binglang, Qingpi, Gancao, Baizhu, Cangzhu, Wumei, Shengjiang, Heidou. Decoct with Peach Branch wine dew. Add Guizhi for severe cold; add Chaihu, Lingzhi (fried in wine) for severe heat. Add Zhimu, Tianhuafen for thirst; add Shengma for insufficient Yuan Qi. For night attacks, add Shengma, Jiegeng. For chronic malaria, adjust Changshan, Caoguo.
Interception method: Changshan, Cangzhu, Houpo, Chenpi, Huanglian, Binglang, Caoguo. Seven ingredients plus Wumei decocted in water/wine. Plus Heshouwu, Fuling (3-4 liang). Erchen Tang and Houpo omitted. Gancao (10 parts) decocted in overnight dew. Take on empty stomach.
[Attached Formulas]
Guizhi Mahuang Ban Ge Tang: Guizhi, Baishao, Mahuang, Gancao, Xingren, Shengjiang, Dazao.
Chaihu Guizhi Tang: Chaihu, Guizhi, Huangqin, Banxia, Renshen, Gancao.
Baihu Jia Guizhi Tang: Shigao, Zhimu, Guizhi, Gancao.
Xiaochaihu Tang: See Vomiting Syndromes (remove Bohe).
Qingpi Yin (Suitable for early stage): Cangzhu, Banxia, Caoguo, Qingpi, Huangqin, Chaihu, Houpo, Chenpi, Fuling, Zhiqiao, Zisu, Gancao.
Yangwei Tang (Suitable for deficiency): Huoxiang, Cangzhu, Houpo, Banxia, Chenpi, Caoguo, Fuling, Renshen, Gancao.
Gui Ku San: Dafupi, Changshan, Fuling, Biejia.
Daxiehu Tang: Chaihu, Huangqin, Banxia, Shaoyao, Zhishi, Gancao, Dahuang (wine-processed).
Biejia Yin (Li Zicai uses equal parts Red/White Heshouwu, decocted in wine): Baizhu, Chenpi, Caoguo, Chuanxiong, Shaoyao, Binglang, Huangqin, Houpo, Biejia, Gancao.
Liu Junzi Tang: Renshen, Baizhu, Fuling, Gancao, Chenpi, Banxia.
Dafupi Tang: Zhiqiao, Cangzhu, Binglang, Gancao, Sanleng, Pengze, Dafupi.
Caoguo Yin: Houpo, Qingpi, Caoguo, Huoxiang, Banxia, Dingxiang, Gancao, Ganjiang, Shenqu.