夫阴气盛而阳暴绝。则为阴毒。若阳气盛而阴暴绝。则为阳毒。大凡阴阳离绝。非大汗
不能复其正气也。六脉俱洪大。或沉。取之大而不甚疾者。非阴证也。阳毒。其脉当弦而洪
数。阴毒。其脉沉细而疾。阳病。则身热而无汗。阴病。则身冷而有汗。岐伯云。阳胜则身
热。腠理闭。喘粗为之俯仰。汗不出而热。阴胜。则身寒汗出。数栗而寒。寒则厥。此证不
可以常法治之。金匮论阳毒之为病。面赤。斑斑如锦纹。咽喉痛。唾脓血。五日可治。七日
不可治。阴毒之为病。面目青。身疼。状如被打。咽喉痛。死生与阳毒同。三因云。病者。
头重颈直。皮肉强痹。或蕴而结核。起于喉颈之侧。布热毒于皮肤分肉之中。上散入发际。
下贯颞 。隐隐而热。不相断离。病名黄肉随。以四季。各十八戊己日。其病从太阴阳明相
格。寒湿不调。关节格滞。若腑虚。则皮肉强痹。若脏实。则布毒热于皮肤。又云。病者。
里热外寒。意欲守火。而反引饮。腰痛欲折。或胸胁切痛。类如刀刺。不得转动。热彭彭。
服冷多。则洞泻。病名黑骨温。以冬三月。源从足太阳、少阴相搏。蕴积壅塞。若腑虚。为
阴毒所伤。则里热外寒。若脏实。为阳毒所损。则彭彭发热。又云。病者发热。腰痛强急。
脚缩不伸。 中欲折。目中生花。或涩涩憎寒复热。颈中双筋。牵不得屈伸。项直背强。眼
赤黄。欲转动。称身回侧。病名青筋牵者。由春三月。其源从厥阴涉足少阳。少阳之气始发。
少阴之气始衰。阴阳怫郁于腠理。腑脏受厉而生。若腑虚。则为阴邪所伤。故发热。若脏实。
则
病名赤脉KT 者。以夏三月。其病从少阴、太阳之气相搏而停。则荣卫不通。皮肉痛起。
太阳发动。少阴淫邪之气。因而作厉。则脏腑随时受疫病也。若腑虚。为阴邪所伤。则寒战。
若
方
治青筋牵（三因方）肝腑脏温病。阴阳毒。胆腑虚。为阴邪所伤。腰胁强急。
脚缩
不伸。
柴胡（去苗五两） 茯苓 栀子仁 半夏（汤洗） 大青（各三两） 桂心 竹茹 香
豉甘
草（
又方（三因方）肝腑脏温病。阴阳毒。肝脏实。为阳毒所伤。涩涩恶寒。翕翕
发热。颈外双
玄参（一两） 细辛（二两） 栀子仁 黄芩 升麻 芒硝（各三两） 石膏（ 八两）
上锉
散。每服五钱。水二盏。入车前草三叶。淡竹叶七片。煎七分。去滓。空心服。
治赤脉KT （三因方）心腑脏温病。阴阳毒。若腑虚。为阴邪所胜。脉促。
身颤掉不能禁。色
茯苓 人参 桔梗（各三分） 甘草（一两半） 白芷 青皮（各一两） 干姜（炮半
两） 上
锉散。每服五钱。水二盏。煎七分。去滓。食前服。
又方（三因方）心腑脏温病。阴阳毒。心脏实。则为阳毒所伤。内热。口干舌
破。咽塞声嘶
天门冬（去心） 麦门冬（去心） 车前子（炒） 栀子仁 黄芩 升麻 甘草（炙） 寒
水石
（
治黄肉随（三因方）脾腑脏温病。阴阳毒。胃腑虚。则为阴邪所伤。头重颈
直。皮肉强痹。
浓朴（姜制炒一两半） 白术 陈皮（各一半） 干姜（炮） 紫苏 甘草（炙） 半夏（汤洗
各三分） 上锉散。每服五钱。水二盏。煎七分。去滓。食前服。
又方（三因方）脾腑脏温病。阴阳毒。脾脏实为阳毒所伤。蕴热结核。起于喉
颈之侧。布毒
葛根 苍术（泔浸） 升麻 白芷 桔梗 青皮（各一两） 大黄（半两） 上锉散。
每服五
钱。水二盏。煎七分。去滓。食前服。
治白气狸（三因方）肺腑脏温病。阴阳毒。太阳腑虚。为阴邪所伤。寒热互
作。上气咳逆。大肠飧泄。色皓皓白者。
白术 人参（各一两） 干姜（炮） 麦 （炒各三分） 白茯苓 五味子 肉豆蔻 草
果
乌梅 甘草（炙各半两） 上锉散。每服五钱。水二盏半。煎七分。去滓。食前服。
又方（三因方）肺腑脏温病。阴阳毒。肺脏实。为阳毒所伤。体热。肌肤发
斑。气喘引饮。
紫菀茸（一两） 栀子仁 升麻 前胡（各三分） 石膏（ 半两） 葶苈（炒一分） 杏
仁
（去皮尖） 甘草（炙各半两） 上锉散。每服五钱。水二盏。煎七分。去滓。食前服。
治黑骨温（三因方）肾腑脏温病。阴阳毒。膀胱腑虚。为阴邪所伤。里热外
寒。烦渴引饮。
附子（炮去皮脐） 茯苓（各一两） 山茱萸 细辛 山药 泽泻（各半两） 麻黄（三
分）
杏仁（去皮尖一分） 上锉散。每服五钱。水二盏。煎七分。去滓。食前服。
又方（三因方）肾腑脏温病。阴阳毒。肾脏实。为阳毒所伤。腰胁切痛。不得
转动。大小便秘涩。小腹胀。食冷则洞泄。色熏黑者。
吴茱萸 黑牵牛（炒） 桃仁（去皮尖） 萆 杜仲（去皮锉姜汁制炒丝断） 大黄
（蒸各
等分） 上锉散。每服五钱。水二盏。煎七分。去滓。食前服。
治肝腑脏温病。阴阳毒。颈背双筋牵。先寒后热。腰强急缩。目中生花。（出千
金
方）
桂心（一两） 白术 芒硝 大青 栀子（各三两） 柴胡（五两） 石膏 生姜（各
八两）
生地黄 香豉（各一升） 上 咀。以水九升。煮取三升。分三服。
治心腑脏温病。阴阳毒。战掉不定。惊动。（出千金方）
大青 黄芩 栀子 知母 芒硝（各三两） 麻黄（四两） 玄参（六两） 石膏 生
葛根
（各八两） 生地黄（切一升） 上 咀。以水九升。煮取三升。去滓。下芒硝。分三服。
治脾腑脏温病。阴阳毒。头重颈直。皮肉痹。结核隐起。（出千金方）
大青 羚羊角 升麻 射干 芒硝（各三两） 栀子（四两） 寒水石（六两） 玄参
（八两）
上咀。以水七升。煮取三升。分三服。
治肺腑脏温病。阴阳毒。咳嗽连续声不绝。呕逆。（出千金方）
麻黄 栀子 紫菀 大青 玄参 葛根（各三两） 桂心 甘草 杏仁 前胡（各四两）
石膏（八两） 上 咀。以水九升。煮取三升。分三服。
治肾腑脏温病。身面如刺。腰中欲折。热毒内伤。（出千金方）
茵陈蒿 栀子 芒硝（各三两） 苦参 生葛（各四两） 生地黄 石膏（各八两） 葱
白
豉（一升） 上 咀。以水九升。煮取二升半。下硝。分三服。
大交泰丹 治阴阳二毒伤寒。或因下早亡阳。或致结伏胸膈。四肢厥冷。脉息俱
无。心燥如火。或因冷物伤脾。夹脐注痛。生硬入胃。中满痞塞。及发潮热。并治翻胃
哕逆。霍乱吐泻。小肠 癖。胁肋气痛。但是阴阳不顺。恶候伤寒。并治之。每服一
粒。炭火内 通赤。良久取出。放冷。细研如粉。米饮一盏。煎至七分。温服。不拘
时。隔半时辰。再服。甚效。兼
金星石 银星石 代赭石 太阴玄精石 云母石（白色成片子者） 禹余粮石 桂府滑
石
（各一两） 寒水石（吉州者一两半） 不灰木（色青黑性软者一两） 上同入瓷瓶子内。
炭火半
秤。 。火耗一半。取出放冷。研为细末。糯米粥为丸。如弹子大。候干。根据前法服。寒水
石。南人谓之软石膏。一方加麦饭石。（一两）
归魂散（圣济总录）治阴阳二毒。不省人事。
石膏（八两） 寒水石（四两） 附子（炮裂去皮脐三两）阳起石（三两同石膏寒水石
三味捣
细研为末和入新罐内 一伏时以纸铺地出火毒入四味药） 干姜（炮） 麻黄（去节各一两）
杏仁（二七枚去皮尖双仁炒研） 上捣研令匀。瓷盒盛。冷水调下二钱匕。
霹雳散（一名黑散子）治阴格阳。烦躁。不饮水。
用附子一枚。炮熟取出。用冷灰焙。细研。入真腊茶二大钱。和匀。为细末。每服分作
二服。水一盏。煎至六分。临熟入蜜半匙。放温。或冷服之。须臾燥止得睡。汗出即瘥。
黑龙丹 治阴阳二毒伤寒。
用舶上硫黄一两。以柳木槌。研三两日。巴豆一两。和壳。记个数。用二升铛子一口。
先安硫黄铺铛底。次安巴豆。又以硫黄盖之。酽醋半斤以来浇之。盏子盖合令紧蜜。更以湿
纸。周回固济缝。勿令透气。缝纸干。更以醋湿之。文武火熬。常着人守之。候里面巴豆作
声。数已半为度。急将铛子离火。便入臼中。急捣令细。再以少米醋。并蒸饼少许。再捣。
令冷。可丸如鸡头大。若是阴毒。用椒四十九粒。葱白二茎。水一盏。煎至六分。服一丸。
阳毒。用豆豉四十九粒。葱白二茎。水一盏同煎。吞一丸。不得嚼破。患经五六日。方可服
之。食前吃。切在度其病势。可下即与。虽及日数。病未传入。或未及其日。病先在脏。亦
不可拘执矣。有孕妇人亦许服。或吐或泻为候。不可吃热食。或觉心头空。以温白粥。或服
调气汤散补之。欲辨阴阳二毒之病者。但始得病。惟看手足指冷者。是阴。不冷气和者。是
阳。若冷至指节二三寸者。病轻。若冷至肘膝。为病难理。阴阳毒病。亦无常也。或初病便
有毒。或服药经五六日以上。或十余日后不瘥。变成其毒者。其候身重背强。咽喉痛。饮食
不下。毒瓦斯攻心。心腹烦疼。气促。四肢厥逆。呕吐。体如被打。面目青而体冷者。阴证也。
阳毒则不然。面目赤。身壮热。或便脓血。喉疼。生斑点如锦纹是也。合时。忌妇人、猫、
狗见。
破证夺命汤 治阴阳二毒伤寒。证候不明。下药错误。致患人困重垂死。七日以
后。十日以来。可服此。传者云。千不失一。只一服。不超时见效。汗自鼻上出尽是
应。（方见破证夺命散）
丹砂丸（出活人书）治伤寒阴阳二毒。相伏危恶形证。
硝石（半两） 太阳石 舶上硫黄 水银 太阴石 玄精石（各一两） 上为末。先用
无油
铫子。以文武火炒。下诸药末。令一如灰色。研如粉面。生姜自然汁。浸蒸饼为丸。如绿豆
大。每服五丸。龙脑、牛黄、生姜、蜜水下。压躁也。若阳毒。枣汤下。阴毒。任汤下。不
得于屋底炒。一方无太阳石。
夺命丹（出王氏博济方）治阴阳二毒。气冲心。
朱砂（二两） 金箔（八十片） 腻粉（半两） 巴豆（八十个纸裹出油） 黄蜡（二
两） 上为
末。炼蜡为丸。如鸡头大。如有患者。以腻粉一钱。米饮一盏调下。如人行一里以来。其药
动下恶物。如药在其中。取出。掘一地坑。埋三伏时取出。除却上面黑物。以麝香裹养之。
如更用时。擘为两处。重为丸。一粒可疗五七人。神圣之功。卒难叙述。
青蒿散 治阴阳二毒伤寒。及肢体疼倦。\x
上用青蒿。八九月候成实。多采。去枝梗。以童子小便。浸三两日。漉起。酢干日晒。
为末。每服三钱。水一盏。乌梅一个。同煎七分。温服。
Yin qi flourishing and sudden collapse of Yang qi result in Yin Du (Yin Toxin). If Yang qi flourishes and sudden collapse of Yin qi occurs, it results in Yang Du (Yang Toxin). Generally speaking, when Yin and Yang separate and collapse, only profuse sweating can restore the healthy Qi. When all six pulses are surging and large, or deep, and feel large but not very rapid upon palpation, it is not a Yin syndrome. For Yang Du, the pulse should be wiry, surging, and rapid. For Yin Du, the pulse is deep, fine, and rapid. In Yang disease, the body is hot without sweat; in Yin disease, the body is cold with sweat. Qibo stated: "When Yang prevails, the body becomes hot, the interstices close, breathing becomes coarse causing difficulty in bending and stretching, and heat persists without sweat. When Yin prevails, the body becomes cold with sweat, frequent shivering and chills occur, cold leads to extremity reversal." This condition cannot be treated with ordinary methods. The *Jingui Yaolue* discusses Yang Du as a disease presenting with a red face, mottled spots like brocade patterns, sore throat, and expectoration of pus and blood. It is treatable within five days, but untreatable after seven days. Yin Du presents with a bluish-green complexion and face, body pain resembling being beaten, and sore throat; its prognosis for life and death is the same as Yang Du. The *San Yin Fang* states: Patients suffer from heavy head and stiff neck, strong numbness of skin and flesh, or accumulation forming nodules starting from the sides of the throat and neck. Heat toxin spreads into the skin and muscle layers, dispersing upwards into the hairline and downwards through the temples, with hidden heat that does not break off. This disease is named Huang Rou Sui (Yellow Flesh Following). Occurring on the eighteen Wu-Ji days of each season, the disease arises from the conflict between Taiyang and Yangming. Cold-dampness is disordered, and joints are obstructed. If the Fu organs are deficient, there is strong numbness of skin and flesh; if the Zang organs are excess, toxin-heat spreads to the skin. It also states: Patients have internal heat and external cold, desire to keep warm by fire, yet paradoxically crave drinking. Lower back pain feels as if breaking, or chest and hypochondriac cutting pain like knife stabs, preventing turning. Heat builds up internally. Taking too much cold medicine causes severe diarrhea. This disease is named Hei Gu Wen (Black Bone Warmth). Originating in the winter months, the source comes from the struggle between Foot Taiyang and Shaoyin. Accumulation and blockage occur. If the Fu organs are deficient, they are injured by Yin Du, resulting in internal heat and external cold. If the Zang organs are excess, they are damaged by Yang Du, resulting in intense fever. It also states: Patients have fever, lower back pain with stiffness and urgency, legs curled and unable to extend, waist feeling as if breaking, flowers dancing before eyes, or alternating chills and fever. The two tendons in the neck are pulled and cannot bend or stretch; the neck is straight and back is stiff. Eyes are red and yellow, wanting to turn, and the body twists to the side. This disease is named Qing Jin Qian (Green Tendons Pulling). Originating in the spring months, the source comes from Jueyin entering Shaoyang. Shaoyang qi begins to emerge, while Shaoyin qi begins to decline. Yin and Yang are depressed in the interstices, and the Fu and Zang organs are harmed, leading to generation of disease. If the Fu organs are deficient, they are injured by Yin pathogenic factors, thus causing fever. If the Zang organs are excess, [the disease] is named Chi Mai KT (Red Vessels KT). Occurring in the summer months, the disease arises from the struggle and stagnation of Shaoyin and Taiyang qi. Ying and Wei circulation is blocked, causing pain and swelling in skin and flesh. Taiyang activates, and the excessive pathogenic qi of Shaoyin acts destructively, so the Zang and Fu organs receive epidemic diseases according to the time. If the Fu organs are deficient, they are injured by Yin pathogenic factors, causing chills. If
Formulas
Treatment for Qing Jin Qian (from *San Yin Fang*): Liver Zang-Fu Warm Disease, Yin-Yang Du. Gallbladder Fu deficiency, injured by Yin pathogenic factors. Stiffness and urgency of waist and hypochondrium, legs curled and unable to extend. Chai Hu (5 liang, remove seedlings), Fu Ling, Zhi Zi Ren, Ban Xia (washed with decoction), Da Qing (each 3 liang), Gui Xin, Zhu Ru, Xiang Chi, Gan Cao (formula incomplete).
Another Formula (from *San Yin Fang*): Liver Zang-Fu Warm Disease, Yin-Yang Du. Liver Zang excess, injured by Yang Du. Shivering aversion to cold, slight fever. Double tendons outside the neck... Xuan Shen (1 liang), Xi Xin (2 liang), Zhi Zi Ren, Huang Qin, Sheng Ma, Mang Xiao (each 3 liang), Shi Gao (8 liang). Pound and sieve into powder. Take 5 qian per dose. Add 2 zhan of water, 3 leaves of Che Qian Cao, 7 slices of Dan Zhu Ye. Decoct to 70%. Strain. Take on an empty stomach.
Treatment for Chi Mai KT (from *San Yin Fang*): Heart Zang-Fu Warm Disease, Yin-Yang Du. If Fu deficiency, overwhelmed by Yin pathogenic factors. Pulse is hurried. Body trembles and cannot control itself. Color... Fu Ling, Ren Shen, Jie Geng (each 3 fen), Gan Cao (1.5 liang), Bai Zhi, Qing Pi (each 1 liang), Gan Jiang (roasted, half liang). Pound and sieve into powder. Take 5 qian per dose. Add 2 zhan of water. Decoct to 70%. Strain. Take before meals.
Another Formula (from *San Yin Fang*): Heart Zang-Fu Warm Disease, Yin-Yang Du. Heart Zang excess, injured by Yang Du. Internal heat, dry mouth, cracked tongue, throat obstruction, hoarse voice. Tian Men Dong (remove heart), Mai Men Dong (remove heart), Che Qian Zi (fried), Zhi Zi Ren, Huang Qin, Sheng Ma, Gan Cao (roasted), Han Shui Shi (formula incomplete).
Treatment for Huang Rou Sui (from *San Yin Fang*): Spleen Zang-Fu Warm Disease, Yin-Yang Du. Stomach Fu deficiency, injured by Yin pathogenic factors. Heavy head, stiff neck, strong numbness of skin and flesh. Nong Po (roasted with ginger juice, 1.5 liang), Bai Zhu, Chen Pi (half amount each), Gan Jiang (roasted), Zi Su, Gan Cao (roasted), Ban Xia (washed with decoction, each 3 fen). Pound and sieve into powder. Take 5 qian per dose. Add 2 zhan of water. Decoct to 70%. Strain. Take before meals.
Another Formula (from *San Yin Fang*): Spleen Zang-Fu Warm Disease, Yin-Yang Du. Spleen Zang excess, injured by Yang Du. Accumulated heat forming nodules, starting from the sides of the throat and neck, spreading toxin... Ge Gen, Cang Zhu (soaked in rice water), Sheng Ma, Bai Zhi, Jie Geng, Qing Pi (each 1 liang), Da Huang (half liang). Pound and sieve into powder. Take 5 qian per dose. Add 2 zhan of water. Decoct to 70%. Strain. Take before meals.
Treatment for Bai Qi Li (from *San Yin Fang*): Lung Zang-Fu Warm Disease, Yin-Yang Du. Taiyang Fu deficiency, injured by Yin pathogenic factors. Alternating chills and fever, upward rebellious Qi, cough and wheezing, large intestine undigested food diarrhea, color bright white. Bai Zhu, Ren Shen (each 1 liang), Gan Jiang (roasted), Mai (fried, each 3 fen), Bai Fu Ling, Wu Wei Zi, Rou Dou Kou, Cao Guo, Wu Mei, Gan Cao (roasted, half liang each). Pound and sieve into powder. Take 5 qian per dose. Add 2.5 zhan of water. Decoct to 70%. Strain. Take before meals.
Another Formula (from *San Yin Fang*): Lung Zang-Fu Warm Disease, Yin-Yang Du. Lung Zang excess, injured by Yang Du. Body heat, macules on skin, asthma craving drink. Zi Wan Rong (1 liang), Zhi Zi Ren, Sheng Ma, Qian Hu (each 3 fen), Shi Gao (half liang), Ting Li (fried, 1 fen), Xing Ren (remove skin and tip), Gan Cao (roasted, half liang each). Pound and sieve into powder. Take 5 qian per dose. Add 2 zhan of water. Decoct to 70%. Strain. Take before meals.
Treatment for Hei Gu Wen (from *San Yin Fang*): Kidney Zang-Fu Warm Disease, Yin-Yang Du. Bladder Fu deficiency, injured by Yin pathogenic factors. Internal heat, external cold, vexation and thirst craving drink. Fu Zi (roasted, remove skin and umbilicus), Fu Ling (each 1 liang), Shan Zhu Yu, Xi Xin, Shan Yao, Ze Xie (each half liang), Ma Huang (3 fen), Xing Ren (remove skin and tip, 1 fen). Pound and sieve into powder. Take 5 qian per dose. Add 2 zhan of water. Decoct to 70%. Strain. Take before meals.
Another Formula (from *San Yin Fang*): Kidney Zang-Fu Warm Disease, Yin-Yang Du. Kidney Zang excess, injured by Yang Du. Cutting pain in waist and hypochondrium, inability to turn, constipation of urine and stool, abdominal distension, severe diarrhea after eating cold food, dark blackish color. Wu Zhu Yu, Hei Qian Niu (fried), Tao Ren (remove skin and tip), Bi Xie, Du Zhong (remove skin, cut, roast with ginger juice until silk breaks), Da Huang (steamed, equal parts). Pound and sieve into powder. Take 5 qian per dose. Add 2 zhan of water. Decoct to 70%. Strain. Take before meals.
Treatment for Liver Zang-Fu Warm Disease, Yin-Yang Du: Pulling of double tendons in neck and back, chills first then fever, stiff and urgent waist, curling, flowers dancing before eyes. (From *Qian Jin Fang*). Gui Xin (1 liang), Bai Zhu, Mang Xiao, Da Qing, Zhi Zi (each 3 liang), Chai Hu (5 liang), Shi Gao, Sheng Jiang (each 8 liang), Sheng Di Huang, Xiang Chi (each 1 sheng). Chop. Boil in 9 sheng of water to obtain 3 sheng. Divide into three doses.
Treatment for Heart Zang-Fu Warm Disease, Yin-Yang Du: Unstable trembling,惊动 (startle/movement). (From *Qian Jin Fang*). Da Qing, Huang Qin, Zhi Zi, Zhi Mu, Mang Xiao (each 3 liang), Ma Huang (4 liang), Xuan Shen (6 liang), Shi Gao, Sheng Ge Gen (each 8 liang), Sheng Di Huang (cut, 1 sheng). Chop. Boil in 9 sheng of water to obtain 3 sheng. Strain. Add Mang Xiao. Divide into three doses.
Treatment for Spleen Zang-Fu Warm Disease, Yin-Yang Du: Heavy head, stiff neck, numbness of skin and flesh, hidden rising nodules. (From *Qian Jin Fang*). Da Qing, Ling Yang Jiao, Sheng Ma, She Gan, Mang Xiao (each 3 liang), Zhi Zi (4 liang), Han Shui Shi (6 liang), Xuan Shen (8 liang). Chop. Boil in 7 sheng of water to obtain 3 sheng. Divide into three doses.
Treatment for Lung Zang-Fu Warm Disease, Yin-Yang Du: Continuous coughing without voice cessation, vomiting and rebellion. (From *Qian Jin Fang*). Ma Huang, Zhi Zi, Zi Wan, Da Qing, Xuan Shen, Ge Gen (each 3 liang), Gui Xin, Gan Cao, Xing Ren, Qian Hu (each 4 liang), Shi Gao (8 liang). Chop. Boil in 9 sheng of water to obtain 3 sheng. Divide into three doses.
Treatment for Kidney Zang-Fu Warm Disease: Body and face feel like pricks, waist feels as if breaking, internal injury by heat toxin. (From *Qian Jin Fang*). Yin Chen Hao, Zhi Zi, Mang Xiao (each 3 liang), Ku Shen, Sheng Ge (each 4 liang), Sheng Di Huang, Shi Gao (each 8 liang), Cong Bai, Chi (1 sheng). Chop. Boil in 9 sheng of water to obtain 2.5 sheng. Add Xiao (Mang Xiao). Divide into three doses.
Da Jiao Tai Dan: Treats Yin-Yang Er Du Shang Han (Cold Damage due to Yin-Yang Two Toxins). Caused by premature purgation leading to loss of Yang, or knotting and伏 (hiding) in chest and diaphragm. Cold limbs, no pulse. Heart dry as fire. Or cold food injuring Spleen, pain radiating from navel, hard food entering stomach, fullness and obstruction in middle jiao, tidal fever. Also treats Fan Wei (rebellious stomach), Yue Ni (hiccups), Huo Luan (cholera-like vomiting and diarrhea), Xiao Chang Ji Ju (abdominal masses), Qi pain in hypochondrium. Any disharmony of Yin and Yang, malignant signs of Shang Han, are all treated. Take one pill. Roast in charcoal fire until red hot. Remove after a while, let cool, grind finely into powder. Mix with one zhan of rice drink, decoct to 70%. Take warm. No fixed time. Repeat after half a chen (two hours). Very effective. Ingredients: Jin Xing Shi, Yin Xing Shi, Dai Zhe Shi, Tai Yin Xuan Jing Shi, Yun Mu Shi (white sheet-like), Yu Yu Liang Shi, Gui Fu Hua Shi (each 1 liang), Han Shui Shi (from Jizhou, 1.5 liang), Bu Hui Mu (green-black, soft, 1 liang). Put together in a porcelain bottle. Roast in charcoal fire until half consumed. Remove, let cool, grind to fine powder. Make pills with glutinous rice porridge, size of a bullet. Dry. Take according to previous method. Han Shui Shi is called Soft Shi Gao by Southerners. Another formula adds Mai Fan Shi (1 liang).
Gui Hun San (from *Sheng Ji Zong Lu*): Treats Yin-Yang Er Du, unconsciousness. Shi Gao (8 liang), Han Shui Shi (4 liang), Fu Zi (roasted, split, remove skin and umbilicus, 3 liang), Yang Qi Shi (3 liang). Pound the three ingredients (Shi Gao, Han Shui Shi, Yang Qi Shi) finely into powder, mix in a new jar. Lay paper on ground to remove fire toxicity for one fu (approx. 2 hours). Add four other medicines: Gan Jiang (roasted), Ma Huang (remove nodes, each 1 liang), Xing Ren (14 seeds, remove skin/tip, double kernel, roast and grind). Pound and grind evenly. Store in porcelain box. Mix with cold water, take 2 qian bi.
Pi Li San (also known as Hei San Zi): Treats Yin blocking Yang, irritability, no desire to drink. Use one Fu Zi, roast thoroughly, remove. Roast in cold ash. Grind finely. Add Zhen La Cha (true Lab tea) 2 da qian. Mix evenly, grind to fine powder. Divide into two doses per administration. Add 1 zhan of water, decoct to 60%. Just before finishing, add half spoon of honey. Let cool or take warm. Soon dryness stops, sleep ensues, sweat appears and recovery follows.
Hei Long Dan: Treats Yin-Yang Er Du Shang Han. Use 1 liang of Bo Shang Liu Huang. Grind with willow wood pestle for 2-3 days. 1 liang of Ba Dou, keep shell, count number. Use a 2-sheng pot. First place Liu Huang at bottom, then Ba Dou, cover with Liu Huang. Pour 0.5 jin of strong vinegar. Cover tightly with lid, seal seams with wet paper to prevent air leakage. When paper dries, moisten again with vinegar. Simmer with mild and strong fire, always watch. When Ba Dou inside makes sound and count is halved, immediately remove pot from fire. Put in mortar, pound finely. Add small amount of rice vinegar and steamed cake, pound again. Cool. Make pills size of chicken head. For Yin Du: use 49 Sichuan peppercorns, 2 stalks of Cong Bai, 1 zhan of water, decoct to 60%. Take one pill. For Yang Du: use 49 Chi Dou, 2 stalks of Cong Bai, 1 zhan of water, decoct together. Swallow one pill, do not chew. Can take after illness has lasted 5-6 days. Take before meals. Must assess disease trend; if suitable for purgation, give it. Even if days have passed, if disease hasn't transmitted, or if before days have passed but disease is already in Zang, do not rigidly adhere. Pregnant women may also take. Vomiting or diarrhea serves as indicator. Do not eat hot food. If feeling empty in heart, use warm white porridge or Tiao Qi Tang/San to supplement. To distinguish Yin-Yang Er Du: At onset, check if finger tips are cold. Cold indicates Yin; warm and harmonious indicates Yang. Cold up to 2-3 cun of finger joints means mild disease. Cold up to elbows and knees means difficult to treat. Yin-Yang Du disease is not constant. Some have toxin from start, some develop toxin after 5-6 days or 10+ days of medication without cure. Signs: heavy body, stiff back, sore throat, inability to eat, toxin attacking heart, vexation and pain in heart/abdomen, shortness of breath, extremity reversal, vomiting, body feels beaten, blue-green face and cold body indicate Yin syndrome. Yang Du is different: red face, high fever, pus/blood in stool, sore throat, spots like brocade pattern. During preparation, avoid exposure to women, cats, dogs.
Po Zheng Duo Ming Tang: Treats Yin-Yang Er Du Shang Han. Unclear symptoms, incorrect use of purgatives, causing patient to be critically ill and near death. After 7 to 10 days, this can be taken. Legend says: 1 in 1000 misses. One dose brings effect within time. Sweat from nose is response. (Formula see Po Zheng Duo Ming San).
Dan Sha Wan (from *Huo Ren Shu*): Treats Shang Han Yin-Yang Er Du, conflicting dangerous signs. Xiao Shi (half liang), Tai Yang Shi, Bo Shang Liu Huang, Shui Yin, Tai Yin Shi, Xuan Jing Shi (each 1 liang). Make into powder. Use oil-free yinzi. Stir-fry with mild/strong fire. Add drug powders. Fry until gray color. Grind like flour. Soak steamed cake in fresh ginger juice. Make pills size of mung bean. Take 5 pills per dose. Take with Long Nao, Niu Huang, Ginger juice, Honey water to suppress restlessness. For Yang Du, take with Jujube decoction. For Yin Du, take with Ren Shen decoction. Do not fry under roof. Another formula omits Tai Yang Shi.
Duo Ming Dan (from *Wang Shi Bo Ji Fang*): Treats Yin-Yang Er Du, Qi rushing to heart. Zhu Sha (2 liang), Jin Bo (80 pieces), Ni Fen (half liang), Ba Dou (80 seeds, paper-wrapped to remove oil), Huang La (2 liang). Make into powder. Refine wax to make pills size of chicken head. For patients, mix 1 qian Ni Fen with 1 zhan rice drink, take down. Within walking distance of 1 li, medicine moves out evil matter. If medicine remains inside, dig a pit, bury for 3 fu times. Remove, discard black top layer, wrap with She Xiang to nourish. If used again, split into two, remake pills. One pill can treat 5-7 people. Divine efficacy, hard to describe fully.
Qing Hao San: Treats Yin-Yang Er Du Shang Han, and limb pain/fatigue. Use Qing Hao. Harvest in Aug/Sept when mature. Pick much, remove stems. Soak in child's urine for 2-3 days. Drain, dry with vinegar and sun. Grind to powder. Take 3 qian per dose. Add 1 zhan water, 1 Wu Mei. Decoct to 70%. Take warm.