徐仲光治一儿，患血热痘，先用寒凉，芩、连、犀角，起发灌浆，头面身背俱脓，但两腿面凹陷不起。
用参、 托之，反见热渴躁烦，大便溏泄多次，咽喉肿痛。改用清咽利膈，山豆根、麦冬、川贝、桔梗、元参、
防风、僵蚕、山甲、当归、白芍、红花、生地、山楂、陈皮、蚯蚓、牛蒡、川连、黄芩、甘草而愈。
一儿痘后，咽痛壅塞不通，此余毒留于心肺，邪热不泄，风痰壅盛。先以桐油探吐，服驼原散、甘桔汤、
连翘、牛蒡、射干、元参而愈。
一儿痘后，真阴不足，二火上行，咽喉肿痛。有以寒凉治者，愈而复肿。原其火为寒郁，先以附子理中汤
驱其寒，次宜壮水之主，六味地黄丸加知母、麦冬、元参治其本，外吹葛槿散而愈。
一儿痘后，脾胃不足，阴火上炎，咽喉肿痛，以四君子加甘、桔、知、柏、川连、牛蒡而愈。
一儿痘后，咽喉成疔，以柴、葛、地龙、蜈蚣等分煎成，加犀角磨汁和服而愈。
万密斋治马氏子，五岁，痘不起发。曰∶此顺痘也。毒甚者，则头面肿，毒微者，则头面不肿，非不起发
也。又呼咽痛。曰∶此痘家常病，喜喉舌无疮，颈项间痘稀，不足怪也。以甘桔汤加牛蒡子煎，细细咽之，咽
痛即止。
万密斋媳李氏，年十八，痘成脓时，经水忽行，下血块且多，未逾日，猝失音。问之，但摇头垂泪。凡痘
带黑归肾，宜有猝失音之症。今已成脓，饱满红润，何以有此逆症？思之良久乃得之，经云∶妇人重身，九月
而喑者，少阴之脉不荣于舌也。手少阴者，心也。心主血，诸疮皆属于心。疮毒之火，内起于心，迫血下行，
故经血来也。舌者心之苗，血去则心虚不能上荣于舌，故舌萎缩而猝失音也。乃以生脉散去五味子，加当归、
生地服之，顷之愈。后以十全大补汤调理而起。
萧氏子，三岁出痘，将靥时，忽失音，啼哭有声，但言语重浊不清亮。曰∶此肺热也。以甘桔清金散服之
而安。
Xu Zhongguang treated a child suffering from blood-heat type variola (smallpox). Initially, cold and cool-natured herbs (such as Huangqin/Coptis Rhizome, Lianlian/Coptis Chinensis Rhizome, Xijiao/Rhinoceros Horn) were used to promote the eruption and suppuration of the pustules. Consequently, pus formed on the head, face, trunk, and back, but the surfaces of both legs remained sunken and did not rise.
After using Ginseng-based formulas to support the expulsion of toxins, the child instead developed heat sensation with thirst, restlessness, frequent loose stools, and sore throat with swelling. The treatment was then changed to clearing the pharynx and benefiting the diaphragm, using Shandougen/Sophora Flavescens Root, Maidong/Ophiopogon Tuber, Chuanbeimu/Fritillaria Cirrhosa Bulb, Jiegeng/Platycodon Root, Xuanshen/Scrophularia Root, Fangfeng/Saposhnikovia Root, Jiangcan/Bombyx Batryticatus, Shanji/Pangolin Scales, Danggui/Angelica Sinensis Radix, Baishao/Paeonia Lactiflora Radix, Honghua/Safflower, Shengdihuang/Rehmannia Glutinosa Root, Shanzha/Crataegus Fruit, Chenpi/Tangerine Peel, Dilong/Earthworm, Niubangzi/Arctium Fruit, Chuanlian/Coptis Rhizome, Huangqin/Scutellaria Root, and Gancao/Licorice Root, resulting in recovery.
Another child suffered from sore throat and obstruction after variola, caused by residual toxins lingering in the Heart and Lung, unexpelled pathogenic heat, and abundant wind-phlegm. Tongyou (Tung Oil) was first used for emesis induction, followed by Tuoyuan San, Ganjie Tang, Lianqiao/Forsythia Fruit, Niubangzi, Yeyan/Belamcanda Rhizome, and Xuanshen, leading to recovery.
A third child, post-variola, had insufficient True Yin with ministerial fire ascending, causing sore throat and swelling. Treatment with cold herbs initially reduced swelling but led to recurrence upon cessation. Upon analysis, the fire was determined to be constrained by cold. Fuzi Lizhong Tang was first administered to dispel cold, followed by Liuwei Dihuang Wan (Six-Ingredient Rehmannia Pill) supplemented with Zhimu/Anemarrhena Rhizome, Maidong, and Xuanshen to tonify the root (strengthening Water to control Fire), along with external application of Gejin San to the throat, resulting in recovery.
A fourth child, post-variola, presented with spleen and stomach deficiency and yin fire flaming upward, causing sore throat. Si Jun Zi Tang (Four Gentlemen Decoction) supplemented with Gancao, Jiegeng, Zhimu, Huangbai/Phellodendron Bark, Chuanlian, and Niubangzi resulted in recovery.
A fifth child developed a carbuncle in the throat post-variola. Chaihu/Bupleurum Root, Gegen/Pueraria Root, Dilong, and Wugong/Scolopendra were decocted in equal parts, mixed with ground Xijiao/Rhinoceros Horn juice, and ingested, leading to recovery.
Wan Mizhai treated Ma's son, aged five, whose variola failed to erupt. He stated: This is a favorable course of variola. When toxins are severe, the head and face swell; when toxins are mild, they do not swell, which does not indicate failure to erupt. The child also complained of sore throat. He remarked: This is a common condition in variola cases. As long as there are no sores in the throat and tongue, and the rash is sparse around the neck, there is no cause for alarm. Ganjie Tang supplemented with Niubangzi was decocted and swallowed slowly, stopping the sore throat immediately.
Wan Mizhai's daughter-in-law, Li, aged eighteen, experienced sudden onset of loss of voice (aphonia) less than a day after her menstruation began during the suppuration stage of variola, accompanied by heavy bleeding and clots. She could only shake her head and shed tears. It is said that when variola turns black and relates to the Kidney, sudden aphonia should occur. However, her pustules were full, plump, and ruddy-red, making this an adverse sign. After deep reflection, he recalled the Classic stating: "Women pregnant for nine months may lose their voice because the Shaoyin meridian fails to nourish the tongue." The Hand-Shaoyin meridian belongs to the Heart. The Heart governs Blood, and all sores and ulcers belong to the Heart. The fire of the toxin originated internally in the Heart, forcing blood downward, hence the menstrual flow. The tongue is the sprout of the Heart; loss of blood leads to Heart deficiency, preventing nourishment from reaching the tongue, causing tongue atrophy and sudden aphonia. Shengmai San (Generate the Pulse Powder) without Wuweizi/Schisandra Fruit, supplemented with Danggui and Shengdihuang, was administered, resulting in rapid recovery. Subsequently, Shiquan Dabu Tang (Complete Great Tonifying Decoction) was used for regulation and convalescence.
Xiao's son, aged three, developed variola. Just as the lesions were about to crust over, he suddenly lost his voice. Although he could cry out, his speech was hoarse and unclear. He diagnosed this as Lung heat and prescribed Ganjie Qingjin San (Ganjie Clear Metal Powder), which brought relief.