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Jue syndrome (Cold Extremities Syndrome) has both Yin and Yang types. When the disease first begins, if the body is hot, and after three or four days, the heat pathogen gradually deepens, resulting in constipation, yellowish-red urine, or delirious speech accompanied by fever, this is Yang Jue (Yang Cold Extremities). If upon onset the body is not hot, and after three or four days, Yang Qi gradually diminishes, leading to soft and loose stools, clear and white urine, or low-voiced speech without fever, this is Yin Jue (Yin Cold Extremities). These two presentations are often confused because both present with a Chen pulse (Deep Pulse). However, in Yang Jue with a Deep pulse, the pulse should be forceful; in Yin Jue with a Deep pulse, the pulse should be weak. In Yang Jue, the fingertips may occasionally become warm; in Yin Jue, the fingertips are constantly cold. Zhang Zhongjing stated: "In Shanghan (Cold Damage), if Jue occurs on the second or third day, or fourth or fifth day, it must be accompanied by fever. Fever preceding Jue implies that the deeper the Jue, the deeper the internal heat; this requires purgation, suitable for Chengqi Tang." He also stated: "In Shanghan, if the pulse is slippery and there is Jue, there is heat inside; Baihu Tang should govern it." Zhang Zhongjing further stated: "In Shanghan, if there is diarrhea with undigested food, interior cold with exterior heat, cold extremities, and a faint pulse, this indicates interior cold. Sweating accompanied by Jue is similar." He also said: "In Yin diseases, if there is diarrhea and a faint pulse, there is interior cold; Baitong Tang should govern it." Another method involves using Baitong Tang plus Pig Bile when there is no pulse and diarrhea persists, due to accompanying dry throat and irritability. The above conditions are acute, or even extremely acute, and frequently present with such symptoms.

The direct pathway of the Foot-Shaoyin Kidney Meridian ascends through the liver and diaphragm into the lungs, connecting to the root of the tongue. The Kidney dislikes dryness; therefore, thirst and a desire to drink occur. The Classics state: "Dry mouth and tongue with thirst, combined with both Cun (Inch) and Chi (Cubit) pulses being Deep, indicates that the Kidney is affected by Heat Pathogens, constituting a Yang syndrome, which requires purgation." Dry mouth and tongue in Yin syndromes are not caused by Heat Pathogens invading the Kidney Meridian, but rather result from individuals indulging in desires, depleting Essence and Qi, causing the True Water to dry up and Yuan Qi (Original Qi) to escape from within Yang (represented by the Yang line in the Kan trigram). Dietary injury from cold foods transforms into Withered Yin, where Yang dissipates internally; such cases may not feel thirsty. However, if Yang wanders externally, there will certainly be thirst and a desire to drink. Yet, those desiring to drink prefer hot water over cold water. Even if some attempt to drink cold water, if they cannot tolerate it but fail to restrain themselves and drink excessively, complications arise. For those with dry tongues desiring cold water, suppressing this urge and providing hot water brings relief in the chest once consumed, resolving the thirst immediately. If one mistakes this thirst for Heat, can hot water resolve it? Not only will it not resolve the thirst, but the heat will intensify. Thus, we know this is a Yin syndrome; what doubt remains!