脉沉为在里而反发其汗则津液越出大便难表虚里实久则谵语也(论见谵语)脉浮紧者法当身疼痛宜以汗解之假令尺
中迟者不可发汗何以知之以荣气不足血少故也(活人云先以小建中汤加黄 如尺脉尚迟再作一剂却服桂枝柴胡二越婢一
汤其汤分小剂和解之愈)
许 一乡人邱生者病伤寒发热头疼烦渴脉虽浮数而无力尺以下迟而弱予曰此虽麻黄证而尺迟弱仲景云尺中迟者荣
气不足血气微少未可发汗予于建中汤加当归黄 令饮翌日脉尚尔其家煎迫日夜督发汗药几不逊矣余忍之但用建中调荣
而已至五日尺部方应遂投麻黄汤啜二服发狂须臾稍定略睡已中汗矣信知此事诚难仲景虽云不避晨夜即宜便治医者亦须
顾其表里虚实待其时日若不循次第临时得安损亏五脏以促寿限亦何足贵哉南史载范云病伤寒恐不得预武帝九锡之庆召
徐文伯诊视以实恳之曰可便得愈乎文伯曰便瘥甚易但恐二年后不复起耳云曰朝闻道夕死犹可况二年乎文伯以火烧地布
桃叶设席置云于其上顷刻汗解扑以温粉翼日果愈云甚喜文伯曰不足喜也后二年果卒夫取汗先期尚促寿限况罔顾表里不
待时日便欲速效乎每见病家不耐病未三四日昼夜促汗医者随情顺意鲜有不败事者予故书此以为戒
少阴病脉细沉数病为在里不可发汗少阴病脉微不可发汗亡阳故也脉濡而弱弱反在关濡反在巅微反在上涩反在下微
则阳气不足涩则无血阳气反微中风汗出而反躁烦涩则无血厥而且寒阳微发汗躁不得眠动气在右不可发汗发汗则衄而渴
心苦烦饮即吐水动气在左不可发汗发汗则头眩汗不止筋惕肉 动气在上不可发汗发汗则气上冲正在心端动气在下不可
发汗发汗则无汗心中大烦骨节苦疼目连恶寒食则反吐谷不得前咽中闭塞不可发汗发汗则吐血气微绝手足厥冷欲得倦卧
不能自温诸脉得数动微弱者不可发汗发汗则大便难腹中干(一云小便难胞中干)胃躁而烦其形相象根本异源脉濡而弱弱
反在关濡反在巅弦反在上微反在下弦为阳运微为阴寒上实下虚意欲得温微弦为虚不可发汗发汗则寒栗不能自还咳者则
剧数吐涎沫咽中必干小便不利心中饥烦 时而发其形似疟有寒无热虚而寒栗咳而发汗蜷而苦满腹中复坚厥脉紧不可发
汗发汗则声乱咽嘶舌萎声不得前诸逆发汗病微者难瘥剧者言乱目眩者死(一云谵言目眩睛乱者死)命将难全太阳病得之
八九日如疟状发热恶寒热多寒少其人不呕清便续自可一日二三度发脉微而恶寒者此阴阳俱虚不可更发汗也太阳病发热
恶寒热多寒少脉微弱者无阳也不可发汗咽喉干燥者不可发汗亡血不可发汗发汗则寒栗而振衄家不可发汗汗出必额上陷
脉急紧直视不能 不得眠汗家不可发汗发汗必恍惚心乱小便已阴疼宜禹余粮丸(方本阙)淋家不可发汗发汗必便血疮家
虽身疼痛不可发汗汗出则痉下利不可发汗汗出必胀满咳而小便利若失小便者不可发汗汗出则四肢厥逆冷伤寒一二日至
四五日厥者必发热前厥者后必热厥深者热亦深厥微者热亦微厥应下之而反发汗者必口伤烂赤伤寒脉弦细头痛发热者属
少阳少阳不可发汗伤寒头痛翕翕发热形象中风常微汗出自呕者下之益烦心懊 如饥发汗则致痉身强难以伸屈熏之则发
黄不得小便久则发咳唾太阳与少阳并病头项强痛或眩冒时如结胸心下痞硬者不可发汗太阳病发汗因致痉少阴病咳而下
利谵语者此被火气劫故也小便必难以强责少阴汗也少阴病但厥无汗而强发之必动其血未知从何道出或从口鼻或从目出
者是名下厥上竭最为难治
永类钤方云伤寒发汗有四难凡发热头疼有汗而非无汗恶风而非恶寒例发其汗汗不止为漏风间有发而为痉者此分外
证发汗之一难也至于发热头痛尺脉迟者为荣虚血少不可发汗发热头痛脉弦细属少阳不可汗汗则谵语此分脉发汗之二难
也动气在左不可汗汗则头眩汗不止则筋惕肉 动气在右不可汗汗则衄而渴心烦饮则吐水动气在上不可汗汗则气冲心动
气在下不可汗汗则无汗心烦骨节疼此分内证发汗之三难也春宜汗不可大发以阳气尚微冬不大汗以阳气伏藏汗之必吐利
口烂生疮此知时发汗之四难也
云 太阳证非头痛项强不可发汗非身热恶寒不可发汗非脉浮不可发汗
活 其脉微弱或尺脉迟者不可表其人当汗而衄血下血者不可表坏病者不可表妇人经水适来者不可表风温者不可表
湿温者不可表虚烦者不可表病患腹间左右上下有筑触动气者不可表太阳咽干鼻衄淋漓小便不利皆不当汗已经发汗不得
重发如无以上忌证虽经发汗邪气未尽亦当重发之当汗不汗则生黄其证为风寒所伤阳气下陷入内而与寒水上行于经络之
间本当发汗以彻其邪医失汗之故生黄也脾主肌肉四肢寒湿与内热相合故生黄也不当汗而汗为蓄血之证燥火也当益津液
为上而反汗以亡之其毒扰阳之极则侵阴也故燥血蓄于胸中也当汗而发汗过多腠理开泄汗漏不止故四肢急难以屈伸也
A deep pulse indicates the pathogen is in the interior; if sweating is induced in error, body fluids will escape excessively, leading to difficult defecation. The exterior becomes deficient while the interior becomes excess; over time, this may result in delirium (incoherent speech due to mental confusion). (See discussion under "Delirium".)
A floating and tight pulse typically presents with body pain and should be treated by inducing sweating. However, if the cun-guan-chi pulse at the chi position is slow, sweating must not be induced. How do we know this? Because Ying Qi (Nutritive Qi) is insufficient and blood is scant. (The *Liu Ren Shu* states: First administer Xiao Jian Zhong Tang (Minor Construct the Middle Decoction) added with Huangqi (Astragali Radix); if the chi pulse remains slow, administer another dose, then take Guizhi Tang (Cinnamon Twig Decoction), Chaihu Tang (Bupleurum Decoction), or Yuebi Tang (Ephedra and Magnolia Bark Decoction) in small doses to harmonize the condition, and the patient will recover.)
Xu Yishi once treated a fellow townsman, Qiu Sheng, who suffered from Shanghan (Cold Damage) with fever, headache, restlessness, and thirst. Although his pulse was floating and rapid, it was forceless, and the pulses below the guan position were slow and weak. I said: "Although this resembles a Mahuang Tang (Ephedra Decoction) pattern, the slow and weak chi pulse indicates, as Zhang Zhongjing stated, 'If the chi pulse is slow, Ying Qi is insufficient, and Qi and Blood are slightly depleted; sweating must not be induced.' I prescribed Jianzhong Tang (Construct the Middle Decoction) added with Danggui (Angelicae Sinensis Radix) and Huangqi (Astragali Radix) for him to drink. The next day, the pulse remained unchanged. His family prepared the decoction urgently, urging me day and night to induce sweating, leaving me little room to refuse. I endured their pressure, using only Jianzhong Tang to harmonize Ying and Wei (Defensive Qi). By the fifth day, the chi pulse finally became responsive. I then administered Mahuang Tang, two doses. After taking them, the patient went mad, but soon calmed down, slept briefly, and then sweated profusely, recovering completely. Indeed, I have come to know that this matter is truly difficult. Although Zhang Zhongjing said, 'Do not avoid morning or night, treat immediately,' physicians must also consider the exterior-interior deficiency-excess patterns and wait for the appropriate timing. If one does not follow the proper sequence and seeks temporary relief without regard for order, damaging the Zang-Fu organs and shortening life span, what value is there?"
The *History of the Southern Dynasties* records that Fan Yun contracted Shanghan and feared he would miss Emperor Wu's celebration of the Nine Bestowals. He summoned Xu Wenbo for diagnosis and asked earnestly, "Can I recover immediately?" Wenbo replied, "Recovering immediately is very easy, but I fear you will not rise again after two years." Yun said, "I heard the Way in the morning and could die content in the evening; how much more so for two years?" Wenbo heated the ground, spread peach leaves, set up a mat, and placed Yun upon it. In an instant, Yun sweated and recovered. Warm powder was applied. The next day, he indeed recovered and was very pleased. Wenbo said, "There is no need to be pleased." Two years later, Yun indeed died. This method of inducing sweating even accelerated his lifespan; how much more so for those who disregard exterior-interior deficiency-excess, do not wait for the proper time, and seek quick results? I often see patients' families unable to tolerate the illness, urging sweating day and night within three or four days. Physicians who comply with these desires rarely avoid failure. Therefore, I write this as a warning.
Shaoyin disease with a fine, deep, and rapid pulse indicates the pathogen is in the interior; sweating must not be induced. Shaoyin disease with a faint pulse cannot be treated with sweating because it leads to Yang collapse. A pulse that is soft and weak, where the weak quality is found at the guan position, the soft quality at the dian (cun) position, the faint quality at the upper part, and the choppy quality at the lower part. Faintness indicates insufficient Yang Qi; choppy indicates lack of Blood. If Yang Qi is faint, wind-stroke causes sweating followed by irritability; choppy indicates lack of Blood, leading to cold limbs and cold sensations. If Yang is faint, inducing sweating causes irritability and inability to sleep. If "moving qi" (abdominal pulsations) is on the right, sweating must not be induced; inducing sweating causes epistaxis and thirst, heart distress, and vomiting water after drinking. If moving qi is on the left, sweating must not be induced; inducing sweating causes dizziness, incessant sweating, tremors of muscles and twitching of flesh. If moving qi is above, sweating must not be induced; inducing sweating causes Qi rushing upward, centered at the heart. If moving qi is below, sweating must not be induced; inducing sweating causes absence of sweat, severe heart distress, painful bone joints, aversion to cold in the eyes, vomiting food after eating, obstruction of grain flow, and throat blockage. Sweating must not be induced; inducing sweating causes hematemesis, faint Qi, cold extremities, desire to lie down, and inability to warm oneself. Any pulse that is rapid-moving yet weak and faint should not be treated with sweating; inducing sweating leads to difficult defecation and dry abdomen (or difficult urination and dry bladder). Stomach dryness and irritability occur; although the manifestations seem similar, their origins differ. A pulse that is soft and weak, weak at guan, soft at cun, wiry at the upper part, and faint at the lower part. Wiry indicates Yang movement; faint indicates Yin cold. Upper excess and lower deficiency indicate a desire for warmth. Faint and wiry indicates deficiency; sweating must not be induced. Inducing sweating causes chills and inability to recover. Coughing worsens, with frequent spitting of saliva, dry throat, difficult urination, and hunger-like heart distress, occurring intermittently like malaria but with cold and no heat, presenting as deficiency with chills. Inducing sweating in coughing leads to curling up, abdominal fullness, and hardness. A tight Jue pulse cannot be treated with sweating; inducing sweating causes voice disorder, hoarseness, tongue flaccidity, and inability to speak. For all adverse conditions, inducing sweating makes mild cases difficult to cure and severe cases fatal (delirium, dizziness, chaotic vision), threatening life.
Taiyang disease lasting eight or nine days, resembling malaria with fever and aversion to cold, more heat than cold, no vomiting, clear and normal bowel movements, occurring two or three times a day, with a faint pulse and aversion to cold, indicates both Yin and Yang are deficient; further sweating must not be induced. Taiyang disease with fever, aversion to cold, more heat than cold, and a faint pulse indicates absence of Yang; sweating must not be induced. Dry throat contraindicates sweating. Loss of blood contraindicates sweating; inducing sweating causes chills and trembling. Patients prone to epistaxis cannot be treated with sweating; sweating causes depression of the forehead, tight pulse, staring gaze, and insomnia. Patients prone to sweating cannot be treated with sweating; inducing sweating causes mental confusion and post-urination genital pain; Yuyuliang Wan (Hematite Pill) is indicated (formula missing). Patients with chronic strangury cannot be treated with sweating; inducing sweating causes blood in stool. Patients with chronic sores, despite body pain, cannot be treated with sweating; inducing sweating causes spasms. Diarrhea contraindicates sweating; inducing sweating causes abdominal distension. Cough with normal urination or incontinence contraindicates sweating; inducing sweating causes cold reversal of the four limbs.
In Shanghan, from one to four days, if Jue (cold limbs) occurs, fever will follow; previous Jue implies subsequent fever. Deeper Jue corresponds to deeper heat; milder Jue corresponds to milder heat. If purgation is indicated but sweating is induced instead, mouth sores and redness will result. Shanghan with wiry-thin pulse, headache, and fever belongs to Shaoyang; Shaoyang contraindicates sweating. Shanghan headache, slight fever resembling wind-stroke, with spontaneous slight sweating and self-induced vomiting, if treated with purgation, increases irritability and inner distress; if treated with sweating, causes spasms, stiff body, and difficulty bending/straightening; if fumigated, causes jaundice, urinary retention, and eventually coughing with sputum. Concurrent Taiyang and Shaoyang disease with stiff neck/headache, dizziness, occasional chest binding sensation, and epigastric hardness contraindicates sweating. Taiyang disease treated with sweating leading to spasms. Shaoyin disease with cough, diarrhea, and delirium results from fire therapy coercion; urination will be difficult due to forced Shaoyin sweating. Shaoyin disease with Jue and no sweat, if forcibly sweated, disturbs Blood, which may exit via mouth, nose, or eyes; this is called Lower Jue and Upper Exhaustion, the most difficult to treat.
*Yong Lei Qian Fang* states there are four difficulties in inducing sweating for Shanghan. First, external signs: Fever and headache with sweating rather than anhidrosis, aversion to wind rather than cold, yet treated with sweating, leading to unceasing sweat (Lou Feng) or spasms. Second, pulse differentiation: Fever and headache with slow chi pulse indicate deficient Ying and scant Blood, contraindicating sweating; fever and headache with wiry-thin pulse belong to Shaoyang, contraindicating sweating (inducing sweating causes delirium). Third, internal signs: Moving qi on the left contraindicates sweating (causes dizziness, muscle twitching); on the right (epistaxis, thirst, irritability, vomiting water); above (Qi rushing to heart); below (no sweat, irritability, bone pain). Fourth, seasonal timing: Spring allows mild sweating as Yang is weak; winter forbids heavy sweating as Yang is hidden (inducing sweating causes vomiting, diarrhea, mouth ulcers, sores).
Yun Qizi states: Taiyang patterns require headache and stiff neck, fever and aversion to cold, and floating pulse before sweating can be induced.
*Liu Ren Shu* states: Faint pulse or slow chi pulse contraindicates sweating. Patients requiring sweating but experiencing epistaxis or bleeding contraindicate sweating. Complicated diseases (Huai Bing) contraindicate sweating. Women with menstruation onset contraindicate sweating. Wind-Warmth contraindicates sweating. Damp-Warmth contraindicates sweating. Deficiency irritability contraindicates sweating. Patients with abdominal pulsations anywhere contraindicate sweating. Taiyang with dry throat, severe epistaxis, or difficult urination contraindicates sweating. Already-sweated patients should not be re-sweated. Without these contraindications, even if previously sweated, if pathogens remain, re-sweating is appropriate. Failure to sweat when indicated leads to Jaundice caused by Wind-Cold injuring Yang, causing Yang to sink internally and Cold-Damp to ascend in meridians; sweating should have cleared the pathogen. Spleen governs muscles and limbs; Cold-Damp combining with internal Heat causes Jaundice. Sweating when inappropriate leads to Blood stasis and Dry Fire. Moistening fluids is superior; sweating destroys them, allowing toxicity to disturb extreme Yang and invade Yin, causing dry Blood to accumulate in the chest. Excessive sweating opens pores, causing unceasing leakage, leading to stiff limbs and difficulty moving.